Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76829	Gsk-2126458	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	141	SMARCD2; TSC22D3; BTG1; ASH2L; PRKDC; TAF10; ACTL6A; HOXA4; HDAC6; DDIT3; ZNF688; PHF8; NFIX; PCBD1; MAZ; MNAT1; TTF2; TRAF6; SP100; UBE2I; TAF7; ELF1; HCFC2; KLF6; MMS19; MXI1; BMI1; PMF1; NRIP1; FOSB; ELF4; NFKBIA; ZNF205; EZH1; RELB; SMAD5; FOXO4; NR3C1; TP53; MLLT10; ELK1; NFE2L1; ZKSCAN1; KDM5D; MAFB; DNMT1; ZNF669; YEATS4; ADNP2; PEX2; HBP1; NFIL3; TSC22D4; BRCA1; ZNF224; TP63; ASCL1; SMAD4; NFYC; ZNF768; GTF3A; BRF2; PNRC1; AHR; HOXA5; HSF2; PBXIP1; ZNF721; USP22; PIR; TRIM29; CNBP; BAZ2B; RFX7; PIAS2; BAZ2A; MAF; KAT6A; ZNF32; RNF10; RBBP7; BRD4; GFI1; BRD8; CNOT2; TCFL5; NFATC3; NCOR2; FOXO3; SIX1; VEZF1; PCGF2; ZNF160; KAT2A; ATF4; TCF21; MITF; RLF; RBPMS; USF2; TSG101; TFAM; STAT6; HEY1; TAF11; ZNF432; ZNF532; ZMYND8; KLF5; LITAF; ZNF83; TSC22D2; KLF7; NCOA3; TWIST1; EZH2; FOXO1; HMGA1; TSC22D1; SCAND1; MLXIP; MED24; ARID4B; AEBP1; SAP18; IRF9; ZSCAN18; ATF3; TBPL1; SNAI2; TLE4; INSM1; EMX2; CRK; ATF1; HTATIP2; TLE1; CITED2; RHOA; FOS; PSIP1
Down-regulation	139	ZNF512B; MYC; TAF1A; ZNF239; RREB1; NFKB2; GCFC2; WWC1; FOXK2; SNAPC4; CDYL; REL; ZNF22; CEBPZ; ADRB2; ZNF444; ZNF264; NFE2L2; SMARCA1; ZBED2; SP3; ZFP36L1; NKX2-2; GTF2F1; RBFOX2; ZNF146; URI1; CAMTA1; FOXF2; ZNF124; PMS1; DEAF1; ZNF571; BACH1; SALL1; DNAJC2; ZNF180; SMARCA4; BCL11A; SOHLH2; GRHL2; TLE2; LIN28A; ID1; FOXC1; HIPK2; WT1; HLF; TRIM28; TRIM32; IKZF1; ZFHX3; HMGA2; HHEX; CREM; UBE2L3; SSX1; YAP1; ELK3; BCL3; ZNF711; CBFB; ZNF467; ARID5B; E2F6; ZZZ3; ABL1; MGA; HIC2; HLTF; NR5A2; SOX11; PAWR; ZNF331; HOXC10; DAXX; NFE2; TCF20; MNDA; CALR; CBX4; TOB1; AR; SOX9; ZNF43; CBX6; KAT2B; UBTF; TRPS1; NANOG; AGO2; MYT1L; BASP1; RBBP8; NOC2L; RUNX3; TGIF1; E2F3; NFAT5; NR2F1; HIRA; CERS6; RORA; LEF1; HES1; RING1; FOSL1; ZEB1; ZBTB38; ZFHX4; TFAP2C; HDGF; ZIC1; PLAGL1; STAT4; ID4; MYBL1; CREG1; PRRX1; PHF20; WWTR1; HOXD1; ZNF423; NFE2L3; PBX1; GATA6; TCF7L2; EN1; FOXF1; IRF4; LMCD1; MECOM; KLF10; NR1H2; MEIS2; TCF4; HOXA10; SATB1; KAT6B