Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76859	Linsitinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	MNAT1; MDM4; ATF4; ZNF394; ASH2L; MTA2; MAZ; RBBP5; THRAP3; MBD2; PEX2; STAT2; PRKDC; ZNF688; BTG1; TAF9B; ZNF32; MAX; PNRC1; PATZ1; BNC2; TSC22D3; GLI3; ZNF140; SALL2; AHR; BRD2; ZBED4; RBBP4; POLR3F; SIX1; EMX2; PCGF2; ZNF304; CNBP; HMGB1; YAP1; HOXA5; AEBP1; BRF2; MAFB; ZNF224; CUX1; ZNF551; CDK9; GATAD2A; MED6; USP22; SCAND1; NRIP1; KLF6; RLF; ZHX2; SLC2A4RG; HDAC4; LITAF; PBX3; GTF3A; FOSB; REPIN1; CTNNB1; ZFPM2; RBM39; CBX6; NR1H2; PEG3; RFX5; ZMYM2; STAT6; HOXC6; ZNF652; CITED1; ZNF91; ZNF131; PBX2; MED1; BIRC2; NFATC3; TCFL5; PSIP1; KAT6B; ESR1; CITED2; THAP11; CRK; FOS
Down-regulation	72	SMARCA4; BASP1; TAF1D; PITX1; RB1; POLR2A; TRIP6; PMS1; CREM; SAP130; SAFB2; KLF4; RUNX3; ZFP36L2; TOB1; PURA; MEIS1; ENO1; UBP1; PAWR; NR4A1; HHEX; SMARCA1; PKNOX1; NPAS2; XBP1; PAX6; FOXF2; CDX1; HOXD1; KAT2B; ZNF248; RBPMS; DNAJC2; HMGA2; ID4; YBX2; TAL1; NFKB2; ZNF43; CREB3L2; PLAGL1; HTATIP2; SIX2; EGR3; TXNIP; KDM5B; CD3D; TLE2; DAXX; MNDA; EN1; IKBKAP; TCF7; HOXB7; TSC22D1; ZBTB20; SOX9; TLE1; RBL2; KLF9; TBX3; MYCN; ZNF331; DMTF1; IRF4; NR2F1; ZNF423; TBX2; SATB1; TLE4; ERBB4