Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76664	Ibrutinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	TRPS1; SIM2; GRHL2; EYA1; NFKB2; CEBPA; CTBP2; SOHLH2; RORA; URI1; USP21; TEAD3; ZSCAN31; ZNF536; ID2; WWC1; HOXC6; CAMTA1; NPM1; HOXC10; MNDA; CD3D; CBX5; TSC22D3; RFX5; HOXC4; ZNF467; FOXF1; BHLHE41; TCF7; POU4F1; NHLH2; IKBKAP; ENO1; PAX6; EYA2; MYCN; PIAS3; NFATC3; FOXF2; FOXC1; TLE4; YEATS2; PHIP; MTF2; CERS6; SMARCD3; HMGN3; LEF1; DLX5; TRIM22; SPEN; DNAJC1; TBL1X; JUP; PHF20; ZNF131; MLXIP; KAT2B; CREG1; TBX3; TOX3; TP53; TRIM16; HOXA10; MYBL1; GTF3A; IRX5; IRF6; TRIM29; NR2F2; ZBTB38; BACH2; STAT1; OSR2; SATB1; PSIP1; ERBB2; KDM5D
Down-regulation	85	FOS; FOSL1; CDYL; MYCBP; EGR4; TRAF6; HDAC6; VPS72; SOX4; TAF1A; HLX; RUNX1; ZNF281; MAFF; TTF2; HMGA1; BCL10; FOXG1; NLK; TSC22D2; NR1I2; ENY2; MEF2A; MECP2; MED7; ELF4; JUND; KLF5; TCF7L1; RYBP; TBPL1; MED13; HDAC9; MED27; NR1H3; HMGA2; THAP1; ID3; E2F3; ACTL6A; SMAD3; ZNF91; TFCP2L1; BRD4; LPIN2; KLF10; OLIG2; ZNF267; C1D; MKL2; NFATC4; ASH2L; ZNF143; JUNB; NR1H2; CDK9; TMF1; USP22; ID1; MNAT1; HHEX; NFE2; CRYM; ZNF432; BRIP1; STAT3; KLF7; BBX; TWIST1; ABL1; PDLIM1; NEDD8; ATF5; TSC22D1; HEY1; MEOX1; NR4A1; CREB1; ZKSCAN1; SNAI2; ATF1; PEG3; PITX1; SCAND1; TCFL5