Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76745	Olaparib	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	168	TRPS1; SSBP2; HOXD3; GATA6; TBX21; PCGF3; DMTF1; MNDA; CBX4; KLF10; NFKB2; ZBTB20; TEAD3; NEUROD1; ZNF623; SMAD6; HES1; ZFHX3; ZNF239; ZMIZ1; TULP3; TLE2; MECP2; EYA1; RBFOX2; ATOH1; PHOX2B; ZNF175; BCL11A; SOHLH2; THAP10; E2F2; SCMH1; SIRT7; HMGB2; RING1; SND1; RARG; SMARCA1; TCF3; ZSCAN31; AR; PFDN5; FOXF2; FOXF1; EZH1; MBD1; TAF1C; IRF1; ZNF816; BCL6; NHLH2; NR2F1; MEIS2; EN1; TAF5L; CALR; SOX5; MXI1; ZXDC; KLF9; TBX3; TAF6; ZNF573; ACTL6B; TGFB1I1; CREM; SLC2A4RG; CREBL2; ZNF443; ZNF500; ZNF44; INSM1; HHEX; VGLL1; SMARCC2; ZNF423; SPIB; RAD21; TERF1; ETV5; GRHL2; PAX6; ZNF74; PRDM14; CITED2; SUPT3H; NR1H4; ID4; LIN28A; ITGB3BP; ZIC3; MYT1; CREB1; ZNF467; NKX2-2; ZBED2; CREB3L2; MED15; CSDE1; BHLHE41; ZIC1; CBX6; ZNF331; CBFA2T3; ZNF415; ESR1; ZNF304; ERBB4; KAT2B; HIRA; WT1; ZFPM2; BHLHE40; IRF9; AES; PRRX1; NPAS2; ZMYND8; HOXB13; RBPJ; PRDM2; NR3C2; PEG3; HDAC9; MAF; EYA2; DLX5; SPDEF; TOX; NFE2L2; OSR2; DAXX; ISL1; ZNF611; HIC2; ZFP36L1; UBE2L3; IRF4; POLR3C; SNAI2; CALCOCO1; ZHX2; WWTR1; TFAP2A; TOX3; IRF8; MEOX2; ZBED1; KAT6B; TCF4; SSBP3; JUN; FOXJ3; MYCL; MTA1; BCLAF1; SATB1; BCL3; TBL1X; RB1; TRIM22; NR4A2; ZEB1; ZSCAN18; DLX2; TCFL5; PITX1
Down-regulation	205	CRK; CTR9; TRIP6; FOSL1; TCEA2; FOS; CENPF; CCNC; C1QBP; FOSB; TFAM; NELFB; RBPMS; TCF7L1; EZH2; NPAT; GATAD2A; SMARCA5; BAZ1A; MYBBP1A; MLXIPL; ERCC2; HDAC6; SAFB; WWC1; IRX4; NFIB; MED4; ETV1; PRKDC; RBBP5; ASH2L; TBP; ASXL1; PRPF6; RLF; SOX15; BLM; MED6; LITAF; ZFP36L2; ZNF672; PTRF; SMAD3; PCGF2; TRIM16; FOXN2; SIRT2; TAF10; DDX5; PMF1; CREB3; SP2; HTATIP2; BRCA2; KLF2; ELK1; TSC22D3; RNF111; PUF60; EGR1; PPP1R13L; GABPA; SOX4; SREBF1; RBL1; PPRC1; HIPK3; NUP62; WDHD1; MSX1; TLE1; NKX3-1; TSC22D2; VPS72; TP53; SMARCA2; NFYB; BASP1; PSIP1; TAF1D; FOXO4; FOXO3; ARID4B; PPARG; RUVBL1; TLE4; TADA2A; ZNF146; NRIP1; TMF1; CCNH; MED1; ZNF165; ZNF143; BRD8; RHOA; TCF12; RBM14; SETD2; CEBPA; OLIG2; KLF6; ZMIZ2; REST; TCERG1; YAF2; MED24; LPIN2; GTF2IRD1; MED27; ATF1; ZBTB18; CHD7; KDM5B; ELK3; PATZ1; ZBTB38; BIRC2; KAT7; MLX; HNRNPD; JUND; WDR77; RFX5; PSPC1; DNAJC1; AATF; RUNX1; NCOR2; NFIL3; NLK; ATF5; PDLIM1; SMAD5; HMGB3; NRBF2; YAP1; RFX7; TAL1; TRRAP; ID3; LYL1; HOXA7; CRY1; FHL2; CEBPB; TOB1; VDR; ARNTL; DEAF1; E2F3; FOXD1; YWHAB; PHF2; ELF1; NCOR1; RNF141; SPEN; ZNF426; PIAS3; CBFB; AFF1; FOSL2; ETS2; ZNF430; HOXA10; BRD4; SCAND1; TSC22D1; MEOX1; SATB2; ZMYM2; ZBTB11; STAT3; MNAT1; YEATS4; ZNF281; ABL1; MAGED1; TEAD1; PREB; SUV39H1; ENO1; ELF3; BRIP1; ERBB2; CREB5; TRIM29; USP22; PTTG1; HMBOX1; FOXO1; HSF2; ZNF274; BAZ2B; ZKSCAN1; HEY2; PBX3; CREG1; ID1; TFCP2; SOX9; HMGN3; TXNIP