Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76634	Gsk-2126458	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	203	IKZF1; TRPS1; SOX3; FEZF2; FOXG1; TSC22D3; NFATC4; ZBTB16; ELF4; ZBTB3; ZNF623; ZNF701; ZNF254; ZNF34; ST18; ZNF91; SIX6; ZIC3; ZNF682; VGLL1; PBX1; BCL11A; EN1; TCF25; TCF7L1; ZNF780B; CITED2; ZNF695; HBP1; ZNF225; BNC1; HDAC9; GATA6; ATOH1; HOXA2; SCRT1; PNRC1; SPDEF; TP73; KLF9; ZNF214; POU6F2; ERBB4; ZNF500; ZNF671; TAF4; ZNF770; NEUROD1; SLC2A4RG; HINFP; E4F1; SOX2; NR5A2; ZIC1; ZNF257; CDIP1; SKIL; ZNF93; TFEC; EZH1; TULP3; RLF; FOXI1; HDAC5; EMX2; PRPF6; SCAI; POLR3C; LIN28A; ZKSCAN4; LHX2; SCMH1; ZFP69B; ZNF415; ZNF85; KLF13; RAD21; PRDM2; ZNF107; ZNF217; AR; SETDB1; SUPT3H; IRF9; RERE; ZNF350; ING4; PRDM14; ZNF721; HOXD1; CBFA2T2; HSF1; MED12; CBFA2T3; ZNF492; VPS72; AEBP1; TCEA1; NFIL3; RBPMS; ZNF141; TGFB1I1; ZNF688; PIAS4; TERF1; TCF7L2; ZNF250; RORA; NKX3-2; TOB1; PHIP; PSMC3; NCOA2; TCF7; NHLH2; INSM1; ZNF667; ZNF160; ZNF329; STAT1; CRYM; MEIS2; LITAF; CEBPD; DDIT3; MED14; ZNF74; PGR; MYT1L; SOX17; ZNF611; TFAP2C; KLF11; TXNIP; SNAPC4; HIPK2; OLIG2; OVOL2; ZSCAN18; ZNF654; BRD4; THRA; NFE2; MKL2; CREB3L2; BNC2; NANOG; ZFPM2; TOX; ESR1; TULP4; TTF2; NFE2L1; SALL1; PAX6; ZNF12; TCEB2; ZNF665; TCF21; ARID5B; ZNF467; MYBL1; SOX13; INSR; CREBL2; PLAGL1; ZNF268; ZBED1; YEATS4; MXI1; MYB; KLF4; NPAS2; ZNF165; JUN; ZNF232; SALL2; ATF5; TRIM22; WT1; ZNF512B; SNAI2; TOX3; PRRX1; CCNH; TLE2; SMARCD3; CITED1; ZNF117; DLX2; SSBP3; HOXB2; TLE4; FOXF1; HIRA; THAP11; ZNF423; RB1; ID4; HOXB6; HOXA5; ERBB2; OSR2
Down-regulation	264	PARP1; FOSL1; MYC; ESRRA; RBBP4; ETS1; EYA1; ZNF146; TRIM32; CTR9; ELK3; ZNF672; RBM14; ELK1; MLX; ADRB2; SIX2; PCGF2; HLTF; TRIM27; MLXIPL; CENPF; ETS2; TTF1; TBP; ABT1; BCL10; HDAC7; HNRNPD; DRAP1; GABPA; ZBTB11; TRIM28; NKX3-1; CEBPZ; RBBP5; IKBKAP; CBX6; NUP62; MYOG; SP1; NFRKB; PPRC1; TRIM25; MDFI; USF2; MYCBP; TCERG1; MAGED1; RCOR1; TCF12; IRX4; ZNF384; HDAC1; RNF14; NSD1; HMGXB3; CNOT1; MYOD1; PLAGL2; ZSCAN5A; PHF2; CHD1; ZNF212; EP400; SREBF1; PA2G4; PHOX2A; PHOX2B; ZBTB1; SFMBT1; PIR; SMARCC1; NCOA4; DDX54; SMARCA5; WHSC1; SNIP1; ZNF783; SP3; MED6; TBPL1; SETD2; ZNF614; DDX5; CRY1; HAND1; SF1; BAZ1B; SETD3; TRIP6; KAT7; IKZF5; ZFHX4; HIPK3; RNF138; NPAT; HMG20A; PPARG; CBFB; ORC2; ZBTB18; BCL11B; EGR1; SMARCD1; POLR2A; HES1; PSMD9; MLLT10; TCF15; SMARCA4; TCF20; PDLIM1; WWC1; ZMYND11; KMT5A; HOXC6; TEAD1; FHL2; RNF10; HOXA11; FOXC1; NFYA; BMI1; GCFC2; ARID4B; TAF10; MECOM; SFPQ; ZBTB43; TBL1XR1; ZNF443; TSC22D2; SUV39H1; GTF2IRD1; MEF2A; DR1; SNW1; PBRM1; ETV5; ZHX3; RNF4; TMF1; AATF; RNF6; ZNF84; ZNF266; TRRAP; BCL3; LIMD1; RUVBL1; CCDC59; GTF2I; RHOA; UBP1; USP22; PIAS2; TBX3; TSC22D1; TFCP2; URI1; TRIM16; RFX5; UIMC1; TRAK1; MSX1; SIM2; BAZ1A; HEY1; SSRP1; TP53; BRD8; REST; KDM5D; GABPB1; CTNNB1; CRK; MTA1; TFAM; ZNF134; BATF3; KDM2A; SMAD2; JARID2; CBX3; CDK9; HSF2; HOXA10; MNT; ANKRD1; SOX9; RUVBL2; NRBF2; PITX1; AGO2; XBP1; ALX1; BTAF1; MED23; ECD; BRPF1; MTDH; SMAD3; POU4F1; FOXJ3; FLNA; WWTR1; BAZ2B; SMAD5; CCNE1; VEZF1; CARM1; ID1; TAF7; ISL1; ASH2L; HMGA1; AFF1; ATF1; ZMYM2; SMARCE1; SIAH2; ZBTB38; MAX; NFAT5; ELF1; HMGA2; HMGN3; SIX1; CCNA2; PTTG1; GATAD2A; ZNF302; BRD3; HTATIP2; SERTAD2; CHD7; RREB1; MAFG; CBX5; MGA; ATF7IP; ZBTB20; FOSL2; DDX17; TBL1X; PREB; SATB2; NR4A1; AHR; YAF2; NFATC3; ENO1; BBX; BCLAF1; NR1D2; MXD1; NR2F2; ERG; IRF8; VDR; MED1; VGLL4; KAT6B