Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76616	Ldn-193189	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	332	GATA3; TBX2; TRPS1; NFKB2; SSBP2; ZNF536; SIRT7; ATOH1; ZBTB17; KAT2B; ATN1; ZXDC; SOX5; ZNF446; SNAI1; ZMYND8; TEAD3; HOXD1; ZNF623; ZNF44; NR4A2; ZNF174; SMAD3; PPARD; HOXC8; NEUROD1; ZNF124; KLF15; POU2F1; SOX4; NAB2; CBX8; KDM4A; NR2F1; ZBED1; FOXF1; SALL1; ZNF3; HABP4; RORA; RFX2; MYCN; ZNF253; NHLH1; ZNF580; HHEX; PIR; CREB3L2; SP140; THRB; SUPT6H; RNF138; MBD1; ZNF45; ABT1; HDAC11; ELF4; PCGF3; TRIM32; SOHLH2; NEUROD2; ETV7; NEUROG1; PRDM12; THAP10; RBBP7; MXD4; HOXA11; NRL; E2F2; ZFPM2; HOXA3; E4F1; THAP3; STAT5A; MAP3K10; CBX4; HMGXB4; EHMT1; ZNF507; ZBTB44; ZIM2; CDYL; HESX1; BATF; WWP1; ZNF180; NR5A2; RXRG; PBX3; ZBTB20; NR5A1; ZMIZ1; SPIB; GBX1; NCOA1; ZFP30; PHF20; CREM; ZNF589; ZNF721; FOS; PLAGL1; AR; ZZZ3; ASXL1; HNF1B; VGLL1; LHX3; USP21; EP300; PRPF6; TCF7; ZNF211; SOX10; ZNF423; TRIM24; KLF4; SHOX; DR1; HOXC11; MAF; MYCL; OSR2; GATA1; TULP4; HOXB7; ZFP64; ZEB1; NFKB1; SSX3; SOX21; CERS4; ZNF611; DLX4; EYA1; FOXF2; FEV; PRRX2; GLI1; PRDM1; PRDM14; DAXX; WNT4; ZBTB14; NR2F2; CDX1; DBP; TRIM25; CSDC2; STAT5B; NR1H4; ZBTB38; EN1; ZNF175; SMAD6; CBX7; LIMD1; IFNB1; WWTR1; PHIP; ALX1; TUB; BACH1; CAMTA2; TFDP2; IRF5; ZNF160; KDM4C; DLX5; ZNF506; RELB; ELF2; FOXK2; IRF4; ZNF443; ZNF701; ARID5B; ZNF14; BCL6; ZNF16; WT1; ZNF43; PITX2; RORC; PRDM10; PRDM2; SSX1; AHR; CHD2; HOXD3; ZNF112; PRDM4; HOXB5; ZNF248; RARB; CBX6; CBFA2T2; PEG3; CUX1; DACH1; TCEA1; ING1; MEIS1; ZNF235; TFAP2C; BBX; ZNF93; ZSCAN31; EN2; KDM5D; SP2; ZNF768; ETV6; PKNOX2; HMGA2; TOX4; ZNF264; NPAS2; ST18; RARG; FOXC1; ELK3; PAX6; BARX1; SRF; HMGN3; SPEN; MBD2; ELF5; REL; ZNF34; PLAG1; SOX3; ZNF33B; GATA6; HMGA1; IKZF5; RING1; ERBB4; STAT4; ELF3; IRF9; REPIN1; ZNF512B; RERE; RBFOX2; ZNF665; ERCC3; FOXE1; ZNF134; SOX13; NFATC1; RBL1; TBX3; MGA; SMAD2; SERTAD2; NR3C2; ZNF7; PDLIM1; GCFC2; ZNF816; HLF; ZKSCAN7; ZNF133; MTA1; ING2; RCOR3; THAP7; ADNP; HOXB2; SP100; ATF5; PROX1; HOXA10; TBL1X; ZNF562; ZNF250; ZNF266; CCNE1; MNDA; MYBL1; TOX3; ZNF12; HOXB6; GRHL2; STAT1; ZNF117; TCF21; ZNF688; NR4A3; TRAK1; HOXA5; MEIS2; HMGB2; ARID4B; CXXC1; IRF8; ACTL6B; TOX; NANOG; TLE1; ID4; ZHX2; FOXN3; HDAC4; NFE2L3; CREB1; STAT3; TGIF1; SAP30; NCOA6; IRF7; POU2AF1; ZNF131; PAX5; MITF; ELF1; ZFP36L1; ESR1; ZNF331; HTATIP2; THAP11; TGFB1I1; JUN; ZSCAN18; NR1D2; BHLHE41; BTG1; NFATC3; SCAND1
Down-regulation	352	FOSL1; HDAC2; C1QBP; RHOA; TCERG1; RBBP5; SUPT4H1; CRK; GATAD2A; MLX; EZH2; LOXL2; TAF10; RLF; PPRC1; RUVBL2; STAT6; TAF9; HMGB3; TAF7; PSMC3IP; TRIP6; SOX15; CTR9; CTNNB1; RUNX1; TSC22D2; MED6; DDX5; WWC1; LITAF; SSRP1; SETD3; CSDE1; NFYB; UBE2I; CCDC59; RRN3; RBBP4; HDAC6; IRX4; BRD8; EED; SNW1; MLXIPL; ETS2; ELK1; PAXBP1; ZBTB7A; KAT8; IFI16; EMX2; HLX; KDM5B; ZBTB11; PRKDC; CEBPZ; BRF2; BTAF1; CNOT3; ZNF83; MSL3; TTF1; NR2E1; ZNF692; NKX3-1; NELFB; TAF1D; ETS1; TBP; TCEB2; CAPN15; MED1; ZNF281; ASH2L; CCNC; CBFB; LDB1; MBD4; ZNF205; HIVEP2; RFXANK; HCFC1; RBPMS; ZNF302; ZNF155; USP22; FEZF2; MECOM; GABPA; MED24; ZNF410; MYBBP1A; THRAP3; BCL11B; CTBP1; FLI1; PHF8; PTRF; ZNF669; POU4F1; PBX2; CREBZF; HIPK3; ZNF528; MAFF; ZNF146; TERF2; GMEB2; FOXA1; CEBPB; NSD1; TCF12; RELA; EGR4; CEBPE; BAZ1A; TAF11; BTF3; ZNF165; ZNF646; FOXO3; SAP18; ZNF263; CALR; MED23; TADA3; SAFB; ZNF587; TTF2; ZNF529; ZNF574; TAF1A; MMS19; SIX1; MYBL2; AEBP1; TCF3; SNAI2; DNAJC1; TAF5; YBX3; RFXAP; AFF4; EHMT2; BRCA1; HSF2; RYBP; TAL1; DDIT3; ZNF672; BRD2; SAFB2; GTF2A1; CNOT2; USF2; FLNA; ZNF107; VDR; RBBP8; CNOT1; E2F3; ZHX3; TCF25; SMARCD2; UBE3A; RCOR1; CEBPD; NPM1; KLF6; MED21; ADRB2; RBM14; BAZ1B; TRIM27; ZNF432; NFKBIA; ZNF177; TDRD3; ZNF460; BRIP1; LPIN2; THRA; MDFI; ZNF232; BRD7; FHL2; TFE3; DMTF1; GTF2F1; MED7; BRWD1; IRF1; PARP1; ZNF384; KAT2A; MNAT1; NR2C1; UIMC1; TFAM; TRIM28; NUP62; BAZ2A; ZNF32; MAML1; IRF2; ATF2; GTF2IRD1; NFIL3; PPP1R13L; SHOX2; JUP; ZNF354A; ZNF140; PTTG1; HIRA; NR1H2; PA2G4; SUB1; MDM4; TSG101; RBL2; CLOCK; NFIX; ORC2; KLF7; JUND; WHSC1; MED27; ILF2; SND1; FUBP1; NRIP1; RFC1; SPDEF; VGLL4; ECD; PITX1; EHF; CCNA2; MED20; TWIST1; KLF2; SIM2; KMT2B; PSIP1; ZNF468; KAT7; TFCP2L1; TRIM29; RBPJ; CRYM; EP400; ZNF23; NR1I2; APEX1; ZNF667; DDX17; UBE2L3; ZNF184; RNF14; SMARCA5; HSBP1; ZNF274; SUPT3H; GABPB1; CUX2; NFE2L2; SMAD5; POU3F2; TAF9B; HMGB1; BRPF1; PBX1; MED13; SFMBT1; ACTL6A; PNRC1; PURA; TFAP2A; ERG; PSMC3; COPS5; TRRAP; ZMYM2; NCOR2; ZNF143; CERS6; TDP2; POLR2A; CIZ1; ZNF652; TBL1XR1; NKX2-1; ZNF426; MED17; RFX7; TFDP1; NFATC4; EGR3; MKL2; NFIB; ASCL1; CCNH; SFPQ; TSC22D3; CITED1; SIX2; ZNF84; SOX11; ZNF267; ID3; ZKSCAN1; ZBTB1; XRCC6; FOXJ3; ID1; GLI3; HOXB13; POLR3C; ISL1; MYCBP; MAX; CREB5; CHD3; JUNB; SALL2; PIAS2; ZBTB16; CBX5; SMARCA2; TSC22D1; ABL1; TP53; NEDD8; ZNF532; YEATS4; MNT; MSX1; LEF1; ERBB2; NRBF2; HOXC6; ATF3; KLF5; BCL3; TCFL5; SIAH2; DLX2; RUNX3; FOXO1; FOSL2