Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76755	Canertinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	GATA3; TRPS1; SOHLH2; NCOA2; NAB2; SUPT6H; CBX4; GLI1; ZNF623; TEAD3; HIF3A; TRIM24; TERF1; GTF2F1; NFKB2; PRPF6; ARID5A; BHLHE40; ZSCAN31; ERBB4; CREM; TCF25; TCF7L1; IKZF1; AR; ELK4; HABP4; E2F6; PHF1; NCOA1; NR1H3; HINFP; ZNF74; EMX2; SSBP2; ATF3; ZNF239; KDM4C; RING1; ZNF44; SCMH1; ZFPM2; TSC22D3; TLE2; HIC2; CBFA2T3; SSX1; E2F2; FOXJ2; MED12; WNT4; PAX6; THAP7; PEX14; HSF1; GRHL2; CEBPA; RREB1; PRDM2; DACH1; ZNF133; MLLT10; ARID5B; PNRC1; LIN28A; PRMT2; TAF12; ZNF331; ATN1; HDAC5; PLAGL1; MED15; OSR2; EN2; IRF6; SOX3; ITGB3BP; CDK2; FUBP1; RBBP8; FOXF2; PRDM1; SUPT3H; ZNF423; ESRRG; IRF4; CAMTA2; ZNF467; NFE2L2; E2F8; PEG3; BANP; TFAP2C; PBXIP1; ESR1; HLF; PREB; LZTR1; CBX7; DAXX; NR4A3; CREBL2; BCL11A; TBL1X; HIRA; SMARCA1; RBFOX2; SPIB; CTNNB1; TAL1; LEF1; MECOM; MEIS2; ZNF512B; ZBED1; POU2AF1; NANOG; NR1H4; PHF20; ZBTB20; CITED2; KAT2B; JUN; CERS6; ZNF611; SATB1; ZEB1; NR2F1; PBX1; CITED1; SMARCD3; FOXF1; DLX5; SSBP3; PHIP; TCFL5; HOXB7; TRIM16; ZIC1; FOXJ3; NR4A2; MEIS1; BHLHE41; SIAH2; TRIM29; TCF4; ERBB2
Down-regulation	209	FOSL1; FOS; MYC; CBFB; ARID4B; SNAI2; SIX2; ZBTB18; ETV1; NFKBIA; PPRC1; NELFB; MLX; LITAF; TCERG1; BAZ1A; MDFI; NKX3-1; SOX15; TFAM; ZNF672; SAFB; ASH2L; ZNF24; TSC22D2; TBPL1; ELK1; GATAD2A; SIX1; ZBED4; CCDC59; ZNF146; FOSB; CHD9; CEBPZ; ZNF669; HSBP1; ADRB2; PA2G4; SMARCA4; CENPF; SMAD4; ZNF23; SMARCE1; ZNF107; ETS2; BLM; BAZ1B; SMAD7; CNOT1; BTAF1; ZNF614; SKIL; RYBP; MYRF; MED13; UBE2I; ZBTB7A; JUNB; HES1; GTF2A1; NR1I2; THAP11; SFPQ; CHD7; ZNF528; RUNX1; DEK; MED1; FOXO3; PMF1; TTF1; TRAK1; EGR1; ZSCAN12; BRF2; TRIP6; BRPF1; ACTL6A; MNX1; NCOA4; HCFC2; MYNN; KLF7; RFX5; CREB3L1; HMBOX1; GABPA; SPDEF; ATF1; ETV5; SF1; KMT5A; CRK; SIM2; TBP; TAF1D; USF2; BRD7; FOXA2; ILF2; WDHD1; HNRNPD; ABL1; PATZ1; IFI16; ARNTL; ZNF131; HMG20A; MAZ; TEAD1; AATF; WDR77; SMAD3; SAP30; SSRP1; EHF; BCOR; SP100; YEATS4; HDAC1; PRKDC; SMARCC1; YWHAB; RFX7; HOXC10; ZEB2; MTA1; CRY1; TFAP2A; RNF141; BRD3; SMAD2; ORC2; SHOX2; MAFF; RBBP4; PEX2; TAF10; ZNF532; PBRM1; E2F3; PBX3; TP53; NFIB; SUV39H1; RRN3; ZNF432; RARA; ECD; ZBED2; GABPB1; SP110; HDGF; ZNF84; YAF2; BMI1; KDM2A; TRIM28; NFAT5; KLF5; PTTG1; BTG1; ISL1; ASCL1; BRIP1; ELK3; ZNF32; ELF5; RBPJ; NR2F2; NUP62; TRIM22; TMF1; ZNF217; C1D; PDLIM1; SPEN; SMAD5; ERG; XBP1; HSF2; HMGB1; MED24; GTF3A; ZNF652; KDM5D; NRBF2; HMGA2; HEY1; HOXA10; HOXC6; CARM1; MAGED1; FOXD1; MXD1; JARID2; ID3; TOPORS; MEOX1; ZMYM2; MLXIP; TXNIP; IRX5; SOX9; NR1D2; ID1; MSX1; BASP1