Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76777	Azd-5438	GSE92742	MCF10A	Human	6h	2uM	EID0441

Response Information :

Types	Number	Response transcription factors
Up-regulation	176	VGLL4; TAF10; ASH2L; MDM4; PCBD1; HMG20A; LZTS1; ZNF143; MAZ; PRKDC; TRAF6; MAGED1; TCERG1; CTR9; NRBF2; TRRAP; KAT8; CAPN15; ZNF211; GATAD2A; RELA; MLX; NUP62; SATB2; ZNF516; PHF8; NFE2L1; MAFG; ZBTB43; PAX8; AFF4; THAP1; ZNF8; NCOR2; HEY1; FOSL1; GMEB1; LYL1; ELK1; PCGF1; ZNF222; ADNP; MNAT1; SMAD1; AATF; ZNF408; PEX2; MED1; NR1I2; FOXN2; SAP18; MAFB; ZNF83; MED17; PPRC1; HOXC8; PIAS2; BAZ1A; GFI1; E2F3; BCL10; PMF1; ZNF24; HAND1; UBE2I; ZNF669; HDAC6; ZFHX4; CUX1; BAZ2A; ZBTB18; NR2E1; SMAD7; EGR4; PPARGC1A; ADNP2; ZNF274; ZNF562; ZNF195; ZNF468; FOXG1; SOX21; TBP; RUNX1; KLF7; GLI3; RBBP8; ZKSCAN1; HDAC9; SCAND1; TERF2; BRF2; POLR3F; MTF2; CRY1; FLI1; KAT6A; SP2; CREB3L1; AGO2; SUB1; ZBED2; HSF2; NR1H2; UBE3A; MSX1; KDM2A; PLAGL2; RFX7; MYB; SUV39H1; USP22; CREBZF; HMGB1; SALL2; THRAP3; ERG; INSR; ZBED4; GABPB1; BCOR; AIP; SIX1; MYCBP; KMT2B; TFCP2; SOX9; ANKRD1; FOXO1; ASCL1; ZNF266; TAF9; EGR3; FOXO3; KLF13; NPAS2; SIX2; CREB5; AEBP1; CITED1; PBX3; CHD7; ZNF32; ZMYM2; MED24; TLE4; STAT1; TFAM; TBPL1; RFX5; ZNF629; ZSCAN18; HMGB3; ZNF91; MLXIP; MED13; ZNF432; RRN3; EGR2; SNAI2; MNT; TFEB; IRX5; CUX2; ZNF7; CRK; KDM5D; RHOA; EYA1; IKBKAP; NRIP1; ISL1; NKX3-1; TSC22D1; FOS; HOXC6
Down-regulation	150	KAT2B; TFAP2A; FOXF2; CCNA2; TOX3; ZFPM2; TCF25; NFE2L2; SMARCA1; AHR; ZSCAN31; CREM; GRHL2; MNDA; ELF5; NFKB2; JUN; BASP1; HMGB2; EHF; ZFHX3; CREBL2; TBX21; TULP4; CDK2; GATA6; SP140; HOXB6; FOXM1; PAX6; CAMTA1; MYBL1; TEAD3; ZBTB38; RUNX3; TRIM16; NKX2-2; OSR2; TLE2; HOXB7; BANP; ZNF512B; PEG3; PAWR; RREB1; TAF1A; REL; NR4A2; NR2F1; ZFP36L1; CARHSP1; TOB1; HHEX; ZNF239; TFAP2C; WWTR1; NR4A3; MEIS2; ZNF611; ZNF586; BCLAF1; AR; DEK; ZBTB20; ZNF536; E2F8; CHD9; ZZZ3; TFDP2; TBL1X; PHIP; KLF4; BCL3; HOXB2; ARID5B; NEUROD1; DAXX; ZNF331; ZNF160; UBE2B; STAT4; ZXDC; EPAS1; LIN28A; URI1; VGLL1; HOXD3; TGIF1; ZIC1; TRPS1; PBX1; NR1H3; HOXA5; NFE2L3; NKX2-1; NR4A1; CENPF; RB1; ERBB4; NR5A2; NR1D2; HOXB5; ZNF148; HBP1; ZNF248; HLF; FOXF1; FOXE1; MECOM; SOX10; PHF20; ZMYND8; WWC1; IRF1; TCF4; NR3C2; MEIS1; ST18; FOXC1; HOXD1; SMAD6; CRYM; ITGB3BP; HIRA; PITX1; AES; NFAT5; SIAH2; MYRF; BHLHE41; NFIL3; RBL2; CITED2; ELF3; ZBED1; CREB3L2; POU2AF1; TBX3; IRF4; SOX17; CTBP2; HES1; JUP; CREB1; ID2; ESR1; TBX2; CEBPA; RORA; ATF3