Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76813	Doramapimod	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	PHF8; TAF10; ASH2L; ZBTB18; PCBD1; MAFG; TAF1D; SMAD1; PRKDC; SRF; EGR1; ZNF143; ZNF274; MAZ; NRBF2; GLI3; PMF1; LYL1; ETV1; TCERG1; CTR9; ZBED2; ZNF672; ATF5; MTA1; MLXIPL; TRRAP; FOSL1; BRD2; NFIX; NR2E1; ZNF281; GMEB2; HDAC6; ELK1; FOSB; NFATC4; USP22; KLF7; MAX; HDAC9; BRD4; AIP; NUP62; SPEN; CEBPG; PCGF1; BCL10; BAZ1A; GATAD2A; SMAD5; TP53; CUX1; MLX; ELF4; TOB1; NCOR2; NFE2L1; BRF2; RNF6; GATA4; NEDD8; HDAC1; RUVBL2; CITED1; EGR3; LOXL2; MYB; NR1I2; STAT1; VDR; HSF2; RFX7; RUNX1; BRPF1; TRAK1; SPIB; ERG; KAT6A; TAF9; YAP1; MAFF; EMX2; EED; SUV39H1; TSC22D2; FOXO1; MED1; TBP; MLXIP; SCAND1; FOXD1; ZNF226; ZNF410; HMGB3; ZMYM2; MAFB; FHL2; AEBP1; NCOA3; MNT; TCFL5; GTF3A; SOX15; RBPMS; BIRC2; SAP18; MAGED1; JUND; HOXC6; NRIP1; SIX1; TOX; MTF2; ATF1; CRK; SNAI2; ATF3; FOS; SOX9; ARID4B; IKBKAP; THAP11
Down-regulation	117	NFE2L2; ZNF611; TLE2; ZSCAN31; ZNF264; REL; NFKB2; TXNIP; BTG1; FOXF2; AHR; CAMTA1; ZNF512B; JUN; KAT2B; ZNF124; ZBTB38; ZFHX3; GRHL2; CREM; PSMC3; MNDA; ZNF571; ZNF160; TCF25; NKX2-2; URI1; ECD; HIVEP1; TFAP2A; ZNF136; ZNF586; ZNF112; NKX2-1; LIN28A; ZNF711; ID1; ZNF239; NFKB1; ELF5; ZNF33B; SOHLH2; ZNF141; ZNF331; TRPS1; ZFPM2; JAK2; HSBP1; ZNF43; ZNF573; ZNF665; TERF1; PAX6; ZNF117; PHIP; DLX5; ESRRG; BCLAF1; TGIF1; STAT4; FOXC1; PRDM1; WWC1; ZNF253; MYBL1; ZNF721; RUNX3; ZNF248; AES; TFDP2; FOXF1; MEOX2; CRYM; TCF4; ERBB4; DDX17; NEUROD1; MEIS1; KLF4; HBP1; XBP1; OSR2; ZNF652; E2F2; ZNF551; ZXDC; ZBTB20; HOXB2; TCF7; TFAP2C; POU2AF1; UBE2B; HOXA5; ARID5B; TGFB1; NFAT5; KLF9; PEG3; ENO1; MEIS2; ID4; NR1D2; IRF4; ZNF423; BHLHE41; CREB3L2; ELF3; DACH1; TBX2; PHF20; MECOM; CREB1; ID2; SATB1; NR4A2; TBX3; DAXX