Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76858	Linsitinib	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	149	TAF10; ASH2L; PHF8; PCBD1; NCOR2; MNAT1; FOXO4; HDAC6; AATF; TSC22D3; INSR; GLI3; PMF1; MAGED1; ETV1; CTR9; MLXIPL; PIAS2; BMI1; TP53; TAF4; BRD8; NUP62; PEX2; DNMT1; NFE2L1; MEF2A; SMAD1; NONO; SALL2; EGR1; AEBP1; USP22; NFIX; HMGB3; ZNF143; ATF5; HOXC6; HOXC4; AIP; HOXA5; FOXO1; KMT2A; SIX1; BRD4; HDAC1; KAT6A; CITED1; ACTL6A; PCGF2; YEATS4; THRAP3; SMARCE1; MAFB; HOXB7; TCF21; BRF2; RARA; RBPMS; ZNF267; RUNX1; ZMIZ1; PRKDC; MEOX1; SMAD3; KLF7; SUB1; SUV39H1; VEZF1; KDM2A; MYCBP; BAZ2A; ZNF274; KMT2B; ZBTB1; RFX5; NR1I2; MLX; HIVEP2; NEDD8; FOSB; TSG101; BCL10; CEBPG; ASCL1; SOX13; HOXB6; TBP; MED1; BRCA1; TRAK1; STAT6; TCF12; MSX1; SCAND1; MLXIP; WT1; VDR; ZNF410; CBX5; MNT; BBX; HSF2; BNC2; CREB5; CBX3; ATF1; HOXA1; ERG; ING3; ZBTB18; RNF14; EMX2; MED24; HDAC9; TBPL1; TFAM; JUND; NFIB; NR2F2; MXI1; BAZ1A; RBM39; ZNF432; KDM5D; RBBP7; FOSL1; TWIST1; SOX15; HMGN3; HEY1; ESR1; TCFL5; ZNF302; NFIL3; NKX3-1; SUZ12; FOXO3; JUP; ERBB2; HTATIP2; CRK; ZHX2; PSIP1; THAP11; FOS; ARID4B; TLE1; IKBKAP
Down-regulation	103	ZNF512B; NFKB2; REL; ZNF571; ELF5; MNDA; FOXF2; SCAI; EYA2; SALL1; SNAPC4; ZNF695; URI1; DLX5; TAF1D; TFAP2A; SOHLH2; ZNF124; TBX21; FOXC1; MED17; RREB1; NFE2L2; CALR; KLF1; OVOL2; ZNF74; ZNF239; ECD; KAT2B; GRHL2; EPAS1; HHEX; NR4A3; TGFB1; ZNF711; ZNF264; CBX4; THAP7; NFE2L3; CREM; ZNF117; CENPB; NFAT5; PRDM2; ZZZ3; NFKB1; ZNF43; PHIP; TRPS1; ZNF573; CCNH; ZNF331; BHLHE41; SUPT3H; DAXX; SMAD4; EN1; ZNF141; SMARCA1; GTF2I; NR4A2; NKX2-1; MYT1L; NKX2-2; CREB3L2; DNAJC2; NEUROD1; RBPJ; BCLAF1; MYBL1; LIN28A; FOXF1; NANOG; HIRA; ARNTL2; NR1H3; BASP1; CHD1; ID1; RARG; OSR2; SOX9; FLNA; FOXE1; SATB2; TRIM32; TFAP2C; HLF; TLE2; XBP1; ERBB4; HOXD1; HIC2; EDF1; SPDEF; ABL1; PAX6; ELF3; MEIS1; RORA; MECOM; ID4