Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76744	Olaparib	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	PITX2; TRPS1; TAF5; FOXF1; CNBP; NFKB2; RXRG; JAK2; NKX2-1; NR4A2; CSDC2; BHLHE41; ZNF16; FOXE1; MYT1; HSF4; NEUROD1; CAMTA1; ZHX2; INSM1; CITED1; ZFPM2; MEIS2; ZNF33B; PSMC3; FOXM1; PIAS4; BNC2; HIRA; WWC1; GATA6; MAF; NR5A2; NR2F1; HDAC5; ZNF93; SMAD4; TDP2; ZNF74; ZNF253; ZIC3; CIZ1; IRF8; RAD21; CBFA2T3; NCOA2; PRDM2; ZBED2; SUPT3H; ATF4; ZNF239; ATF3; SOX10; NR4A1; PRRX1; TGFB1I1; HMGB2; MYCL; EGR3; ZEB1; ZNF248; MNDA; E2F8; POU4F1; NFE2L3; BCL11A; MTA1; SOX11; ARNT2; SOX13; SOX2; CREB3L2; PBXIP1; MYB; NFE2L2; RB1; HHEX; EGR2; ZBTB18; ZNF331; PSPC1; RBBP8; TOX; ABL1; CDK9; ZFP36L1; BACH2; BRD3; PFDN5; HOXC10; JUN; ZNF131; ZNF665; TLE2; ERBB2; OSR2; PBX3; TBX3; ZIC1; ERBB4; POU2AF1
Down-regulation	147	GTF2A2; JUND; TCEA2; VPS72; TSC22D2; CTR9; LITAF; MLXIPL; MECOM; PKNOX1; TAF10; NFAT5; SMAD1; ZBTB7A; ZNF574; CEBPB; NFATC3; MAZ; ASH2L; TMF1; BBX; TOB1; NFE2; STAT6; REST; ZBTB11; FOXA2; BCL11B; SMARCD1; YWHAB; CCNC; TLE1; BMI1; PPARG; TFAM; PRKDC; SAP30; MED13; BRF2; PMS1; TSC22D4; NR3C1; RBL2; HIPK3; TGFB1; SMAD5; MSX1; ATF1; SIN3B; ZNF432; LPIN2; CRK; TCERG1; VEZF1; BCL3; NR2F2; TAL1; KLF7; SIX2; TCF12; SNAI2; ID1; ZNF562; SETD2; ZNF467; NUP62; ZFP64; TFCP2L1; THAP1; BAZ1B; ERG; CITED2; HTATIP2; ADRB2; BRD2; TRIP6; C1D; BTG1; CHD9; TP63; GATAD2A; BAZ2A; BAZ2B; TFCP2; FOXO1; TEAD1; RFX7; ZBTB38; MKL2; ATF5; NR1I2; RUNX1; ANKRD1; AHR; MEIS1; MITF; KLF9; KLF6; SFPQ; DNAJC1; RUVBL2; YEATS4; POLR2A; NCOA3; HDAC9; TP53; EMX2; CHD3; TOPORS; ZNF226; SIAH2; SCAND1; HOXA11; PIAS3; RYBP; NR1D2; IKBKAP; HSF2; RBPMS; MYRF; BAZ1A; HDAC4; CARM1; NRBF2; BIRC2; KLF10; STAT1; TBL1X; NAB1; HOXA10; EHF; KLF2; LMCD1; MED1; EYA2; NEDD8; TCFL5; ELK3; KDM5D; PDLIM1; HLF; ZKSCAN1; FOXJ3; MAFB; TXNIP; CREB1; FLNA