Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76721	Vx-745	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	SOX2; DMTF1; ZNF273; TULP3; SMAD3; FOXA1; ST18; FOXG1; JUP; MYRF; HOXD11; CRYM; SOX15; PIAS4; NFATC4; TERF1; SOX13; TRPS1; EN1; FOXF2; ZNF74; FOXE1; HDAC9; TFAP2C; NR2F1; SALL1; LIN28A; VGLL1; IRF9; SSX1; SPDEF; PDLIM1; TCF21; THAP7; AR; ATF3; PFDN5; ARNT2; FOXF1; BARX1; LOXL2; HOXB2; HHEX; VPS72; E2F8; KAT2A; TOX3; ZNF232; NANOG; ZBED2; PLAG1; SUPT3H; SMARCA1; DDIT3; MYBL1; NKX2-2; WT1; HIRA; BCL11A; SNAI2; PBX1; MYCL; PEG3; KLF5; ELF3; STAT1; TSC22D1; ZEB1; IRF6; CITED2; ZNF91; ERBB4; TGIF1; TBX3; JUN; ZFPM2; MEIS2
Down-regulation	156	ARID4B; NPAT; TSC22D2; TRIM32; KDM5A; ZBTB43; CTR9; CAPN15; TTF1; EP400; NSD1; ZBTB11; CHD1; MAFB; NFIB; ZBTB18; TAF10; ZNF587; SF1; RBM14; DDX5; HMG20A; EGR3; ZBTB24; NCOR2; PATZ1; HNRNPD; BCL10; SOX4; REPIN1; TADA3; HMBOX1; CHD7; ZBED4; BCOR; PPARG; ZNF134; ZBTB1; ZNF672; STAT6; WHSC1; TLE1; NFKB1; EGR1; HOXC6; CTBP1; CBX3; ZNF84; NUP62; NCOA4; TFCP2L1; POLR2A; JARID2; GATAD2A; EWSR1; FOSB; BAZ1A; SMARCC1; NKX3-1; KLF7; MXD4; KAT7; KDM2A; REST; KLF11; E2F3; ZZZ3; BATF; ZNF189; CCDC59; RNF4; ARID4A; ATF7IP; KMT2A; ATF1; SMAD2; PURA; NFKBIA; NR1I2; ZNF551; ZNF629; TRIM28; BRPF1; ZBTB20; XBP1; CDK9; HIVEP1; TRIP6; MSX1; VEZF1; SIAH2; NFATC1; ZNF274; CENPB; MAGED1; IRX5; NRBF2; MTDH; ORC2; CHD3; KAT6A; NR2F2; SMAD7; NCOA1; PCGF2; CRY1; BCL11B; NRIP1; HEY1; ELK3; KLF2; HOXC10; SFPQ; SMAD1; JUNB; ELF1; KLF10; ATF4; NFATC3; HOXA10; TP53; NR4A1; HTATIP2; BRD3; HOXA5; BCL3; ENO1; BCLAF1; RFX5; ZNF589; HLTF; RREB1; HMGN3; RFX7; DACH1; FOXJ3; ZNF652; SERTAD2; VGLL4; NR1D2; ATF5; SPEN; BIRC2; BASP1; FOSL2; FOXC1; HOXB7; NR1H2; ZMYM2; RUNX3; TCFL5; DAXX; ERBB2; FLNA; KAT6B; LEF1