Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76857	Linsitinib	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	VGLL4; BTG1; GLI3; PHF8; TSC22D3; ASH2L; TTF2; PCBD1; TAF10; SALL2; HOXA4; MNAT1; KAT8; FOXG1; SMARCB1; LYL1; SMAD1; SPIB; ATF5; PEX2; NFIX; NFATC4; BAZ2B; TAF1D; AEBP1; ZNF688; HDAC6; TAF4; RERE; MMS19; BAZ2A; HOXC4; TOB1; FOXO1; FOXO4; MTF2; NFE2L1; TWIST1; PRKDC; ZKSCAN1; MEF2A; HOXA5; HDAC1; CREB3; MED4; ETV1; TRIM22; NAB1; DNMT1; BRF2; FOXD1; UBE2I; RARA; PFDN5; PNRC1; SAP30; ACTL6A; ZNF91; BTAF1; PMF1; BNC2; ZBTB18; CREBZF; MEOX1; BRD4; KLF7; MITF; MAX; SCAND1; NRIP1; GTF3A; RBPMS; ZNF281; DDIT3; BATF; MAZ; AIP; HOXC6; INSR; HMGB1; CITED1; VEZF1; HDAC9; HEY1; STAT6; BRD8; TOX; ZFPM2; CUX1; YAP1; CITED2; HDAC5; MED13; MAGED1; HOXB6; PCGF2; UBE2B; LITAF; ZMYND8; STAT1; PTTG1; PAXBP1; NCOA3; RLF; NCOR2; EMX2; BAZ1A; RBBP7; BBX; MED1; IRF9; HOXB7; KLF6; CREB5; SIX1; ZNF432; EGR3; CREG1; ZMYM2; HOXB2; FOXO3; TCFL5; CTBP2; PSIP1; ATF3; FOSB; PBX2; ARID4B; CRK; FOS; THAP11
Down-regulation	104	ZNF512B; CCNA2; NFKB2; NFE2L2; TLE2; REL; BCLAF1; RREB1; DEAF1; TULP4; JUN; NKX2-1; NKX2-2; ZNF571; WWC1; BCL11B; ZBTB38; SREBF2; PURA; ZNF264; TAF1A; CCNE1; FOXF2; LIN28A; CEBPZ; TDP2; URI1; ZNF74; ETS2; ZSCAN31; TCF20; DNAJC2; ZNF180; XBP1; SMARCA4; HLTF; TXNIP; TBL1XR1; FOXC1; BCL3; ZNF586; DLX5; ZNF711; KAT2B; CREM; BACH1; SP3; ZNF22; SOHLH2; ZNF331; ETV5; PEG3; ZNF124; NANOG; MNDA; BHLHE41; RUNX3; SUB1; ID1; NR1D2; ELF3; FOXL2; CENPB; NFE2L3; TGFB1; SMAD6; AES; ABL1; PPP1R13L; FLNA; GTF2I; PITX1; NFAT5; ZNF551; TAL1; HMGA2; TEAD4; MYT1L; KLF10; ZNF652; ENO1; HES1; TRPS1; EN1; KLF11; PHIP; SOX9; OSR2; HIRA; TGIF1; FOXF1; PLAGL1; TBX3; DACH1; PHF20; NR4A2; NR2F1; DAXX; GATA3; ERBB4; HOXA10; SATB1; ID4; KAT6B