Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76802	Chir-99021	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	PPRC1; PHF8; ASH2L; BRD2; THAP1; NFE2L1; TRAF6; TAF10; GATAD2A; ZNF473; TAF4; HDAC6; MAZ; MED1; SRF; MTA2; BMI1; MDM4; MMS19; NFIX; CRY1; HCFC2; ZNF593; ZNF274; HEY1; TCERG1; TAF1D; DNMT1; NR2E1; PIAS2; ADNP; NFYB; CAPN15; ZBTB7A; BAZ1B; ZNF337; ELF4; NUP62; FOXN2; PRKDC; TRIP6; ZBTB24; ETV1; BATF3; ZNF222; RBM14; AEBP1; RFX7; TFAM; FOXD1; CCNT1; ZNF576; CTR9; ADNP2; ATF5; BRD4; ZNF668; TSC22D4; MTDH; SAP18; USP22; BAZ2A; FOSL1; SPEN; SUV39H1; PCGF1; BAZ1A; LZTS1; PMF1; SMARCA2; RBPMS; RUNX1; ZNF23; NR1I2; BRF2; TFCP2L1; ZNF574; MAFF; ETS2; SMAD5; HDAC9; PTTG1; NCOR2; ZBED4; HMBOX1; HMGB1; CEBPG; HSF2; GATA4; TBP; HDAC1; ZNF140; KLF6; MYCBP; CITED1; ZNF432; CNBP; LPIN2; ZNF281; ZBTB18; FOSB; TAF9; YWHAB; ZNF266; SUB1; ASCL1; FOXO1; ATF3; RRN3; SIX1; RNF6; SOX15; HTATIP2; IKBKAP; KLF13; NRIP1; SNAI2; KDM5D; ZNF131; KLF7; EGR3; ATF1; ZBTB16; MSX1; MYRF; ARID4B; FOXO3; PSIP1; PIR; ZFP36L2; PDLIM1; EMX2; ERG; CRK; TWIST1; TLE4; HOXC6; FOS
Down-regulation	96	ZNF611; NFKB2; SMARCA1; MNDA; PEG3; BACH1; VPS72; ZSCAN31; GRHL2; SOX11; NFE2L2; SMARCD3; ZBTB20; MEIS2; LIN28A; PCGF3; ZNF665; TFAP2A; REL; ZNF160; ZFP36L1; TCF25; ZNF586; BCL11A; ZNF331; TOX3; HBP1; TLE2; OSR2; ECD; CREM; CALCOCO1; FOXF2; GATA6; RBFOX2; TRPS1; ZNF512B; ZNF721; MYBL1; CARHSP1; NR0B1; NEUROD1; KAT2B; NKX2-2; SP3; TCF4; E2F8; NR4A2; ARID5B; ERBB4; PFDN5; SALL1; NKX2-1; HOXB6; PHIP; MEOX2; FOXC1; NR5A2; DLX5; NFE2L3; HOXB5; BACH2; TGIF1; TBL1X; INSR; TFAP2C; POU2AF1; TBX3; ZNF117; CTNNB1; FOXF1; KLF11; ZNF652; CRYM; DACH1; ESR1; ETS1; HIRA; TXNIP; HOXB2; ID4; SPDEF; NFATC3; IRF6; BHLHE41; MECOM; PAX6; HMGA2; RORA; ELF3; PHF20; ZNF423; ID2; SATB1; ID1; TLE1