Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76805	Celastrol	GSE92742	MCF10A	Human	6h	10uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	129	GABPB1; DDIT3; STAT1; VGLL4; PCBD1; ASH2L; MXD1; AFF4; NRBF2; PHF8; RYBP; PMF1; ZNF394; SMAD5; ZNF672; NRIP1; BRD2; ZNF143; CEBPG; NFE2L1; SIX2; KDM5A; HEY1; BTAF1; BRD4; RLF; TMF1; ZNF165; AATF; RBM14; BRPF1; TAF10; ZNF473; NCOA3; JARID2; VEZF1; SPEN; IKZF5; KMT2B; ZBTB43; DNAJC1; RXRA; LMCD1; UBE2I; BRF2; IL16; ZNF266; JUND; XBP1; BBX; BAZ1B; TOB1; TSC22D2; KAT6A; ATF7IP; CRY1; RBPMS; HDAC6; GATAD2A; FOSL1; BRD8; KDM2A; MED1; GLI3; CCNE1; MLX; USP22; ID3; CENPF; ELF5; ANKRD1; TSC22D3; CTR9; SMAD1; YAP1; INSR; ATF4; POLR3F; ZNF384; CITED1; FOXD1; HDAC5; CHD1; MSX1; LITAF; ZFX; SCAND1; PIR; ZNF410; ZBTB18; TBP; BANP; IRF9; ZNF140; SERTAD2; HTATIP2; VDR; ARID4B; RBM39; EZH2; ATF3; KLF7; CDK9; CREB5; PITX1; SOX9; HSF2; NR2F2; HOXB7; NCOA4; PTTG1; SUB1; HOXC6; AFF1; FOXO1; SIX1; TBPL1; PSIP1; NKX3-1; INSM1; BIRC2; FOS; KDM5D; NFIB; ASCL1; IKBKAP; CRK; ABL1; DACH1
Down-regulation	98	ZNF512B; MYC; ZNF623; SOHLH2; ZNF264; SCAI; ZBED2; NFE2L3; TLE2; REL; CDK2; RBFOX2; DEAF1; ADRB2; PLAG1; ZFPM2; YBX3; LIN28A; NFKB2; CTBP1; ZNF589; MECP2; SMARCD3; ZNF329; TFAP2A; TBL1XR1; KAT2B; NFKBIA; NEUROD1; TRIM22; TAF12; BCL11A; URI1; ZNF667; MYT1L; NANOG; HMGB2; ZNF43; NR1H3; ZNF415; OSR2; MED14; BACH1; ZBTB20; MYBL1; TERF1; ZNF304; PRDM2; ELK3; ZSCAN18; GTF3A; BCL3; PKNOX1; HDAC4; ZNF331; SALL1; HOXD3; SLC2A4RG; CTNNB1; NKX2-1; ZIC1; FOXF2; FLNA; CBX3; SMARCA1; STAT3; PCGF3; MEIS1; AES; CREM; HMGA2; MAF; TGFB1; TXNIP; CUX2; ARID5B; NR4A2; TGIF1; PBX3; HLF; TCEA2; FOXF1; ZBTB16; SOX17; ZNF423; TRPS1; CBX7; ELF3; NR2F1; SATB1; WT1; TCF4; KLF10; TCFL5; ID4; MECOM; DAXX; KAT6B