Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76782	Afatinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	PEX2; PHF8; ASH2L; CREB3; TSC22D3; PCBD1; PSMC3; FOXO4; TAF10; ZNF184; VEZF1; PIAS2; HDAC6; THAP1; PTTG1; PMF1; MED7; C1D; TMF1; ZNF394; KAT6A; SOX11; MNAT1; ZNF222; SREBF1; TRIM22; HOXA5; SALL2; DDIT3; SMAD1; NFE2L1; PRKDC; MAGED1; HEY1; AEBP1; UBE3A; MITF; TRIM33; ZNF430; ARNT; CTR9; DDX5; BRF2; MYNN; NCOR2; RUNX1; LITAF; ZNF267; ZNF432; TBP; BTAF1; UIMC1; ING3; MLX; IKZF5; BAZ2B; ZBTB18; ZNF189; POLR3F; HOXB7; MTA1; NCOA4; NRIP1; ZBTB43; ARNTL; SCAND1; SMARCA2; ZNF32; RBBP5; BBX; ZNF468; EMX2; MED1; CRY1; HSF2; SUV39H1; ZNF24; SP2; BRD8; MED6; ZNF140; TRIM29; FOXO1; BNC2; CITED1; TRIP4; CNOT2; EGR2; STAT6; HDAC9; MSX1; ATF2; HOXC6; HIPK1; MED23; TSC22D2; HLX; ZNF131; ZEB1; ZNF274; NR1H2; MYCBP; ZNF83; MED24; SAP30; ATF1; KLF6; RLF; SMAD3; SAP18; JUND; SIX1; TBPL1; KLF7; HTATIP2; AFF1; RBPMS; TWIST1; FOSB; MEIS2; BAZ1A; PIR; PSIP1; NFIB; KLF2; RBBP7; EZH2; SHOX2; TOX; KAT6B; IKBKAP; ID3; ZHX2; ARID4B; CRK; LEF1; HOXA10; SATB1; ATF3
Down-regulation	85	MYC; ZNF239; TULP4; ZNF512B; PA2G4; NKX2-1; PRDM1; NFKB2; SNAI1; URI1; FOXF2; SNAPC4; HSBP1; PAWR; THAP4; EPAS1; LIN28A; TAF1A; NFE2L2; RB1; HHEX; SMARCA1; RREB1; NFAT5; SSBP2; MYBL1; ZNF124; MYCL; HMGA2; SMAD7; ZFP36L1; SOHLH2; GRHL2; MED17; BCL11A; NKRF; ETV4; ZBED2; NEUROD1; AHR; FOSL1; EGR4; XBP1; TXNIP; TRPS1; NFE2L3; ARID5B; DAXX; BHLHE41; NKX2-2; CBFB; CREM; SALL1; CREB3L2; KAT2B; PHIP; MNDA; FOXL2; GTF2I; EN1; ERBB4; TBX3; POU2AF1; HIC2; KLF11; HMGN3; FOXC1; HDGF; TLE2; RBL2; NFATC3; HLF; NAB2; ZBTB16; ZNF117; FOXF1; HIRA; IRF6; SPDEF; KLF10; ID1; ID4; FOS; PHF20; ID2