Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76665	Ibrutinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	TRPS1; TEAD4; TRIM29; LOXL2; TP63; RFX5; DBP; ZNF468; ZNF146; ZEB2; SIX2; DDX5; TSC22D3; NFE2L2; YBX1; RERE; MBD2; SAP30; ZFHX4; SMARCA2; KLF5; NPAS2; NFE2L1; HMGB2; KAT7; MITF; TCEA1; MTDH; SMARCD3; ELK3; XBP1; HDAC4; HSF2; PRKDC; HOXA5; SMAD2; EDF1; EGR3; SCAND1; DAXX; ARID5B; HOXB2; ATF5; ELF1; PSIP1; MEIS1; MED1; NR1H2; TOB1; PITX1; FOSL2; BASP1
Down-regulation	59	CCNT1; NR2F6; FOS; ARL2BP; CDX2; POU2F1; PBX1; TAF4; NKX2-1; ZHX2; CERS6; REL; ARID1A; ZNF22; NR2C1; PFDN5; ETS1; CHD9; TCF7; NFAT5; PBX2; CBFA2T3; KLF9; POU2AF1; CRYM; SUPT3H; LMCD1; BAZ2B; E2F8; JARID2; NR0B1; HIC2; ZNF117; ZNF652; ZBTB16; CREB3L2; PAX5; ERBB4; LEF1; HIRA; TBX3; ZEB1; ZNF423; JUN; MYCL; CREG1; SATB1; CREB1; NRIP1; ZFP36L1; MYBL1; AEBP1; TOX3; MSX1; ABL1; KAT6B; ZSCAN18; TCFL5; ZFPM2