Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76822	Gsk-1059615	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	TAF10; TSC22D3; PCBD1; FOXO4; ASH2L; ZBTB7A; NFE2L1; MAZ; NCOR2; PHF8; PRKDC; HMG20B; HDAC6; EP400; KDM2A; HOXA4; BAZ1B; CHD8; PMF1; HOXA5; MMS19; CTR9; ZNF688; ETV1; MITF; TP53; CUX1; MAGED1; TRRAP; NRBF2; JARID2; RBPMS; TCERG1; ATF5; BRD8; AATF; NFKBIB; RCOR1; PIAS2; MEF2A; BTAF1; AIP; BMI1; USP22; KDM5B; NUP62; HMGB3; MBD2; ELK1; GATAD2A; HOXC6; AEBP1; TFEC; MAFB; FOSB; CREB3L1; HCFC1; TMF1; ERBB2; BRF2; TAF4; KAT6A; FOXD1; CREBZF; MTDH; ZNF84; MED1; ARNTL; NPAS2; SMAD1; NEDD8; ATF7IP; PITX1; SCAND1; TSC22D2; SIX1; SAP30; USF2; TFCP2L1; MAF; NFKBIA; SMARCA2; MED24; RFX7; HLTF; FOXO3; NCOA3; PIAS3; HOXC10; GATA4; SUV39H1; LPIN2; SETD3; MYRF; AFF1; TOB1; SIM2; DDIT3; BRD3; TBP; NR3C1; TLE4; TXNIP; TBL1X; BAZ1A; RNF141; KLF6; SOX4; BCL11B; CENPF; UBE3A; STAT6; ATF1; RUNX1; IKBKAP; HEY1; NFATC1; HOXB7; BRCA1; ZMYND8; BRD4; KDM5D; TCF21; ERG; HOXB6; MNT; MLXIP; HTATIP2; NCOA4; EDF1; NCOA2; ARID4B; MEOX1; CITED2; MKL2; EMX2; TCEB2; FOXN3; FOXO1; KLF2; RHOA; KLF4; KAT6B; JUP; FOXJ3; FOS; CRK; THAP11
Down-regulation	140	ZNF571; ZNF22; ZNF239; JUN; ZNF264; SOHLH2; REL; DLX2; ARID5A; RAD21; NFKB2; TFAP2A; HHEX; SNAI1; NEUROD1; ZNF136; ZNF586; ZFPM2; CREM; TLE2; SUPT3H; CAMTA1; NFE2L2; TAF1A; CDC5L; PMS1; SMARCA1; PAX6; ZBTB44; ZNF573; VGLL1; SOX5; ZNF124; URI1; MNDA; ZNF43; GATA6; TOX3; ZBED2; SUMO1; NFKB1; ZNF74; ZNF430; IRF6; ZNF415; NFE2L3; ZNF180; ECD; MYBL1; ZNF623; PHOX2B; ARNT2; GRHL2; MYT1; CHD7; ZZZ3; NR4A3; TDP2; E2F6; SP3; ACTL6A; BHLHE41; KAT2B; LIN28A; KDM4C; RBFOX2; ERBB4; SOX10; MED17; ZIC3; MEIS2; DAXX; TBX3; NKX2-2; ZNF33B; ZNF331; RBBP8; FOXF2; MYCL; PRRX1; ZNF665; MEIS1; CALR; ZNF652; TRPS1; NR0B1; CBX4; RING1; TGIF1; TRIM32; NKX2-1; PROX1; OSR2; PAWR; ZNF253; HIRA; DLX5; EN1; ID4; SALL1; OLIG2; WWTR1; NR1D2; NANOG; TFAP2C; NR4A2; ZNF551; BACH2; ELK3; DACH1; ETS1; MYCBP; HIC2; CHD9; ZBTB20; DEK; SOX9; ZNF423; ZNF117; CTNNB1; NFAT5; KLF11; CREB3L2; ESR1; LEF1; MECOM; ZIC1; ID1; TBX2; WT1; IRF7; NR2F1; RORA; ABL1; TCF4; NFATC3; TLE1; FOXF1; SATB1; ATF3