Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76661	Linsitinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	HES1; CRYM; HIF3A; GATA6; MEIS2; FOXG1; HDAC9; TRPS1; THAP10; TCF7L2; TULP3; ERBB4; PAWR; NR5A2; ID4; PRDM2; ZNF623; ZSCAN9; HSF4; ZNF85; ZBTB17; ZNF107; ZNF44; E4F1; AR; BCL11A; RFXANK; ZNF415; RING1; EMX2; MZF1; TSC22D3; ST18; TCF7L1; SUPT3H; VGLL1; ING4; CBFA2T3; ZNF34; PSMC3; ZNF195; SNAI2; IRF9; ZNF816; CITED2; DLX2; ZNF217; SOX2; ZNF253; MYCL; SUMO1; ZNF467; HLX; NEUROD1; POLR3C; OVOL2; GRHL2; INSR; IRF7; THRA; MEIS1; PHOX2B; PLAGL1; ZSCAN31; ZNF93; SPIB; ZNF239; PAX6; FUBP1; PRRX1; MNDA; ATF3; CREB3L1; ZNF721; ZNF91; PFDN5; ARNT2; ZNF611; OSR2; E2F8; ACTL6B; TLE2; ZNF432; HIPK2; ZNF430; ZFPM2; TCF21; HOXB2; MECOM; ZEB1; ZNF160; DACH1; RBBP8; ZNF43; TTF2; KLF5; ZNF665; ZBTB16; ZIC1; PNRC1; MYB; NFE2L3; TOX3; INSM1; NKX2-1; KLF6; PQBP1; HIRA; NR4A1; TFAP2C; SMARCA1; HOXB6; NR2F1; EYA2; RBPMS; VPS72; ZNF264; EHF; ZNF423; ZNF117; RAD21; JUN; TOX; ESR1; ISL1; SOX17; PEG3; PBX1; IRF8; TXNIP; TOB1; NR4A2; CREB1; TCF4; ZKSCAN1; ARID5B; ASCL1; ZSCAN18; ID3
Down-regulation	186	PARP1; HMG20B; FOSL1; TSC22D2; IKBKAP; GTF2IRD1; PPRC1; ELK3; NKX3-1; RBM14; CTR9; UBE2I; NELFB; ZNF672; CENPF; NPAT; DNMT3B; NUP62; BCL11B; SOX15; DRAP1; TTF1; TRIM16; CRK; E2F3; PML; TRIM32; ADRB2; THAP11; ZBTB38; MYC; ZNF281; BLM; SUV39H1; TRIP6; CBX6; GATAD2A; ZBTB7A; JARID2; TAF10; SETD2; SFPQ; ID2; HDGF; ZBED4; TRIM27; CEBPZ; NRIP1; AFF1; BCOR; RNF141; MLX; BBX; HNRNPD; BRD3; BRPF1; MTA2; WWC1; TADA3; CHD1; RNF10; RBBP4; CARM1; KDM5A; ZEB2; STAT4; POLR2A; TCERG1; NFKBIA; HLTF; MTF2; SMAD2; ZNF184; PPARG; RNF14; RHOA; MED1; MAGED1; TBP; RUNX3; KDM2A; HOXC6; LPIN2; HIPK3; MNT; CRY1; DDX54; MAFG; BCL3; ZNF23; RNF4; BMI1; KAT6A; DR1; SFMBT1; ZNF532; ZNF131; MTA1; NFATC1; RFX7; PREB; AGO2; HOXA5; PBRM1; BCL10; ALX1; CTNNB1; XBP1; RXRA; TAL1; HOXC10; USP22; PRKDC; SMAD3; ORC2; HDAC1; NFKB1; BASP1; PIR; BRD8; CBFB; JUNB; ASH2L; MAX; PDLIM1; BIRC2; PIAS2; TRIM28; URI1; SMARCA4; RUNX1; CARHSP1; SMARCE1; USF2; BCLAF1; SMAD5; HTATIP2; TRIM29; SMAD7; CBX3; ETS2; DNAJC1; WHSC1; CHD7; TRRAP; SAP30; PCGF2; HSF2; FOXJ3; TMF1; SMARCA5; TEAD1; MED24; CBX5; NRBF2; SREBF1; NR0B1; PITX1; RFX5; TFAP2A; TP53; ABL1; FHL2; ZMYM2; HMGN3; FOXO1; NCOA6; MAFF; NR2F2; PHF20; ING2; SIX1; ERBB2; GTF3A; SMARCA2; NR1D2; TBL1X; FOSL2; BACH2; IRX5; STAT1; SCAND1; LEF1; MLXIP; KDM5D; FLNA