Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76691	Ruxolitinib	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	EYA1; FOXA1; EN1; USP21; SP1; HOXD1; MNDA; NR1H3; RNF138; RBFOX2; GFI1; E2F8; ARID5B; ZNF557; ZNF536; ZNF22; HDAC9; NKX2-1; PAWR; MED17; NFE2L3; ZNF345; CEBPA; RARB; IRF6; THAP10; CDK9; ZNF768; SSX1; GTF2F1; PSMC3; FLI1; ZNF12; CTBP2; KLF4; CBX4; ZNF74; HOXC10; ETS2; ZNF33B; POU4F1; TOX3; FUBP1; SREBF2; ST18; HOXB13; OLIG2; GTF2I; TCF7L2; SSRP1; FOXE1; CD3D; NEUROD1; HSF1; ANKRD1; CRYM; MYB; TFAP2C; YEATS2; INSM1; ARNT2; TBX3; NR2F1; FOXF1; ZNF573; PROX1; TTF2; CBFA2T3; NFKB2; HHEX; ZNF512B; FOXF2; SMARCC2; ILF2; PRDM2; HIRA; SNAI2; SOX11; TFAP2A; NR2F2; CERS6; HOXA10; TLE2; BCL11A; ZIC1; TGFB1I1; MYCL; ZBTB18; NPAS2; BASP1; ZNF43; TWIST1; CITED2; ZKSCAN1; ZNF117; DACH1; HEY1; ZNF423; ZFPM2; ATF5; HOXB6; ABL1; MYBL1; WT1; POU2AF1
Down-regulation	159	FOS; TSC22D2; LITAF; RBBP7; SOX15; SUPT4H1; UBE2B; CTNNB1; ETV1; EZH2; YWHAB; TFDP2; ZMYND8; PPP1R13L; STAT6; ZNF410; CTR9; NFIC; NUP62; ZNF222; PTRF; ZNF432; ZNF165; VEZF1; ZBTB11; ING3; HCFC2; CCNC; HIVEP2; CASZ1; TRIP6; MAFG; ZBTB7A; FOSB; CBX3; BANP; CCDC59; CARHSP1; SUV39H1; NFIL3; PLAGL1; KLF6; DNMT3B; JUND; RNF14; DDIT3; NFIB; HMBOX1; CARM1; NKX3-1; UBE2I; DNAJC1; PSIP1; PPARG; FOXO3; SUB1; GLI3; CRY1; NCOA4; ELF4; ZBTB38; MAFF; CNOT2; SIN3B; RBPMS; HTATIP2; COPS5; PDLIM1; BRPF1; JARID2; RYBP; ASH2L; TBP; TAF10; KDM5A; MED6; ADRB2; WWTR1; JUNB; ZNF143; LPIN2; BRD8; CSDE1; CHD1; NRBF2; TBL1X; BBX; ORC2; ATF6; TCEA1; CCNA2; ZBTB20; BIRC2; NRIP1; FOXO1; TP63; ZNF587; KLF11; PRKDC; TRIM28; MTA1; DAXX; ZNF23; CBFB; ZBTB1; TOB1; BATF; PREB; SIX1; CRK; MSX1; XBP1; PIAS3; NR1H2; STAT1; C1D; PIR; PITX1; MNAT1; KLF2; HSF2; TCFL5; ATF3; ECD; FOXD1; TP53; KDM5D; SMAD5; ERBB2; ZNF131; TGIF1; EMX2; CREM; CUX1; CCNE1; BCL3; CITED1; MITF; ELF1; ELK3; TEAD1; YAF2; PEG3; STAT3; PTTG1; SIAH2; ZNF226; EYA2; PEX2; SCAND1; HLF; FOSL2; FOXJ3; HOXA5; CREG1; KAT6B; NR1D2; ATF1; FLNA