Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76679	Pf-477736	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	269	IKZF1; ZNF586; TRPS1; ID2; HOXD3; GATA2; EN1; MNDA; TCF7; GATA6; NFKB2; RARG; SOX18; HOXD1; PRRX1; PRRX2; FOXF2; SOHLH2; DMTF1; SMAD6; SMARCA1; ZNF682; ID4; ZNF93; ZNF623; ZNF415; PCGF3; ZNF671; ZNF711; VGLL1; PAWR; ZMIZ1; SOX10; ZNF701; E2F2; CEBPG; CREM; HOXC13; THAP10; KLF9; TFAP2C; HESX1; ZNF506; BCL11A; ZNF571; ZFP2; NEUROD6; SPDEF; ZNF273; CREBL2; NAB2; TOX; RBPJ; ZNF117; HDAC11; ZNF329; ETV6; SMAD3; YAP1; ZXDC; ZNF536; TFEC; HDAC9; TULP4; ZFPM2; CEBPA; CTBP2; ZNF160; ZNF253; BHLHE41; NR2F1; NHLH1; EPAS1; ZNF33B; ZSCAN32; ZNF257; ZFP37; ZNF721; ZNF492; KLF3; ZNF248; ZNF141; ZKSCAN3; IRF6; TXNIP; TP73; DAXX; PAX2; MXD3; ZNF816; ZNF14; PAX6; HIRA; ZNF124; POU4F1; DLX5; ZNF345; ZNF112; EMX1; NKX2-2; SNAI1; NAB1; CAMTA1; PNRC1; CREB3L2; CBFA2T2; ZNF580; BBX; ZNF148; SOX17; GBX2; ZNF175; ZNF43; MED7; RBL2; ERBB4; TERF1; NR4A3; ZNF665; TAF5L; HOXB6; MYCN; WT1; ST18; TOX4; ZNF529; ZNF444; CARHSP1; VENTX; SP110; DLX4; NEUROD1; ZBTB44; WWTR1; ZNF264; ZNF606; TDRD3; ZNF331; ZNF544; GTF2I; TFAP2B; NCOA2; ING4; ELF3; HOXD13; PEX14; FOXG1; NPM1; FOXF1; EYA2; SOX2; NFIL3; RBL1; ZBTB38; IRF9; LIMD1; ZNF239; DDIT3; SOX11; ZNF611; BARX2; IRF7; THAP7; PRMT2; LOXL2; FOXE1; TRIM32; TCF7L2; PHF20; TRIM24; TBX3; MYRF; GCFC2; ZNF91; ZNF354A; ZNF135; DNMT3B; TOX3; ZNF74; ZFP36L2; CDIP1; ACTL6B; ESR1; NR0B1; ZNF85; TGIF2; CERS4; SALL1; NANOG; ZNF195; CBX4; ZNF350; PAX5; ZNF573; LIN28A; JUNB; MAML1; WWP1; HOXB2; BCL3; NFE2L2; PLAG1; ZNF184; HHEX; RERE; MYCL; EHF; TRIM22; IL16; ZBTB1; URI1; ZIC1; CNOT6; KAT2B; ZEB1; ZBED1; BANP; CREB1; VGLL4; ZBTB20; SAP30; NR2F6; MTA1; PHIP; RAD21; NFE2L3; PRDM2; TCF4; KLF10; BACH1; ING2; ZMYND8; CBFA2T3; TAF9B; MYBL1; CXXC1; HEY2; FOXC1; HOXB13; SATB1; ATF5; MAF; JUP; ZNF302; ZNF430; ZNF467; ATF4; MXI1; ZNF131; HMGN3; AR; VDR; ELF5; TFAP2A; ITGB3BP; OSR2; SOX9; IRF4; KAT6B; DLX2; NR4A2; LMCD1; SERTAD2; MEIS2; BTG1; NR1D2; ZNF423; HIC2; PEG3
Down-regulation	341	SUZ12; PSMD9; CTR9; FOS; PRKDC; ZBTB7A; HDAC6; NELFB; ARID4B; ESRRA; ZBED4; HIPK1; IKBKAP; EZH2; TCF3; TTF1; TSC22D2; ELK1; TRIP6; NFIC; SAFB2; MAZ; ADNP2; UBE3A; HDAC2; LDB1; HMGB3; HES1; YBX3; CIC; MLXIPL; CAPN15; TRAF6; PHF8; ETV1; BAZ1A; ERCC2; CSDE1; TAF4; HTATIP2; ZBTB43; ZNF384; PLAGL2; STAT6; NFKBIA; JARID2; BRF2; RHOA; RBBP5; TRIM33; FOSL1; MLX; EP400; PCGF2; TCERG1; CRY1; TAF10; PPP1R13L; CCNA2; SUPT6H; TSG101; REXO4; KAT2A; GTF2A1; ZBTB24; MED20; BRCA1; RELA; WDR77; CCNC; SUB1; SP2; RORA; CIZ1; WHSC1; SETDB1; GTF2IRD1; TBP; ZNF783; RNF10; HIVEP2; PHF2; KMT5A; SMARCC1; XRCC6; TFAM; UBE2B; CCDC59; SF1; SIX2; MLLT10; BMI1; UBTF; SETD3; SUPT5H; SNIP1; BTF3; BAZ1B; EED; ETS2; HDAC1; ZNF408; YY1; HMG20A; POLR3F; ORC2; BLM; FOXO3; KDM5B; THRAP3; SP1; HSF2; SMARCA4; RUNX1; TFE3; BRD8; GATAD2A; RCOR3; ZNF281; RCOR1; TAL1; ZNF672; E2F3; CASZ1; USP22; ZNF274; TFCP2L1; KAT5; FOSB; ADRB2; PPRC1; KMT2B; CEBPZ; PPARG; C1D; MTF2; MED1; NR2F2; ZBTB48; TAF11; ZNF32; RUVBL2; MTF1; ZHX3; DDX54; NCOR2; ZNF646; RBBP7; RBM14; PCGF1; EGR1; UIMC1; CHD9; TSC22D3; EWSR1; NUP62; TP53; ZNF410; TRRAP; CDK8; KAT8; HIPK3; SETD2; ACTL6A; CEBPD; ZNF576; NRF1; NR1H2; PRDM4; PATZ1; MED13; ZFHX4; RBBP4; MED24; CBX3; CHD1; SREBF1; E2F6; THAP11; MED15; CTBP1; DDX5; ZNF107; TLE1; CALR; NRIP1; CDK9; ELF2; GATA3; RRN3; MEF2D; GABPB1; ARNT; ISL1; PLAGL1; SFMBT1; ID3; MECOM; HEY1; SIX1; MYCBP; TGFB1; SLC2A4RG; CRK; ZNF143; FLI1; ATF1; HOXA11; KDM2A; HOXA10; KLF11; SOX13; ZNF692; PITX1; NR2E1; ZMYND11; PBX2; SOX15; SIN3B; CENPB; TLE4; NKX3-1; MBD2; PA2G4; RSF1; SUV39H1; SPEN; SIM2; WDHD1; ASH2L; MAFG; ZNF45; BAZ2B; MKL1; SREBF2; RFX7; POLR2A; HOXA7; PTRF; MITF; MTDH; ARID1A; LITAF; CCNE1; USF2; HMGB1; REST; TMF1; PAXBP1; ZFHX3; SSRP1; ERBB2; BTAF1; TCF12; SUPT3H; MED23; AATF; CHD7; DPF2; NR3C1; UBP1; PMF1; ZNF426; TOPORS; BACH2; MED14; ECD; PREB; BCOR; ZBTB11; CRYM; ZNF267; NFX1; STAT1; TCF15; CNOT2; HIVEP1; FUBP1; ZNF516; SIAH2; PBX3; KDM5D; AFF1; HOXA4; FOXO4; MNAT1; MAGED1; ELK3; BRPF1; YBX1; TSC22D4; KAT6A; NEDD8; IKZF5; GLI3; BRD4; AGO2; ZNF84; PSMC3; FOXN3; NCOA3; CREBZF; PPARGC1A; HOXA5; MED17; EGR3; BRIP1; VEZF1; YWHAB; LPIN2; FOXJ3; NR1I2; ERG; MED6; NCOA4; ZNF629; MGA; ZFP36L1; RNF6; TTF2; TCF21; KLF4; DEK; HOXC6; FOXD1; RYBP; TBL1XR1; NRBF2; HLTF; YAF2; CBFB; MLXIP; ELF1; SALL2; BATF3; MEIS1; CREG1; PBX1; NFATC3; ZBTB16; FOXO1