Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76660	Linsitinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	TRPS1; TCF25; EN1; GRHL2; REL; ZMIZ1; TEAD3; TULP3; ZXDC; ZIC1; SP140L; NEUROD1; ZNF345; SMARCA1; GLI1; CDX2; BCL11A; SMAD3; PRRX1; CEBPA; NFKB2; DLX4; NFE2L3; ELF5; TCF7L1; NHLH1; RAD21; PITX2; ZSCAN31; ZNF292; IRF8; ZNF623; NKX2-1; DACH1; CBFA2T3; ZFPM2; TOX4; TSC22D3; TBX5; NONO; RORA; ZEB1; CBX4; TCF7; ZNF195; PPP1R13L; CHD9; ACTL6B; HDAC9; SP100; TFAP2A; GTF2F1; NHLH2; TDP2; ZSCAN9; SRCAP; ZNF12; IRF6; ZNF148; TOX3; INSM1; GATA6; HIRA; CDK8; ZBTB16; SLC2A4RG; TLE2; PNRC1; FOXE1; ID4; CREB1; DEK; ESR1; DLX5; MAF; ZNF33B; IRF7; PRDM2; PBXIP1; TFAP2C; MYBL1; ZNF22; TXNIP; ZNF430; ZNF117; PFDN5; TBX3; HOXA10; NR0B1; ZBTB20; BTG1; POU4F1; MYB; TCEA2; ZHX2; PHIP; ZNF160; IRF9; EHF; FOXF1; MYCL; MEIS2; ATF5; JUN; BASP1; ZBED2; CITED2; ERBB4; IRX5; ERBB2; ZFP36L1; TRIM22; ARID5B; OSR2; ASCL1; BHLHE41; POU2AF1; TCF4
Down-regulation	166	FOS; CBX6; MYCBP; MTF1; ZBTB24; SIX2; SOX15; SMARCD1; CTNNB1; NUP62; NFYB; FOSL1; NELFB; NKX3-1; SMARCA4; ZNF672; TSC22D2; TLE1; UBE2I; ZNF432; ADNP2; HCFC1; TAF1D; BCL10; TMF1; NFX1; BRCA1; NFIC; CALR; PA2G4; HCFC2; NPAS2; RBM14; EMX2; RUVBL2; ZSCAN5A; TCERG1; SETD2; TRRAP; LHX1; DPF2; EWSR1; BTAF1; HES1; ZBTB7A; TAF10; SUB1; TBP; JUNB; LITAF; UIMC1; TSC22D1; NFKBIB; MTF2; SUV39H1; SFMBT1; ETV5; SMAD5; SNIP1; AGO2; ZNF552; ADRB2; SMARCA2; HIPK1; TOPORS; ADNP; TFAM; BATF3; RUNX1; IRF2; PMS1; BAZ1A; EGR1; HNRNPD; ZFP64; PIAS3; ZBTB18; KDM5B; CCDC59; HSF2; MAFG; RFX5; NR1H2; ISL1; TBPL1; SFPQ; PDLIM1; PHF8; LEF1; TOB1; PITX1; CRK; ZNF281; CHD1; CRY1; PIAS2; RNF10; RNF141; KDM2A; BRPF1; YBX3; PRKDC; PPARG; TSC22D4; HMGA2; ELK3; ORC2; TBL1XR1; CBX3; AIP; GATAD2A; KMT2A; PHF2; IL16; TP53; HDGF; ZBTB11; PSIP1; ZNF532; YAF2; ATF1; SMARCE1; MYRF; RBL2; PREB; TRIP6; RFX7; MEIS1; HEY1; AATF; KDM5D; TP63; JARID2; BAZ2A; YWHAB; ZNF143; MED1; SAP30; DNAJC1; AES; GABPB1; MXD1; RYBP; AFF1; BMI1; HOXC6; CHD7; CARM1; XBP1; TLE4; NFIB; HOXA5; MNT; HDAC4; TCFL5; NR4A1; RUNX3; HOXC10; FOXJ3; FOXO1; KLF2; CCNH; WT1; TRIM29; DAXX; FOSL2