Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76619	Doramapimod	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	GATA3; TRPS1; MXD3; EN1; TEAD3; HES1; EYA1; RARG; TBX3; ETV7; CDX1; CBX4; HOXC8; TFAP2C; TULP3; NFKB2; PITX2; HIVEP3; SMAD3; RORA; GBX2; SP140; DBP; ZEB1; HOXB3; MNDA; ATOH1; CAMTA1; PROP1; ABT1; MXI1; PRMT2; HESX1; SOHLH2; FOXA1; ZZZ3; ZNF24; FOXF2; TP73; CBFA2T2; ATN1; KAT2B; POU4F1; ZNF623; NKX6-1; HOXC13; IL16; MBD1; DLX4; E4F1; TCF25; ZNF205; CNBP; GFI1; MYCL; RBFOX2; NHLH1; MEN1; HBP1; VGLL1; DNAJC1; SHOX2; KLF3; PHIP; ID2; THRA; HOXC11; SSX1; SNAI1; ARID5B; NFE2L2; WWP1; TRAK1; FOXC1; CREM; RNF138; TCF7L2; HHEX; TULP4; CSDC2; ST18; IRF6; SIX3; TAF5L; ZNF253; DLX2; CERS4; ZSCAN9; PRDM1; NR4A2; NR5A2; ZNF117; ZNF467; FOXF1; CD3D; PHOX2B; DAXX; MEIS2; ZNF148; ZNF354A; GRHL2; ACTL6B; ZBTB20; GATA6; ERBB4; ZNF74; ZNF93; THAP10; ZNF131; MAF; TCF4; NR2F1; USF2; CCNE1; NR2F2; PHF20; ZNF248; ZNF43; CBFA2T3; TDP2; OSR2; FOXK2; KAT6B; CREBL2; NCOA1; ZNF331; E2F8; NFE2; DEAF1; ARNT2; ZFP36L1; CREB3L2; RBPJ; HOXA10; PSPC1; ZFP36L2; JUN; NR2F6; SMARCA1; HIC2; JUP; HOXC6; TGIF1; GTF3A; PAX6; ZNF423; ZFPM2; HIRA; ELF5; TLE2; NFE2L3; MTF2; ATF3; CREG1; WT1; TGFB1I1; IRF8; ISL1; HOXC10; POU2AF1; INSM1; SOX11; HOXB7; RB1; MYBL1
Down-regulation	236	CRK; FOS; NELFB; TRIP6; LITAF; FOSL1; FOSB; HDAC6; RBBP5; SAFB2; STAT6; ZBTB7A; TTF1; EMX2; REXO4; NFIB; PLAGL2; CTR9; ING3; CTNNB1; ZNF668; RBPMS; JUND; NKX3-1; MED6; TFEB; HIPK3; TSC22D2; MAZ; ZBTB11; PRKDC; MKL1; TRAF6; RUVBL2; TFCP2L1; RFC1; CRYM; EZH2; ZNF432; BRD4; E2F5; CEBPZ; ZNF222; ZNF212; MED27; ZBTB18; HIPK1; TRIM28; ERCC2; SIM1; TBPL1; FOXN2; PPARG; ASXL1; PHF8; RBL2; KLF7; ATF2; CNOT1; SFPQ; ZNF143; C1D; VEZF1; SMARCA2; RUNX1; HIPK2; SATB2; ZNF576; SOX15; CHD8; SND1; BRCA1; SALL1; ZNF281; ADNP2; BAZ1B; YY1; PTRF; NUP62; ZNF165; ZBED4; MED25; CTBP1; EED; RBBP7; PPARGC1A; MED14; HCFC2; TAF9B; RBM14; PMF1; MAFG; TBP; UBE3A; ZHX3; NR1H2; SETD3; REPIN1; XRCC6; PSIP1; ZNF189; NCOR2; TAF4; NCOR1; CUX1; FOXO3; TADA3; BRF2; MED1; TXNIP; CREB3; ZNF8; WHSC1; NFE2L1; ADRB2; JARID2; SMAD5; EP300; TAF10; SAP30; TLE1; ZNF394; TP63; TMF1; RRN3; CCNH; TFAM; HDAC9; NFIC; ZNF419; CENPB; PATZ1; NRIP1; USP22; TSC22D3; SIX1; THAP1; SUV39H1; KMT2B; ZNF721; GATAD2A; TCERG1; HSF2; ZNF135; AFF4; REST; YWHAB; WDR77; ORC2; TLE4; EWSR1; RFX7; RNF141; TSC22D1; ARNTL; KLF6; PDLIM1; ZNF587; MNT; CRY1; TSG101; BASP1; CARM1; EHF; RXRA; NCOA3; TFE3; BRIP1; KLF11; PCGF2; MNAT1; HDAC4; TAL1; KAT5; BIRC2; FLNA; ID1; PHF2; NEDD8; SMARCA4; KDM5D; TFAP2A; BTG1; TRIM16; CREB5; ELF1; TAF1D; SUB1; ZKSCAN1; TFCP2; KAT7; IRF9; ZNF593; ZNF473; TOB1; BAZ1A; BRD2; RCOR1; ATF5; TOX; MYRF; CERS6; VDR; SOX9; MITF; PBX1; CHD7; AATF; TCFL5; SCAND1; STAT3; STAT1; ZNF274; BAZ2B; ERG; BRD3; ZNF264; HMGA2; TOPORS; PEG3; FOXO1; AFF1; SALL2; FOXD1; ID3; ASCL1; ABL1; MAFB; MSX1; ZNF589; VGLL4; HTATIP2; SATB1; MLXIP; HOXA5; LEF1