Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76756	Canertinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	141	TRPS1; TCF25; ZNF623; EMX2; ESR1; NR5A2; HIF3A; ATOH1; ZSCAN31; TFAP2C; ST18; MEIS2; FOXI1; PEX14; CERS4; RING1; THAP10; PRDM2; PCGF3; GATA6; TULP3; TEAD3; HOXD13; SIX6; HLX; ARID5B; TSC22D3; HOXD3; ZBTB17; CRYM; MEIS1; TCF7L1; BCL11A; GRHL2; LOXL2; NEUROD1; CITED2; LEF1; SUPT3H; OSR2; CDK2; ZEB1; PRRX1; HOXD11; HOXD1; AR; TGFB1I1; PRPF6; RBFOX2; NR4A2; IRF9; FOXF2; SP140L; WNT4; ZFPM2; ZIC1; NHLH1; ZNF74; TERF1; CDIP1; IRF6; GTF2F1; MAML1; FOXF1; TCF7; FUBP1; ATF3; PBXIP1; PBX1; CTNNB1; HOXB13; ZNF467; NCOA2; FOXN3; THRA; NFATC4; BNC2; BCL6; NFKB2; SSX1; MYRF; ERBB4; SPIB; JUP; PAX6; PSMC3; BACH2; TLE2; SOX2; ID4; RBPMS; SOX17; PHIP; ACTL6B; ARNT2; HDAC9; E2F8; CUX2; IRF4; SOX13; JUN; INSM1; DLX2; PNRC1; DLX5; HOXA11; NFE2L2; IRF7; LIN28A; HOXB2; MAF; CDK9; TCEA2; RAD21; ZNF232; DACH1; CITED1; ZNF93; TGIF1; RB1; SSBP3; SALL2; WT1; PAX5; SMARCD3; ZNF611; TRIM29; KAT2B; AEBP1; HOXA10; NR2F1; ZFP36L1; POU2AF1; ZSCAN18; SOX11; NFE2L3; ATF5; PEG3; ZNF331; PSIP1; ZNF91
Down-regulation	207	FOSL1; CRK; MYC; CTR9; PPRC1; TSC22D2; GATAD2A; NELFB; TAF10; NFKBIA; RBBP5; IKBKAP; ZBTB7A; ZBED4; MYCBP; SOX15; YWHAB; DNAJC2; ELK1; TRIM32; FHL2; NUP62; GFI1; BAZ1B; TFEB; RBM14; NKX3-1; ARID3B; SMARCA4; PSMC3IP; MTF1; WWC1; ZNF267; KDM5D; ZBTB11; TCERG1; ELK3; CBFB; CEBPZ; SIX2; ASH2L; ADRB2; SMARCA5; PTRF; KLF10; ZBTB43; BAZ1A; ADNP2; NRBF2; SIX1; ZNF614; MBD2; MAZ; TSG101; NR2F2; TTF1; BRPF1; KLF12; RNF6; ZHX3; NFYB; ATF1; EED; PPARG; ABL1; DDX5; BCL3; ZNF23; ARNTL; MED6; MED1; PURA; ZBTB38; BCOR; MNT; ZNF143; HNRNPD; E2F3; SIM2; MAFG; CSDE1; CHD1; TBP; ZNF281; NFIB; TRAK1; ZBTB1; SMAD7; PIAS3; NFATC3; BMI1; TFCP2L1; MLX; TCF12; CCDC59; EGR1; KDM5B; ING2; HIPK3; RFX7; TAF1D; FOXC1; MAGED1; BIRC2; SUV39H1; RNF10; BASP1; YAF2; GTF2IRD1; TRIP6; CARM1; REST; TFAM; MTA1; CREB3L1; USF2; RHOA; PCGF2; THAP1; CNOT2; SKI; HDAC1; TSC22D4; SNW1; PIAS2; PDLIM1; AFF1; NRIP1; FOXD1; XBP1; DDX54; JARID2; DNAJC1; SOX9; TFE3; SFPQ; RNF14; TRIM28; HLTF; CREB5; RUVBL2; RNF4; CHD7; STAT6; DR1; SAP30; SMARCE1; BAZ2A; ZNF165; SUB1; IRF1; ZNF410; RCOR1; ORC2; ETS2; ERG; ZMYND8; VEZF1; SMAD5; PRKDC; KLF7; KDM2A; SMAD1; RUNX1; ID1; NCOA4; ZMYM2; ZNF652; BRD3; BBX; CRY1; MXI1; ECD; NR1D2; FOXJ3; HTATIP2; NCOR2; GABPB1; ATF4; MAFF; RFX5; ELF5; SPEN; HMGA2; KLF6; MAFB; ZBED2; JUNB; TGFB1; MNAT1; HSF2; KLF5; TP53; DAXX; TOPORS; GTF3A; HOXC6; TBL1X; SERTAD2; FOXO1; MSX1; TCFL5; ELF1; ERBB2; KAT6B; TXNIP; MYBL1