Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76659	Linsitinib	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	TRPS1; SSBP2; FOXG1; CRYM; TCF7L1; HIF3A; ZMIZ1; ZNF623; TCF7; TERF1; NAB2; TSC22D3; SUPT3H; ST18; EN1; KLF9; IRF6; SALL1; HDAC9; PNRC1; TBX21; TCF25; ERBB4; ZNF423; NEUROD2; HIRA; NEUROD1; BCL11A; EYA1; IRF9; ZNF721; HOXD1; HDAC5; HSF1; MECOM; HBP1; DLX4; ZNF239; TP63; RING1; ESR1; HOXD11; PAX6; PEX14; ZNF611; NCOA2; TAF5L; PBX1; ZSCAN31; MYCL; CBFA2T2; KLF13; E2F8; EZH1; BCL6; KLF1; PAX5; IRF7; STAT1; LIN28A; JUP; MAF; MEIS2; GATA6; TOX; NKX2-1; ZIC3; PIAS1; NFE2; FUBP1; ZNF160; THRA; ID4; NR2F1; PRMT2; ZNF544; IRF1; IRF8; VGLL1; KAT2B; SPDEF; MAFB; RAD21; NR0B2; CBX7; TFAP2C; ZHX2; TOX3; PHIP; ZNF91; ZNF573; ZFPM2; PRRX1; VGLL4; PFDN5; FOXN3; ZBTB16; SMARCA1; OSR2; HLF; CALCOCO1; NR1H4; TCEA2; FOXF1; SOX2; CD3D; TLE2; ZNF33B; JUN; NFE2L2; ZNF665; ZNF264; ARID5B; ZNF467; ZNF93; ZIC1; CREBL2; TRIM22; POU2AF1; MYBL1; KLF5; ZEB1; HOXB13; ZFP36L1; BACH2; NFKB2; SSBP3; DLX5; SOX17; ZNF512B; DACH1; CREB1; ATF3; INSM1; DLX2; HOXB2; HOXA5
Down-regulation	199	FOSL1; FOS; RUNX1; ELK3; E2F3; NELFB; CCNA2; ZBED4; ZNF146; LITAF; CEBPZ; UBE2I; TSC22D2; TTF1; SOX4; CTR9; ELK1; RBBP4; IKBKAP; NUP62; GFI1; MLLT10; CRK; SUPT4H1; DRAP1; FOSB; SMARCA5; ADRB2; BAZ1B; RNF6; MYC; ETS2; GABPA; ZEB2; SIM2; GTF2IRD1; PPRC1; RBM14; TFAM; BCL10; CHD1; RHOA; UBE2B; MTF1; TBP; GATA4; ARL2BP; YWHAB; SSRP1; NFYB; PURA; PPARG; UIMC1; ZNF764; RNF14; NKX3-1; POLR2A; HIPK3; HCFC1; TSC22D4; MAGED1; CRY1; RNF141; ZNF23; MTF2; NFKB1; BAZ1A; FHL2; AFF4; SNIP1; TRIM28; CENPB; GATAD2A; BRD8; SMAD5; VEZF1; HSBP1; TAF10; MED1; SUV39H1; XBP1; HTATIP2; BMI1; ZFP64; THAP11; PIAS2; ZNF672; TCERG1; NRBF2; MED7; KDM5D; KLF6; ZNF337; EZH2; ZMYND11; HES1; TMF1; TRIM32; TAF9B; EED; ZBTB18; MED6; RFX7; TFAP2A; PTRF; HDAC1; DPF2; ADNP; HSF2; HNRNPD; EGR1; HMG20A; DDX54; NCOA4; SFPQ; USF2; CALR; ZBTB38; PATZ1; PDLIM1; CBX3; HMGB1; RRN3; JUNB; HLTF; BCOR; URI1; ZNF426; CTNNB1; MITF; TEAD1; REST; TLE4; TRRAP; CHD7; YAF2; ORC2; VDR; ING2; ATF1; MAFG; TRIP6; ECD; HMGA1; ZNF629; SIX1; WHSC1; MXD1; HOXC6; AATF; TGIF1; HMGA2; SPEN; BASP1; ZMYM2; BRPF1; BIRC2; CREB3L1; RUVBL2; ENO1; EGR3; AFF1; MSX1; CBFB; SAP30; FOSL2; NPAS2; PREB; SATB1; MNAT1; ZNF165; ELF1; CARM1; CHD3; SMARCA2; FOXD1; MEOX1; SIAH2; FOXO1; TFCP2; TRIM16; ATF4; HOXA10; PBX3; TP53; DAXX; TOPORS; MLXIP; RUNX3; IRX5; TSC22D1; MYCBP; ERG; TCFL5; ERBB2; AEBP1; FOXC1; NR1D2; SOX9