Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76824	Gsk-1059615	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	TAF10; MAZ; HEY1; TP53; PCBD1; ELF5; PHF8; UBE2I; AFF4; KMT2A; HOXA4; RFX7; POLR2A; ASH2L; BRD4; BAZ2A; CHD4; RELA; TSC22D3; HMG20A; TSC22D4; MBD2; HOXA5; BRD2; FOXO4; NCOR2; CCNT1; ETV1; CAPN15; PIAS1; ATF5; EP400; FOXD1; KDM2A; GATAD2A; CITED1; USP22; SOX9; PRKDC; NRBF2; PDLIM1; ELF1; SPEN; PIAS3; MMS19; AATF; ADNP; MEF2A; MTF2; NFATC1; TOB1; ATF7IP; BAZ1A; KAT6A; HES1; BTAF1; HDAC6; PIAS2; NR2E1; MTDH; TFCP2L1; NUP62; SERTAD2; KMT2B; TOX3; MED24; BPTF; MAGED1; SIX1; BRF2; MED1; SIX2; AIP; SPIB; EYA2; YAF2; ZBED4; SSRP1; ZNF274; RFX5; PTTG1; ELF4; CREBZF; ARID1A; ARNTL; CHD7; SMARCA2; STAT6; CENPF; TFAM; BRD8; FOXA2; ID3; NFIB; HDAC1; ZNF83; HSF2; HDAC9; SOX15; HOXC6; NFIL3; SIM2; ASCL1; RBBP7; FOXO3; HMGB3; SATB2; SNAI2; TSC22D1; KLF7; ZNF629; VDR; MSX1; CREG1; TBP; HMGA1; KLF5; ERG; NR2F2; MYRF; ZNF12; BIRC2; KDM5D; ARID4B; ATF1; IKBKAP; MLXIP; AEBP1; HTATIP2; ZBTB16; EGR3; EMX2; CRK; PSIP1; THAP11; FOS
Down-regulation	98	LIN28A; PIAS4; TFAP2A; ZNF512B; ZFPM2; NFKB2; SMARCA1; FOXF2; FOSL2; ZSCAN31; MNDA; JUN; ZNF611; KAT2B; BACH1; SOHLH2; BASP1; TAF1A; ZNF665; NKX2-2; ZNF239; CREM; NFE2L2; GRHL2; ZNF586; ZFP36L1; NEUROD1; NANOG; ZNF652; TLE2; RBFOX2; TCEA2; AES; ZNF43; GATA6; ZNF160; ZNF423; ZIC1; PRDM1; BCL11A; RB1; IKZF1; PEX14; TGIF1; MYBL1; REL; XBP1; DAXX; RREB1; SP3; MEIS1; PAWR; ZIC3; CARHSP1; SUZ12; FLI1; HOXD3; ETS1; PEG3; MECOM; NFE2L3; FOXF1; ZBTB38; MYT1L; ESR1; TRPS1; PAX6; ARID5B; BNC2; HIRA; HHEX; OSR2; NR0B1; MEIS2; DNMT3B; PBX1; PBX3; IRF7; E2F2; CTNNB1; ZNF117; ZNF331; ERBB4; KLF4; HLF; ZBTB20; HOXB2; HOXD1; PHF20; TCF4; ZNF131; TBX3; WT1; HIC2; NFATC3; NR4A2; SATB1; CITED2