Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76806	Celastrol	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	RXRA; STAT1; KMT2A; PEG3; ZBTB18; ATF4; MAFB; ZNF281; TBL1X; ZNF202; SF1; TFCP2L1; TEAD3; MTDH; AFF1; MTA1; SPEN; NFIB; PAWR; RBL1; TRIM22; RARA; MAGED1; CNOT1; HNRNPD; MEF2A; AHR; FOXJ3; NRIP1; BRD2; TOB1; CHD4; BCL3; NKX3-1; ARNTL2; CTCF; WWTR1; NCOA6; WWC1; PPARGC1A; GATAD2A; HMGB1; ZNF512B; ZNF423; ZFPM2; KDM2A; ZFHX4; KLF3; CBFB; NR2F2; FOSB; TEAD4; ZSCAN31; SOX4; EDF1; SCAND1; BRD4; ZMYND11; NCOR2; YWHAB; ZMIZ1; SIX1; CBX5; EGR3; FOS; ZFP36L1; ANKRD1; RBM39; KLF10; SERTAD2; CBX6; KLF6; YAP1; HMGN3; CEBPA; RBBP5; SMAD1; AEBP1; KDM5B; CREB1; MNDA; HDGF; PIR; BNC2; ING2; OSR2; MLXIP; DNMT3B; BHLHE41; BIRC2; HLF; POU2AF1; PBX3; FOXO1; MXI1; NFATC3; HOXC6; EGR2; JUND; CITED2; THAP11; ESR1; HMGA2; KAT6B; NR1H2; DAXX; ZNF331; NR4A2; MEIS2; PSIP1; ZIC1; TLE1; CRK
Down-regulation	79	VPS72; KAT8; TULP4; TCERG1; PNRC1; ZNF587; ZBED2; ZNF85; ZNF529; BCL11A; PSMC3; TXNIP; GTF2F1; SMARCA4; CDX2; ETS2; INSM1; ZNF136; ADRB2; PTTG1; CDX1; ZNF267; TAF1D; MKL2; ZNF43; MYCBP; HAND1; HTATIP2; NKX2-1; MLX; HSBP1; ST18; HDAC9; BATF; FOXG1; KAT2A; ZNF91; ZNF273; DEK; PBX1; ZNF83; CREBZF; ZNF117; TOX; CREM; CCNC; BRWD1; ZBTB16; ARID4B; POLR3C; MSX1; MAFF; KLF11; RRN3; HOXA1; HEY1; TSC22D3; SAP30; MYBL1; ARID5B; HES1; IRF6; TLE4; NCOA2; ZNF12; ZNF302; SMAD3; HIC2; PLAGL1; ZEB1; HOXA10; TBX3; TBX2; DACH1; ABL1; DMTF1; TCFL5; SATB1; ID2