Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76781	Afatinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	MDM4; TAF9B; ASH2L; RARA; TSC22D3; PHF8; ZNF184; TP53; PEX2; TSHZ2; ZNF672; PRKDC; MEF2A; RUNX3; AEBP1; PPARGC1A; PCGF2; MAFB; HAND1; CTR9; NFIX; MAGED1; ZEB2; MMS19; BNC2; NFE2L1; ZNF211; NR2C1; RCOR3; GLI3; USP22; RLF; CUX2; SMAD7; ZNF281; MED24; EMX2; NFYC; SALL2; ZNF432; ZBTB18; NCOR2; LPIN2; ZFHX4; RBBP8; ZNF45; MED6; SCAND1; TRIM33; HOXC6; BRF2; MED1; NFIB; HSF2; ID1; PIR; SMAD1; HEY2; ZFP36L1; UBE3A; KDM5D; HMGN3; HMGB3; ELK3; MYRF; FOXO1; FOXN3; ZBTB1; SUB1; ZMIZ1; HLX; CENPF; KLF2; CREG1; ERG; NFIL3; ELF3; ATF1; COPS2; NCOA2; PSIP1; SHOX2; EYA1; ARID4B; MEIS2; MECOM; CRK; TLE1; THAP11
Down-regulation	90	MYC; NKX2-2; SATB2; BCL11A; HIF1A; REL; ZNF239; FOXF2; URI1; HOXB6; DLX2; TLE2; PURA; NEUROD1; TOX3; LOXL2; ZNF124; MED17; CDX1; CREM; CDYL; E2F5; IRF3; BHLHE41; ZNF165; FOXA1; ZBTB38; ZBED2; TGFB1; EGR4; PEG3; WWTR1; TXNIP; KAT2B; SSBP2; RREB1; CCNE1; AES; NR0B1; SOX9; SP140; MYBL1; SALL1; MSX1; INSM1; OSR2; HHEX; FOXL2; NR1H3; E2F3; FOXF1; FHL2; DLX5; NFKB2; HDAC1; JUNB; ZNF91; HES1; NAB2; OLIG2; EN1; ST18; MEIS1; TFAP2C; TBX3; MNDA; GATA6; ZNF652; DAXX; PBX1; TRIM32; PAX6; NR4A3; EGR3; NFE2L3; IRX5; KLF10; TGIF1; ZBED1; PBX3; HOXB7; SNAI2; SPDEF; DACH1; FOS; ERBB4; ZNF331; NFATC3; NR2F1; NR4A2