Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76618	Doramapimod	GSE92742	MCF10A	Human	6h	10uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	183	TRPS1; NFKB2; SCMH1; STAT4; CAMTA1; CNOT3; ZXDC; E4F1; TCF25; TCF7L1; MNDA; TERF1; CBFA2T3; ZNF711; ZNF239; IKZF1; RARG; NANOG; TCF7L2; BPTF; FOXF2; PCGF3; GRHL2; ZNF682; TFAP2C; TEAD4; RSF1; ZNF74; KLF4; ZNF93; THAP4; FOXF1; NEUROD1; ZSCAN31; GATA6; HINFP; LIN28A; PAWR; NKX3-1; THAP10; SREBF2; MEF2A; PRDM2; EN1; PITX2; AR; ZIC3; BCL6; TFDP2; SMARCA1; NR3C2; ZNF623; TAF4B; ZNF253; RORA; ID4; CITED2; NR4A2; CDX1; CREM; CD3D; ZNF835; TEAD3; SMAD6; CBX5; ZNF85; HIRA; SPDEF; ZNF443; URI1; ZNF91; IRF1; DAXX; DLX4; CBX7; TULP3; ZEB1; PRDM14; YAP1; HSF1; TRIM24; ERBB4; INSR; TOX; YEATS2; ZNF573; ZSCAN9; MAF; HDAC5; TAF5L; ZNF141; PHF1; ZNF331; TBL1X; NFE2L2; DBP; ZFPM2; DACH1; CRYM; TGIF1; ESR1; BNC2; TRIM22; SOX4; NFATC1; CBX4; GTF2F1; GTF2I; MYBL1; ZNF117; E2F5; MED13; ZNF248; RBPJ; CSDC2; SOX2; ZNF415; FOXE1; TOX3; ZNF112; SP140L; BACH2; ZNF22; TCEA1; NR0B1; AEBP1; NR5A2; IRF9; IRF6; ZNF124; EMX2; ZZZ3; COPS2; CREBL2; MYT1L; ZNF43; HIC2; ZNF264; PFDN5; NFE2L3; CREB3L2; MYCL; MAGED1; PRRX1; ARNT2; KAT2B; RREB1; WT1; NR1H4; SSBP3; EYA2; POU2AF1; IRF7; ZFP36L1; ZBTB38; SMARCD3; CREB1; ZNF665; ZHX2; ZNF423; PHIP; MEIS2; STAT1; TGFB1; ZBTB20; NR1D2; ZBED1; JUN; KAT6B; HOXB2; PSPC1; TBX3; LEF1; SALL2; ARID5B; BHLHE41; SOX11; ZIC1; ATF5; HLF; RB1; PEG3; OSR2
Down-regulation	222	LITAF; NFKBIA; PSMD9; ELK1; MECOM; FOSL1; MLXIPL; HDAC6; STAT6; WWC1; ARNTL2; SIX2; ETV1; SNAI2; THRAP3; SMARCA4; TAF10; BLM; TFEB; CRY1; BRCA1; GATA4; RBBP5; MLX; MBD2; PCGF2; PMF1; SOX15; ZNF593; ENO1; ASH2L; TBP; TCERG1; CTR9; PHOX2A; MED6; ZNF468; PTRF; MYBBP1A; FOXA2; MYCBP; ZFP36L2; PRKDC; MED1; RFX5; RNF141; MAZ; UIMC1; MDM4; TRIM16; BCL10; HCFC2; GTF2A1; JUNB; EED; ZHX3; FOXO3; ING3; ADRB2; ZNF432; ZBTB7A; TSC22D2; HDGF; PCGF1; ELF4; ZFX; EGR1; WDR77; ZNF672; ZNF281; BAZ1B; BRF2; HSF2; NUP62; NELFB; IKZF5; VDR; CASZ1; MAFF; SMARCA2; ZFP64; RBBP7; SNW1; ATF1; ZNF614; NFKBIB; PBX3; HES1; TP63; TRIP6; MNX1; PTTG1; KDM5B; TP53; PDLIM1; TTF1; ZNF410; TMF1; BRD8; CRK; UBE2I; RUVBL2; HR; RFX7; AATF; ZNF516; TSC22D4; NFIB; SMAD3; ZNF140; ANKRD1; SUV39H1; TAF1D; HIPK1; SAFB2; DR1; TSC22D3; GMEB2; ZNF274; RBBP4; CCDC59; ORC2; HTATIP2; SFPQ; SPEN; MYNN; TRRAP; C1D; SOX9; MEIS1; BIRC2; TWIST1; SETD2; BAZ1A; NCOA6; RHOA; ASCL1; NRIP1; SIX1; CBFB; KAT6A; ETV4; FOSB; YBX1; BRPF1; MSC; PPARG; DDX54; MED27; ZNF143; HLX; HEY1; PREB; TTF2; BCOR; ZNF532; SCAND1; ZNF267; HMGA1; ZNF23; BMI1; ZNF131; PIR; ZNF652; MAFG; RBM14; EDF1; MYRF; NR1I2; USF2; WHSC1; TBL1XR1; PPARGC1A; HDAC1; YEATS4; MTF2; ID3; NR0B2; MTDH; TOB1; TRIM29; BASP1; RUNX1; DDIT3; TCEB2; FLNA; NEDD8; RCOR1; NRBF2; SHOX2; USP22; NCOR2; MSX1; SERTAD2; BAZ2B; YWHAB; ZBED2; ABL1; BATF3; PAX5; KLF6; TCFL5; ELF1; FOXO1; MNAT1; PEX2; MITF; ZNF226; FOXD1; PIAS2; KDM5D; ISL1; ZKSCAN1; NFATC3; ERBB2; INSM1; CCNH; VGLL4; TXNIP; FOXC1; HOXC6; SATB1