Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76635	Gsk-2126458	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	229	TRPS1; GATA3; NAB2; TFAP2C; ARNTL2; EYA1; ZNF623; TCF7L1; KDM5C; FOXF2; ERBB4; NFKB2; CREM; NHLH1; HDAC11; CERS4; NFATC4; TFDP3; TEAD3; TSC22D3; CRYM; NR4A2; FOXA1; VAX2; KLF9; SSBP2; HABP4; HOXD1; ZKSCAN3; ZNF175; WNT4; KDM4A; RARG; MAP3K10; ATOH1; BCL11A; MEIS2; HOXD3; ALX4; ARRB1; FOXF1; PCGF3; TAF1C; SHOX2; CBX2; LIN28A; CBFA2T3; SMAD3; NEUROD2; TBX21; TP73; PRDM14; NCOA2; HBP1; IRF5; ZSCAN31; STAT4; NR2F1; LHX3; NEUROG1; DYRK1B; CREB3L2; TBX3; ID4; ZNF117; DBP; ZIC1; SMAD6; SOX13; ZIC3; CREBL2; TULP3; DACH1; CBX4; ZEB1; E4F1; GBX2; ZNF107; ZNF394; ZNF93; NKRF; ZNF331; TOX; PBXIP1; NFE2L3; MAF; ZNF16; MED12; SOX3; SMARCA1; FOS; THRA; SPDEF; OSR2; ZNF816; BNC2; STAT1; NANOG; TFDP2; RING1; AR; WWP1; JAK2; LOXL2; IRF4; ZFPM2; CAMTA1; SREBF2; FOXH1; PNRC1; ZNF74; IRF9; ZNF85; PRDM2; CSDC2; HOXC4; GATA6; CHD9; ZNF215; HSF1; ZXDC; THAP10; MYCN; GTF2F1; NR4A3; TFAP2A; CDK2; CNBP; MECP2; SOX2; NFE2L2; PRRX1; ZNF141; SSBP3; VGLL1; ZBED1; CALCOCO1; BARX2; ZNF253; ZSCAN16; ACTL6B; ZNF148; PAX6; CITED2; ZNF160; ZNF124; TGFB1I1; TCF7L2; HOXB1; RARA; ZNF665; TGIF2; DLX4; PHIP; HHEX; CUX2; NR0B1; HIRA; THAP7; HOXB5; PFDN5; ATF3; HOXB6; ZNF611; ZHX2; NFE2; E2F8; TAF1; ZNF423; ZNF33B; TERF1; CREB1; RAD21; ZNF467; PBX1; DAXX; ARID5B; OLIG2; ESR1; MYBL1; NR2F6; IRF7; RBFOX2; ZNF136; MYRF; POU2AF1; ZNF264; CBX7; KAT2B; PAX5; ZNF721; REL; YEATS2; HOXB2; MNDA; JUN; PSMC3; ETS1; ARNT2; IRX5; TCF4; HOXB13; UBE2L3; ELF5; TCEA2; NAB1; BHLHE41; SALL2; ZNF43; PBX3; NCOA1; BTG1; INSR; IRF6; CITED1; FOXC1; ZBTB16; VPS72; TBL1X; CCNH; NR4A1; TWIST1; KLF2; DLX5; SOX17; RB1; ZNF91; NR1H2; KAT6B
Down-regulation	286	FOSL1; PSMD9; TBP; BTF3; TAF9; CEBPG; TCERG1; HDAC6; MSL3; C1QBP; IKBKAP; PLAGL2; TSC22D2; MYC; SAFB2; DNAJC2; ZFP36L2; BRD8; CCNC; MAZ; ZNF146; TFEB; ZBED4; RCOR1; PRKDC; SAFB; ERF; EWSR1; RBM14; MLX; BAZ1A; TRIM28; RBBP4; CEBPZ; NUP62; NKX3-1; CIC; SOX15; SFPQ; HCFC2; RUVBL2; PPRC1; ADRB2; VEZF1; KAT7; ZNF212; CRY1; SIX2; ZNF83; USF2; ZBTB24; GABPA; C1D; DRAP1; SMARCA4; MDFI; HSF2; TOB1; SETD2; CAPN15; UBE2I; CTNNB1; FOXN2; MAGED1; SP2; NFYB; SMARCC1; ELF2; PA2G4; CCDC59; PAXBP1; TTF1; MTF2; ELK3; ZNF281; CRK; ZNF532; ZNF783; APEX1; ARL2BP; PTTG1; BAZ1B; SAP30; ZBED2; ILF2; USP22; ZNF764; UIMC1; YBX1; DDX5; CBFB; MTA1; RBBP5; ELK1; MBD2; MED6; ZNF468; YWHAB; TAF4; TFAM; MYCBP; ZBTB7A; ZHX3; ZNF222; TSC22D1; ARNTL; HNRNPD; PHF2; NEDD8; CLOCK; POLR3F; GTF3A; PCBD1; RFX7; SMAD5; SUV39H1; SOX9; TFCP2L1; GTF2A2; MED1; HMGB3; CHD1; EZH2; PIAS2; ZNF211; MTDH; AATF; RBBP7; ETS2; RNF141; RUVBL1; NR1I2; EED; SMARCE1; ANKRD1; PMF1; RHOA; ZBTB11; HCFC1; SP110; MAFG; DR1; HDAC2; SCAND1; CEBPA; RUNX1; CBX3; YAF2; RNF10; ZNF8; TRIM33; VGLL4; CREBZF; ZNF593; TMF1; TP53; STAT6; GTF2IRD1; HMGB1; HTATIP2; BRPF1; TCF12; BCL11B; CDK8; SNW1; RNF6; REXO4; PQBP1; PSPC1; ZNF143; ZMYM2; TLE1; TRIP4; PCGF2; NRIP1; KDM5D; NFIB; CARM1; PATZ1; ARID4A; BIRC2; ID1; CCNA2; ELF1; MEOX2; E2F3; NCOR1; AFF4; BCL10; CSDE1; REST; AFF1; NFKBIB; TBL1XR1; ZNF552; AGO2; ZNF23; FOXO1; BTAF1; IRF2; LPIN2; NCOA6; ZNF337; CTBP2; ZNF302; KLF6; ATF5; MED27; HOXA10; ZNF410; WDR77; NRBF2; HDAC1; THAP1; BRD7; NFAT5; KAT8; PURA; POLR2A; RBM39; KMT2B; ZNF226; WHSC1; CNOT2; DDIT3; SAP18; FOXJ3; TOPORS; ATF4; LEF1; MNT; PPARG; BCOR; SPEN; PPARGC1A; TFCP2; SNAI2; RBPMS; HDGF; DDX54; DEK; ZNF32; ORC2; PIAS3; ZNF432; EMX2; NCOR2; DPF2; PHF20; TAL1; ZBTB1; SMAD1; ERBB2; TAF10; ZMYND8; ZNF652; MNAT1; MLXIP; MSX1; ENO1; ZNF267; JARID2; BRIP1; ERG; SREBF1; MAFF; XRCC6; XBP1; RBBP8; TEAD1; EDF1; ATF1; PITX1; HMGA2; SUB1; FLNA; MAFB; NFATC3; MED24; WWTR1; ELF3; TGFB1; TCFL5; RUNX3; ASCL1; TFDP1