Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76754	Canertinib	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	163	TFDP2; CNBP; ZNF623; SOHLH2; KDM4C; GRHL2; MNDA; HAND1; ADRB2; NR4A2; TCF7L2; GATA6; CD3D; ATF3; HMGB2; ZBTB20; ZXDC; CBX4; TRPS1; INSR; RNF138; HIF3A; ZNF44; HBP1; ZSCAN31; RXRA; TRIM24; FOXN3; KDM5B; NFKB2; PNRC1; FOXE1; CBX7; WWC1; TCF7L1; PIAS4; HHEX; ZFPM2; TSC22D3; AR; TFAP2C; KLF11; SETDB1; KLF9; KLF4; ATN1; WIZ; PBXIP1; DBP; ZNF331; LIN28A; PAX6; WNT4; ZNF239; YAP1; CBFA2T3; TERF1; MXI1; PCGF3; IRF7; TLE2; ST18; SSX1; NR5A2; ZNF74; IRF6; CERS6; ZNF264; NR2C1; NEUROD1; THAP10; CBFA2T2; NKX2-1; CSDC2; HIPK1; RORA; TCF7; CITED2; NR3C2; CERS4; CREBL2; ZNF136; ZNF688; PRDM2; AEBP1; CDIP1; RAD21; MYCL; MKL2; CIZ1; ZNF83; HSF1; OVOL2; MYT1; FUBP1; ARNT2; ITGB3BP; DEK; NCOA2; ZNF160; SOX2; URI1; TBX3; AES; SOX11; NFE2L3; PEG3; NKX2-2; MYB; SUPT3H; ZNF611; ZNF43; ZNF91; ZNF117; LMCD1; SSBP2; HLTF; OSR2; NANOG; HOXB6; CREB3L2; NFE2L2; HOXB7; NR4A1; TFAP2A; TCEA1; ZEB1; STAT1; MEOX2; TGIF1; BTG1; DNAJC1; ARID5B; MAFB; IRF9; HMGN3; MTA1; FOSL2; ZIC1; DLX2; PHIP; DLX5; WT1; SMARCA1; ERBB4; FOXJ3; CCNH; RBBP8; INSM1; TRIM16; KAT2B; CREG1; NR1D2; TOX3; SALL2; HIC2; RB1; JUN; CREB1; ATF5; ID4; MEIS2; ZSCAN18
Down-regulation	184	TRIP6; TFEB; MYC; FOSL1; FOS; HMGA1; RELA; ELK1; ETV4; ETV1; TSC22D2; EYA1; DNAJC2; HIVEP2; C1QBP; ESRRA; HDAC6; BLM; ASH1L; ETV5; MLX; BAZ1A; ZNF672; KDM5D; CREB3L1; MDFI; RNF4; GATAD2A; GMEB2; PPRC1; BASP1; EGR4; TAF10; CRK; STAT6; NFKB1; TRIM27; MAZ; ZBED4; RNF111; ERCC2; LITAF; CBFB; SOX15; MED20; SIX2; TGFB1; RUVBL2; TCERG1; BRPF1; ID2; EGR3; RYBP; SMARCA4; CTR9; MECOM; FHL2; MBD2; SALL1; MAFF; GTF2IRD1; TBPL1; SATB2; GABPA; ZNF432; MSX1; BRD8; CRYM; EZH2; UIMC1; EGR1; PHF8; ZNF384; NRBF2; WDR77; UBE3A; KLF7; CARM1; SMARCD1; HES1; TFE3; NFKBIB; ZMIZ2; CEBPZ; ELK3; MTA2; PTRF; KDM5A; YAF2; RBM14; PPARG; CHD3; TADA3; ASH2L; REST; DDX5; ECD; SMAD7; IFI16; ZNF410; ERG; RFX7; PA2G4; TLE1; SMAD3; LYL1; TSC22D4; BRD2; TLE4; CUX1; SUV39H1; NUP62; TRIM29; BCL10; PIR; YBX1; TRIM28; SMAD1; PDLIM1; SMAD5; SPEN; NPAS2; BCL3; TSG101; CREB5; USP22; MED13; TGIF2; MTDH; FOXA2; YBX3; CHD1; YWHAB; TTF2; TAF1D; MAFG; ARNTL; PIAS3; HOXA11; SNAI2; PAX5; GLI3; GABPB1; TFCP2L1; TRRAP; ZNF562; USF2; NAB1; SATB1; CCDC59; RUNX1; KLF5; ZBTB38; RBPJ; PIAS2; HSF2; FOXO1; KAT6B; HEY2; C1D; ORC2; KLF10; ZNF516; MAF; ZBED1; TP53; HOXA10; CHD7; SIX1; ZBTB18; NR2F2; NFIB; SHOX2; ZMYM2; MNAT1; STAT3; MAGED1; MEOX1; MED1; MLXIP; DAXX; ELF1; RUNX3; PITX1