Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76779	Azd-5438	GSE92742	MCF10A	Human	6h	0.08uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	PCBD1; KLF12; TAF10; SMAD7; TCERG1; GLI3; THAP1; ZNF528; TGS1; PIAS2; PPRC1; ZNF593; KAT5; HDAC6; YEATS4; FOXO1; SKIL; ZNF222; AFF4; PHF8; NPM1; PAX8; LYL1; PRKDC; SAP18; MYNN; BRF2; ASH2L; STAT5A; ETV1; FOSL1; CBFB; NUP62; GATAD2A; NCOR2; ADNP2; ATF5; ZNF473; POLR3F; UBE2I; HSF2; NRIP1; MLXIPL; TAF4B; ZNF24; FOXN2; AEBP1; RBM14; ZNF195; MAFG; HDAC9; WDR77; SMAD1; ZNF432; STAT6; TRIM22; PAX5; PMF1; HMBOX1; ZNF426; MEOX2; ZNF263; ZNF136; TP53; USP22; ANKRD1; CEBPG; MAFB; SALL2; MAFF; CRY1; ZNF337; RRN3; SSRP1; BNC2; PTRF; EMX2; BACH2; TGFB1I1; FOSB; CREB3L1; ERBB2; ERG; MLXIP; MED1; SUB1; ZNF83; CTR9; NKX3-1; RUNX1; ZNF140; SF1; RBBP8; PCGF2; EGR3; XBP1; E2F3; CREB5; ZNF32; TOX; ZFP36L1; ASCL1; ZMYM2; CITED1; RLF; ZBTB18; TBP; EGR2; MED24; PITX1; MSX1; IKBKAP; HEY1; FOS; FOXO3; ETS1; KLF7; IRF8; INSM1; SHOX2; SIX1; SOX17; ISL1; HOXC6; CRK; ZIC1; ESR1
Down-regulation	157	BCL11A; TOB1; TBL1X; NFE2L2; KAT2B; TOX3; ZNF184; CDYL; MYCL; ZFPM2; PNRC1; AHR; CDK2; NFKB2; MNDA; TFAP2A; ARID4A; PSMC3; RREB1; ZNF652; ZNF264; SAP130; ZNF512B; ZNF586; PMS1; TRIM24; RAD21; ZNF623; ZNF611; JUN; ZSCAN31; REL; ZBTB38; ZNF148; SFMBT1; BASP1; NFE2L3; FOXF2; TFDP2; BACH1; PHF20; DBP; MGA; ELF2; SOHLH2; TULP4; GATA6; VGLL1; GRHL2; CREB3L2; HMGB2; NCOA1; CHD9; OSR2; CBX4; TGFB1; DEAF1; TAF6; HHEX; ATF7IP; TAF12; CREM; ID1; TAF9B; NCOA6; MEIS1; CBFA2T2; KLF4; ZXDC; PKNOX1; NKX2-1; ITGB3BP; PBX1; SP3; HOXA5; ARID3A; NR4A2; ZNF33B; HOXB6; WNT4; PAX6; TFAP2C; ZNF331; WWTR1; UBE2B; MEIS2; MXI1; ZNF248; PRDM1; TGIF1; TXNIP; ZFP64; URI1; MAF; TCF4; ZNF160; FOXC1; ZMYND8; TDP2; ZNF467; BRD8; MYCBP; NR2F1; DAXX; TLE2; DACH1; WWC1; SAP30; DEK; MYBL1; DNAJC2; PHIP; ING2; CREBL2; KLF11; HOXC10; ARID5B; HIRA; FOXF1; FLNA; LIN28A; AES; CTNNB1; HIC2; RBPJ; IRF7; HSF1; PBX3; CBX7; NR1D2; HMGN3; ERBB4; AFF1; PLAGL1; NFAT5; NFATC3; HLF; MKL2; HOXB7; ID2; ELF3; RBL2; TBX3; NFIB; NFIL3; KLF9; HOXB2; DMTF1; KLF5; RORA; ZEB1; SOX9; TLE4; ID4; PSIP1; SATB1; CITED2