Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76720	Vx-745	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	59	FOXG1; MNDA; CRYM; TRPS1; NFIX; TUB; TAF5L; SUMO1; PAWR; PFDN5; BCL11A; TCF7L1; ATF3; AR; PBX1; ZNF74; SOX2; NFATC4; ZNF467; SRCAP; KLF13; NR4A2; RFXANK; ARID1A; PRRX1; ACTL6B; ZNF239; NR2F1; ST18; CITED2; CREB3L2; ARID5B; SSBP2; ZNF274; HOXB13; MTA1; EMX2; JUN; RBFOX2; NFE2; NR4A1; CREB1; MYCL; E2F8; HIRA; HDAC9; CALR; IRF6; ZNF331; ZFP36L1; SSBP3; ZNF611; BNC2; TCF21; DLX5; WT1; ERBB4; ZFPM2; IRF9
Down-regulation	103	FOS; TSC22D2; ZNF468; PTRF; TTF1; KAT7; SMARCA4; ZBTB11; RUNX1; CRY1; NELFB; BMI1; BCOR; PURA; STAT4; TMF1; RNF6; CTNNB1; DNMT3B; HNRNPD; ELK3; ERG; MED7; LOXL2; PPARG; BCL10; TCERG1; SIX1; CHD1; NFKBIA; USP22; HTATIP2; KDM5A; FOXO3; SFMBT1; HSF2; SKI; CHD7; TRIM32; SMARCC1; KAT6A; HIPK3; CLOCK; GTF2IRD1; RBPMS; NUP62; ETS2; PRKDC; SMAD7; RFX5; BRPF1; SMARCE1; BRD8; ZNF587; ZNF84; DNAJC1; NRIP1; NKX3-1; PDLIM1; TLE4; NRBF2; RNF14; TLE1; SUV39H1; MSX1; ZNF267; ASH2L; MTDH; KLF2; YWHAB; TRIM28; IRX5; PBX3; XBP1; ZNF131; ZMYND8; MNT; NCOR2; CRK; ATF5; BHLHE41; SIAH2; SOX11; SMAD5; FOXJ3; MTF2; FOXD1; BIRC2; KDM5D; TCFL5; MED1; STAT3; ENO1; SATB1; VGLL4; BAZ1A; RUNX3; HLF; ERBB2; AHR; ZMYM2; ABL1; FOSL2