Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76780	Afatinib	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	ASH2L; PHF8; TAF10; PCBD1; BTG1; ZNF672; MNAT1; MED7; PTTG1; HCFC2; PIAS2; KLF12; NRBF2; ZNF274; YEATS4; ZNF528; HDAC6; TSC22D3; FOXO1; GLI3; TTF2; THAP1; TRIM29; BRF2; MDM4; LITAF; CEBPG; FOXO4; NFE2L1; ZEB2; PMF1; MAZ; PDLIM1; PRKDC; AEBP1; TCERG1; TRIM22; ZNF226; ARID4A; ELK1; BRD8; RBM14; MMS19; KDM5A; SPIB; HSF2; CITED1; PPARGC1A; TAF4; BRD2; ARNTL; MTDH; PSMC3IP; USP22; GTF2A1; BMI1; POU4F1; TBP; TMF1; HOXC6; NR2E1; MLXIPL; NFYC; MYB; UBE2I; RERE; NEDD8; MYNN; MED20; SMAD5; RXRA; ETV1; BAZ2B; NRIP1; HLTF; ZNF140; ZNF32; SMAD1; KAT6A; USF2; TAF7; ATF5; RFX7; TRAK1; CREB3L1; PCGF2; NR1I2; FOXD1; CREBZF; BNC2; FOXN3; PTRF; BASP1; KLF6; PHF2; SUV39H1; RFX5; MAGED1; SREBF1; BBX; CRY1; BRCA1; TP63; TBPL1; ZBTB18; EMX2; IL16; SP2; MYCBP; NUP62; KLF2; MED24; VEZF1; EED; STAT6; STAT1; CTR9; ATF2; CDK9; SAP18; SMARCA2; MED1; COPS5; TAF11; BAZ1A; PATZ1; BRD4; NELFB; LPIN2; BIRC2; DNAJC1; NCOR2; TCF21; RUNX1; RNF14; SUB1; ATF1; HTATIP2; TCFL5; JUND; AFF1; RNF6; PIR; PAX5; SIX1; RHOA; IKBKAP; PSIP1; TOX; TWIST1; ID3; SNAI2; HOXB7; LEF1; JUP; CRK; ARID4B; ZHX2; KDM5D; TLE1; ESR1
Down-regulation	129	MYC; ZNF611; ZNF512B; REL; SOHLH2; JUN; ZNF160; NKX2-2; NFKB2; SMARCA1; TAF1A; ZNF711; RREB1; NFE2L2; ZNF264; TLE2; FOXF2; BCL11A; NFE2L3; ZBED2; ZNF586; NKX2-1; KAT2B; ZNF22; ZNF721; GRHL2; ZNF623; MNDA; ELK3; ZNF124; ELF5; ZNF239; SSBP2; AHR; ZNF74; TFAP2A; NCOA1; FOXC1; TFAP2C; LIN28A; BACH1; ZNF573; ZFP36L1; BCLAF1; DNAJC2; DLX4; ELF3; THAP4; ZFHX3; NEUROD1; WWC1; NFAT5; IKZF1; URI1; VGLL1; SRCAP; NFKB1; TGFB1; SMAD6; HOXA5; DLX5; FOSL1; ETV4; SMARCD3; HIC2; NR4A3; RBFOX2; HOXB2; BARX1; HOXB5; ETV5; XBP1; PRDM1; ERBB4; TCF20; HMGA2; MGA; CBX4; ID4; FOXF1; HIRA; OSR2; SP3; HEY2; ID1; PAX6; CREB3L2; ZNF443; SATB2; ZNF43; TCF7L2; NR4A2; EN1; NANOG; KLF4; TRPS1; EYA1; ZNF331; TBX3; PHIP; ZFPM2; MYT1L; ZXDC; ZNF652; ZNF217; WWTR1; CREG1; FHL2; CREM; HHEX; MEIS2; ZNF117; NAB2; IRF8; SOX9; ZBTB20; HES1; ZBTB16; BHLHE41; MEIS1; DACH1; DMTF1; FOS; NFATC3; MYBL1; WT1; ZNF423; DAXX; SATB1