Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76662	Ibrutinib	GSE92742	MCF10A	Human	6h	10uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	95	ZXDC; KDM4A; TEAD3; TCF25; CEBPA; TSC22D3; TRPS1; NFKB2; TCF7; USP16; MBD1; ELF5; TFDP2; RREB1; TCF7L2; TFAP2C; CEBPD; WNT4; NFIL3; MBD2; HMGB2; HOXB13; CENPF; PITX2; CNOT1; HSF1; GRHL2; CBX4; STAT4; NR5A2; ZNF189; FOXE1; NFE2L1; SIN3B; ZNF468; BCL6; THAP10; MXI1; SP140L; TSC22D1; RCOR3; ENO1; SREBF1; NR4A2; ZNF721; MNDA; NFE2L2; ZNF12; FUBP1; PDLIM1; BCL11A; SIAH2; ZNF33B; EDF1; CREB3L2; POU4F1; DAXX; KLF9; NR2F1; HMGN3; BBX; PHIP; HIRA; RFX5; ZNF331; ZFPM2; PQBP1; RAD21; RNF10; ATF7IP; TP53; KLF6; OSR2; MAF; HOXC6; ZNF160; SATB1; MEIS2; ZNF611; PBX3; IRF8; MAFB; HOXA5; RUNX3; NFE2L3; TLE2; IRX5; ZNF43; ERBB4; ZNF512B; ZNF131; SPEN; MYBL1; TOX3; WT1
Down-regulation	144	FOS; FOSL1; C1QBP; LOXL2; MYC; TSC22D2; VPS72; TRAF6; RERE; RBBP5; FOXA2; WDR77; CTR9; SIRT7; ETV1; TCF12; MAFG; SAFB; NR0B1; TFEC; EGR3; YBX2; SMAD1; FLI1; MTF1; EGR1; LITAF; SOX4; POU5F1B; ZBTB7A; ZNF692; HIPK3; ZNF177; SMARCD1; E2F5; PBX1; CBX6; FHL2; RBPMS; ZNF410; HIVEP2; RRN3; HIF1A; PHF8; ZNF165; TAF10; SOX15; JARID2; ZNF24; PPRC1; MKL2; EED; HES1; ISL1; E2F6; TSG101; ADRB2; SAFB2; SSBP2; ZFP36L1; TULP4; CCNH; CHD7; E2F3; PTRF; NFIC; MLXIP; ELK3; ZNF143; ERG; PATZ1; TLE1; SOX17; DNMT3B; MECOM; RBM14; PSIP1; MSX1; ZBTB18; ASH2L; ST18; NUP62; SALL2; MEOX1; BACH2; TAF1; TLE4; NFATC4; MAFF; BAZ1B; JUNB; ESR1; IRF1; TOX; STAT6; RBBP4; POU3F2; HHEX; MYRF; HOXA10; TRIP6; ZBTB1; SMAD7; PRKDC; NFE2; HDAC4; HMGB3; JUP; ZEB2; CUX1; TBL1XR1; ID4; RYBP; SMARCA1; HIC2; TCEA1; CREB5; ATF5; SMARCD3; MITF; USP22; PRRX1; YWHAB; ZBED2; ZNF91; KLF10; IRF9; CRK; IRF4; ID3; FOXO1; GABPB1; ZSCAN18; MNAT1; ASCL1; KAT6B; ZFP36L2; TCF4; VDR; ZKSCAN1; INSM1; MED1; PEG3; TCFL5