Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76658	Mk-1775	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	345	FOXG1; IKZF1; GATA3; ID2; SOHLH2; LHX2; KDM4A; HDAC6; ZMIZ1; DMTF1; PPARG; TFDP2; BCL6; MKL2; NFKB2; HAND1; TCF7; NR5A2; TFEC; TRPS1; ZNF219; KLF4; PHF1; ZNF552; NR4A2; STAT4; CNBP; DNMT3B; TRIM24; SAP130; ZNF835; BRCA1; FOXA2; ZXDC; SALL1; HOXC5; CBX6; ZEB2; MNDA; FOXJ1; PRRX1; KDM5C; CDX2; HESX1; CHD2; LHX3; SATB2; TP63; LIN28A; CREM; RARG; POU4F2; ZNF580; CBX4; MLLT10; SSX7; IRF5; HNF1B; ZNF446; SSX1; ZNF444; SSX3; MYCN; HR; RFX2; ZNF506; RXRG; SOX21; EP300; PHOX2B; CIR1; ZFHX4; SHOX; RING1; FOXJ2; LDB1; HAND2; ZNF93; TGIF1; NEUROD6; ZNF682; TLX2; FOS; HOXC11; ZNF331; KLF3; KDM4C; ETV1; PRDM2; HOXD3; SOX5; POLR2A; SPDEF; MBD1; ZNF253; ZNF45; MAGED1; ZNF816; PRDM5; ETS2; ZNF711; ZBTB7B; NAB2; ZNF492; ZNF671; BATF; SOX10; CBX2; GCM1; PRDM14; MAF; IL16; PAWR; SOX3; SP140; FOXJ3; NCOA1; IRX5; TOX4; CNOT2; VHL; ZNF329; ARID3A; YBX1; LZTS1; POU3F1; HMGN3; ZNF695; TOX; ZNF528; ZNF701; HOXD1; SOX2; SP4; FOXF1; BHLHE41; TCF4; ZNF202; GATA6; CAMTA2; ZKSCAN4; NR2F1; SNAI1; ZIC3; ZNF257; RFX3; RXRA; GATA1; RNF2; TCF7L1; CTBP2; NKX2-2; ERBB4; PAX4; SOX30; TCF7L2; ZNF571; TSC22D1; POU2F3; ZNF254; MNX1; TFAP2B; CAPN15; ZMYND8; ATN1; CDX1; TDP2; NANOG; ESRRB; PBX2; HEY2; ZFP36L2; ZNF75D; SOX11; EYA2; ZNF107; GTF3A; RBM39; MAPK8IP1; MTF2; RORA; JUNB; BRDT; CREB1; ZNF467; TULP4; ZBTB25; ZNF623; BNC1; EPAS1; CAMTA1; DAXX; NEUROD1; TRIM27; ZNF35; CREB5; BCL11B; HSF4; LIMD1; ZBTB17; ZBTB48; ZNF263; VGLL1; PKNOX1; TP73; MYOG; KLF5; BLM; PBX1; JUP; NR3C2; IRF4; ZNF85; ZNF589; STAT1; ZIC1; MYF6; SATB1; PHIP; TRIM32; JAK2; DLX2; PIAS3; NFATC1; TAF4B; PFDN5; PMS1; ING1; ZNF131; MEOX2; TLE4; NHLH1; KDM2A; BCL11A; PARP1; PAX9; ZNF200; NFKB1; CCNT1; MEIS1; TAF1C; ZNF134; MDM2; BCL10; AFF4; LYL1; MED12; PPARD; SUPT7L; HIVEP1; THAP10; ZNF91; MYNN; HEY1; ZZZ3; ZBTB40; CERS4; TDRD3; PGR; IRF3; ERBB2; ESR1; HMBOX1; OVOL2; NR4A3; BACH1; E2F2; RARA; CREBL2; MSC; SP140L; IRF9; SUPT3H; ZNF415; DNAJC1; THAP11; CDK8; PKNOX2; PRDM1; PDLIM1; ZNF141; MYCL; CHD1; ZNF423; ZNF304; ZNF268; BAZ2B; ZSCAN18; SNIP1; TCFL5; FUBP1; NFIL3; LHX6; E2F6; ESRRG; SNAPC4; PBXIP1; CEBPA; ZNF43; ZFPM2; CXXC1; WNT4; DLX5; MDM4; ZNF721; LEF1; SMARCA1; HOXC4; CBFA2T3; ZMYM2; WWTR1; RNF6; UBP1; SSBP3; ZNF33B; AHR; FOSL2; MXD1; PROX1; FOXL2; HDAC4; REL; ATF4; PAX5; BASP1; ZNF117; NRIP1; KAT6B; ISL1; BHLHE40; MEIS2; WT1; SFPQ; EGR2; NR4A1; PREB; HIC2; HOXC6; ID4; HHEX; ELF1; SPEN; MYBL1; SOX17; PSIP1
Down-regulation	417	SUZ12; DRAP1; GTF2A2; RBBP5; FOSL1; ESRRA; IFI16; EZH2; TTF1; DNAJC2; SNW1; WWC1; MAZ; ZBED4; PRKDC; MBD2; COPS5; C1QBP; POLR3F; PTRF; RBBP4; RFC1; STAT6; MED6; PCGF1; GTF2IRD1; JUND; CBFB; MED17; HOXB3; TCF12; IKBKAP; TAF7; CRK; CTR9; NKX3-1; ABT1; ZNF212; TFAM; TSHZ2; HDAC9; TCERG1; YWHAB; ZNF3; SIRT7; TRIP6; UBE2B; ARID4B; MYBL2; ZNF146; PTTG1; NFKBIA; GTF2F1; CALR; WDR77; NPAS2; BAZ1B; NFYB; SND1; TSG101; ZKSCAN1; TULP3; RELA; MLX; PHF2; ZNF646; SP2; NFE2L1; SUPT5H; TGS1; L3MBTL1; ZNF668; FOXA1; ARL2BP; TBP; ZHX3; PPP1R13L; KAT6A; TFEB; MDFI; HDAC1; ZNF302; RUVBL2; NONO; CEBPZ; PMF1; LITAF; PCGF2; SMARCA4; TAF1D; MTDH; RNF14; SRCAP; ERCC2; CCNA2; KMT2B; SIX2; MLXIPL; ZBTB18; USP22; BRF2; KAT2A; COPS2; NFE2L2; TSC22D2; TTF2; ARNT; SMARCD2; MED23; ZNF274; SREBF1; CSDE1; ARHGAP35; ETV4; TBPL1; MAFF; NFIC; NELFB; HDAC2; MSL3; ZBED2; SETDB1; ZNF669; ZNF205; HIF3A; ATF6; ZNF426; NFIB; TAF4; HES1; RBPMS; HDAC7; SLC2A4RG; UBE2I; NCOA3; RRN3; HMGXB3; HIVEP2; CARHSP1; UBTF; RFXAP; GMNN; ZNF576; ASH2L; LOXL2; THRAP3; MEN1; KAT5; THAP1; ZNF135; KAT7; EMX2; ELK1; SMAD7; BAZ1A; SMAD3; TAF1A; ATF5; MYC; CBX3; HOXB7; EHMT1; MED13; ZNF337; DPF2; SSRP1; PHF8; ZNF544; TSC22D3; TERF1; FLI1; TERF2; MTA1; CENPB; AATF; ZNF32; SIRT2; RSF1; TFE3; SAP30; SUPT4H1; PAX8; BRD8; PA2G4; FHL2; ZNF410; SOX12; TFAP4; NCOR1; ADRB2; YEATS2; AEBP1; ZNF783; SP1; ZNF22; NR2C1; EED; RORC; HTATIP2; RAD21; KLF7; NFKBIB; VPS72; ID3; TAF5; AES; IRX4; RFXANK; ZNF652; SAFB2; REXO4; SOX15; FOXI1; SMARCC2; SETD3; POU2AF1; CENPF; ZBTB20; LPIN2; RNF111; TBL1XR1; CTNNB1; MYT1; KLF6; TFAP2A; VGLL4; CREG1; MECOM; ZNF24; ZNF574; HBP1; RFX5; CTBP1; PLAGL1; RCOR1; TFCP2L1; PITX1; KDM5D; INSR; HOXB6; RHOA; ZBTB7A; HOXA11; ACTL6A; GMEB2; SIX6; ZNF551; MYRF; CHD4; ZNF23; HIPK2; LHX1; RBL2; EWSR1; PCBD1; SUB1; HOXA10; HOXA7; ZBTB1; ZNF587; CEBPD; RUVBL1; CCNC; TCEA1; DDX5; PSMD9; YBX3; HOXB2; ZNF148; MED1; CDC5L; TFCP2; CNOT3; ZNF155; SMAD5; CDK7; ETS1; ELK3; BCOR; VEZF1; SKI; ZBTB24; AIP; THRA; TRIM16; NCOA4; DDIT3; SIX1; ZBTB11; TRRAP; NOC2L; BRIP1; NR0B2; NFE2L3; PIR; XRCC6; TAL1; DNMT1; MNAT1; RUNX1; E2F3; JUN; HSF2; SMARCB1; SOX13; HOXD11; SAP18; NR1H2; TRIP4; PPRC1; ZNF217; DEAF1; ZNF672; ZNF394; MXI1; ZFHX3; REPIN1; PSMC3; SP110; FOXO3; MAFG; BRD2; MED24; ZNF7; ZNF692; NFIX; CBFA2T2; ZBTB38; ARID1A; TEAD1; ZNF281; KLF2; EDF1; TAF5L; MED16; TCF21; TMF1; TGIF2; PIAS1; CREBZF; DDX54; TRIM33; CEBPB; UIMC1; BAZ2A; CHD9; ZNF143; SMARCA5; MGA; NFAT5; ETV5; RB1; PNRC1; ASCL1; TLE1; TAF11; ZNF83; CARM1; HOXB9; BIRC2; BRD7; NUP62; SIM2; PURA; POU4F1; MED15; RCOR3; ZNF593; SNAI2; SUV39H1; HMGB1; ZNF165; FOXO1; ZMYND11; YAP1; KLF11; NR0B1; WHSC1; ARID5B; ID1; CITED2; ZNF573; TCEB2; CCNE1; RBFOX2; ABL1; NR1D2; BANP; ZNF432; BCLAF1; VDR; TRIM22; RNF10; TRIM28; ATF3; ITGB3BP; ZNF473; C1D; SSBP2; CALCOCO1; UBE2L3; TCEA2; CUX1; ZNF516; ELF5; RFX7; TGFB1; ZNF232; HLTF; CCNH; ZFP36L1; HOXA5; FLNA; FOXD1; MITF; MAFB; SOX9