Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76753	Canertinib	GSE92742	MCF10A	Human	6h	10uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	TRPS1; PKNOX1; MNDA; ZXDC; ZMIZ1; ZNF34; NFKB2; HOXA3; HAND1; CBX4; DLX4; TSC22D3; JAK2; PNRC1; NR4A2; RAD21; PRMT2; FOXJ2; TBX2; COPS2; HOXD13; RARG; NEUROD1; HINFP; HDAC5; PHIP; NR0B1; NFE2L2; TULP3; EN1; CAMTA1; NFIL3; SSBP2; HOXB13; RING1; FOXF2; ILF2; DBP; SOHLH2; ZNF331; GTF2F1; YBX1; NR2F2; FOXD1; TOB1; JUP; THAP10; SUPT3H; NR4A3; ZFPM2; CREB3L2; HIRA; THRA; IRF8; ZNF124; NR1H4; SREBF2; MAF; FOXJ3; ZSCAN31; KLF9; PRDM2; GATA6; TLE2; PAX6; INSR; KAT2B; ACTL6B; RXRA; CBFA2T3; CREB1; IRF6; NKX2-1; ST18; BCL11A; SSX1; SPIB; PSMC3; SAP30; IRF9; STAT1; E2F8; NKX2-2; MYBL1; MYCL; ENO1; ARID5B; ATF3; JUN; INSM1; PEG3; TXNIP; ZBTB38; ELF5; HMGN3; EGR2; TBX3; SHOX2; MAGED1; IRF4; WT1; ZEB1; RFX5; ERBB2; BHLHE41; ZFP36L1; HIC2; ZBED2; ZBTB16; HHEX; NR2F1; MEIS2; TCF21; ZNF512B; MEIS1; TRIM22; ZIC1; ZNF91; ID4
Down-regulation	202	FOSL1; MYC; LOXL2; ZNF3; SOX15; NELFB; LITAF; BLM; RELA; TSC22D2; ELK1; TAF1D; ETV1; ZNF24; TSG101; MDFI; E2F3; RUNX1; MECOM; HDAC6; MYCBP; MLX; ZNF107; CTR9; ZBTB7A; BCL10; GTF2IRD1; UBE2I; MYBBP1A; ZNF468; ADRB2; TCERG1; REST; NPAT; KDM5B; TFEB; CHD7; ASH2L; STAT6; RBBP5; PPRC1; KLF2; TOX; POU5F1B; NUP62; RNF14; GATAD2A; MTF1; SMAD1; NRF1; VPS72; PHF8; SIX2; ELK3; ZMYND11; UIMC1; CBX3; TRRAP; NFIB; EGR1; JUNB; SMARCD1; ZNF672; HIVEP2; MYRF; LHX2; GATA3; SFMBT1; PPARG; TCF12; TRIM27; TAF4; E2F5; SMARCB1; PSMC3IP; ADNP2; AIP; WDHD1; LYL1; HDAC3; GTF2A1; KLF12; ZNF552; IRF2; PATZ1; DDX5; USF2; ZNF200; MAFF; ORC2; FOXO1; MED7; SETD2; BAZ1B; CEBPZ; YWHAB; KAT6A; WDR77; GLI3; BCOR; ZFP64; TAF10; ZNF165; ZEB2; ZNF532; SUV39H1; PCGF2; NAB1; CTBP1; ETV4; PDLIM1; PRKDC; CCNH; MBD4; HIPK3; FHL2; SMAD6; LPIN2; ZNF516; TRIP6; CREBZF; SOX13; ISL1; FOSB; CTNNB1; TSC22D4; PMF1; SMAD3; BMI1; SMAD7; TFE3; IL16; BAZ2B; CALR; PIAS2; HDAC1; NRIP1; VEZF1; USP22; CRK; RNF4; CSDE1; CENPB; NLK; ECD; HOXA11; TBP; DDX54; MGA; RBBP4; NR1H2; BIRC2; BCL3; SPDEF; NKX3-1; CBFB; BAZ1A; PEX2; EMX2; SMAD5; RBL2; ZNF232; ZKSCAN1; ZNF23; ZNF652; TGIF1; ZNF143; SCAND1; ZNF432; RARA; BRPF1; EGR3; ELF1; KAT6B; TP63; PBX1; ESR1; IFI16; AATF; TSC22D1; HOXA10; ASCL1; MNAT1; PIR; NCOA3; MTA1; TP53; ZMYM2; RBBP8; TGFB1; ATF1; STAT3; SATB1; HOXC10; FOSL2; FOXC1; TCFL5; TLE4; MSX1; KDM5D; HOXA5; ID1