Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76815	Doramapimod	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	ASH2L; PHF8; TAF10; JARID2; ETV1; PRKDC; PCBD1; VGLL4; MED1; PEX2; PCGF2; RBM14; TP53; NUP62; VEZF1; ZNF672; TCERG1; NRBF2; MNAT1; SMARCA2; MLX; NCOR2; PIAS2; HDAC6; TAF4; ELK1; CTR9; RELA; AATF; PMF1; BMI1; SMAD5; USP22; MAZ; KAT6A; MTDH; DDX5; NRIP1; ZNF473; TSC22D4; KAT7; TBP; MSX1; ADNP; HSF2; CRY1; CBFB; ZNF516; ZNF267; BAZ2B; NR2E1; ERBB2; GABPB1; RFX7; KDM2A; PHF2; MED24; POLR3F; GATAD2A; RXRA; ZBTB11; BATF3; CHD7; FOSL1; HLTF; BAZ1B; HEY1; SMAD1; YAF2; TSC22D2; FOXO1; AFF1; EED; BAZ1A; MITF; UBE3A; ZNF410; SUV39H1; CITED1; BLM; STAT1; BRF2; ZNF281; RBBP7; MAGED1; FOSB; NKX3-1; ZMYM2; ZNF32; SMAD7; HMGB3; CCDC59; PTTG1; MYCBP; AEBP1; ATF1; NCOA4; ASCL1; PIR; ZBTB18; HOXC6; RNF14; HTATIP2; HDAC1; SIX1; SF1; SUB1; MTF2; EGR3; ZBTB1; MAFB; SAP18; KDM5D; ZNF532; SPEN; MXI1; IKBKAP; PSIP1; ZNF432; EMX2; RUNX1; FOS; MTA1; EGR2; EZH2; FOXO3; CRK; HOXA10; PDLIM1; RFX5; TLE1; ARID4B; THAP11; LEF1
Down-regulation	101	NFE2L2; NFKB2; ZNF264; FOXF2; SOHLH2; TCF7L1; TLE2; REL; BCL11A; ZFPM2; ZNF623; NEUROD1; ZNF43; VGLL1; RBFOX2; PRDM2; TBX21; DLX5; MNDA; HHEX; TFAP2A; NKX2-2; MYCL; ZNF711; MYBL1; ZNF611; ZNF74; ZNF573; DLX4; NKX2-1; TULP3; ST18; ZNF124; IRF6; AHR; PEG3; CREM; RB1; E4F1; LIN28A; GRHL2; ZNF512B; E2F8; NFE2L3; ZIC1; HOXD1; ZNF423; KAT2B; DAXX; ZSCAN31; MEOX2; ZNF117; PAX6; TRPS1; OSR2; HIRA; ZNF273; PCGF3; EN1; RARG; FOSL2; CREB3L2; ZNF331; HOXD3; CEBPD; SMAD6; NANOG; FOXF1; MEIS1; NR5A2; NR4A1; BASP1; PHIP; NR4A3; TCF4; SMARCD3; IRF7; GATA6; BHLHE41; NAB2; HIC2; NR4A2; ID4; KLF5; NFAT5; SMARCA1; ERBB4; TCF7L2; HLF; TBX3; ID1; ELF3; NR2F1; PHF20; HOXB2; PLAGL1; WT1; DACH1; MECOM; SATB1; ID2