Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76831	Gsk-2126458	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	169	ASH2L; TSC22D3; TAF10; MNAT1; PCBD1; NFE2L1; PEX2; HDAC6; PRKDC; BRD8; FOXO4; PHF8; ZNF688; ZEB2; NCOR2; NFIX; YEATS4; HTATIP2; BRF2; HOXA4; CREB3; MAZ; HCFC2; HOXA5; PMF1; AIP; MEF2A; TFEC; KAT5; FHL5; FOSB; SPEN; NRIP1; ETV1; PSMD9; THAP1; HEY1; NRBF2; AATF; SMAD1; NR3C1; HDAC9; MXI1; BRD4; USP22; SAP30; TSG101; ARNTL; DRAP1; ZNF394; NFIL3; FOXO1; TMF1; PTTG1; KLF6; NCOA6; C1D; AHR; HDAC5; HOXC6; NFKBIB; KAT8; GLI3; STAT6; NFKBIA; ELF1; KLF7; GTF2A1; CIR1; ERBB2; HOXC4; KDM2A; SOX4; RBBP8; NR2E1; SMAD2; MED1; EP400; PDLIM1; BMI1; SUV39H1; TRAK1; MLXIPL; ATF5; PPARGC1A; TEAD1; NR2C1; CUX1; TBX19; ZNF226; PSMC3IP; NCOA4; CTR9; MSX1; ASXL1; KAT7; FOXD1; AEBP1; MAFB; RBPMS; HIVEP2; NFIB; RUVBL2; SCAND1; RNF14; TP53; SP2; TOX; SMARCA2; USF2; EED; ZBTB43; ELF4; RFX7; FOXO3; CEBPG; MED13; RLF; VEZF1; SMAD3; HSF2; ING3; TRIP4; ZNF410; NEDD8; BRCA1; HBP1; NR1I2; VDR; RBM39; ZNF432; ATF4; HDAC1; COPS5; FOXN3; SIX1; HOXB7; RBBP7; KLF9; ZBTB16; BNC2; CBX3; SERTAD2; TBP; NR1H2; LPIN2; EMX2; ATF1; ID3; NCOA3; HMGB3; MNT; BAZ1A; ASCL1; ZNF83; FOS; TWIST1; KDM5D; IRX5; PSIP1; RUNX1; ARID4B; JUND; RHOA; ERG; COPS2; CITED2; CRK; IKBKAP
Down-regulation	138	ZNF512B; JUN; TOX3; MNDA; PIAS4; BCL11A; NFE2L2; NFKB2; ZNF692; SMARCA1; NKX2-1; CAMTA1; FOXF2; ECD; NFE2L3; LIN28A; MYC; TLE2; ELK3; ZNF682; RREB1; ZNF711; CALR; REL; TAF1A; ZNF571; PRDM1; GRHL2; E2F6; SOHLH2; ZNF43; HHEX; SNAPC4; MYCL; ZNF239; ZNF264; ETS2; TRIM16; ZNF573; BCLAF1; ZNF611; PMS1; FOXF1; SSX1; ZNF589; CEBPZ; TCF25; BCL3; AES; SP3; OSR2; TFAP2A; NEUROD1; ZSCAN31; TCF20; IRF6; HES1; ARID5B; CBX4; ZNF117; HIRA; SOX11; ZFP36L1; NKX2-2; NFAT5; ZXDC; ZNF248; ZNF273; ZNF331; DNAJC2; HMGA2; SSBP2; ABT1; TGFB1; ZNF124; URI1; ZNF652; SALL1; ZNF141; DAXX; RBFOX2; ERBB4; MEIS2; MGA; GTF2I; CREM; TERF1; ELF3; PHIP; BASP1; ZFPM2; TBX3; MEOX2; TCF4; SOX9; ETV5; NFE2; NR4A3; ZIC3; CTNNB1; ARNTL2; FOXE1; ZFP36L2; POU2AF1; JUNB; MYCBP; HIC2; TCF7; ETV4; NANOG; ID4; TFAP2C; RARG; PAX6; BHLHE41; DLX5; TBX2; TGIF1; TP63; CD3D; DACH1; MECOM; TRIM32; FOSL1; KLF10; TRPS1; NR4A1; CRYM; CBX7; MYBL1; EGR2; LEF1; ID1; NR4A2; ISL1; NKX3-1; ZNF423; SATB1