Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76615	Ldn-193189	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	342	IKZF1; TBX2; NR3C1; HDAC6; FOXG1; PPARG; E2F2; EYA1; SOHLH2; ZNF446; PHF1; ZXDC; MDM2; ZNF580; FOS; KDM4C; PAWR; CEBPZ; TFAP2C; TCF7; SSX3; RFX2; GFI1; HNF1B; FOXO3; ZMIZ2; ARID5A; ZBTB44; TAF4; ZNF211; KDM5A; FOSB; SATB2; RELB; DMRT1; DLX4; SHOX; KLF12; ELF3; HDAC4; RING1; NFE2L3; SSX1; CD3D; NHLH1; ATOH1; DBP; LIMD1; TRIM24; PRRX1; USP16; MZF1; LHX3; TFDP2; HOXD1; NANOG; ZNF443; RXRB; TXNIP; DMTF1; NFKB2; STAT4; ZSCAN32; HEY2; MYCN; MNDA; HESX1; NCOA1; ZBTB14; EN1; TBL1X; EHMT2; NFRKB; CTBP2; E4F1; TRIM32; ZNF184; TERF1; ZNF208; ZNF423; IRF5; ZNF711; PRPF6; HOXA3; RBPJ; STAT5B; ZNF324; FOXC1; HDAC11; SLC2A4RG; DNMT3B; PHIP; HMG20B; SP140L; MTA1; NPAS2; SP3; GLI1; RFX5; ETV5; SMARCA1; MYCL; TOX; STAT5A; HOXC11; CREM; DACH1; ZNF292; CBX7; HAND2; BPTF; PMS1; SOX2; HMGN3; EZH1; ZNF574; RORC; TLE1; HABP4; BATF; LHX6; NR4A2; SRF; ZFP64; AIRE; LMCD1; WT1; HOXD3; SNAI1; ZNF552; POU2F1; BRDT; HEY1; MYOG; ZKSCAN3; ZNF329; FOXF1; MAF; ZNF467; JAK2; KDM5C; CAMTA2; HIF3A; PRDM5; CBX6; TLX1; KMT2D; SP2; ALX4; TULP4; CUX1; MECOM; OSR2; CIITA; IRF4; ZNF45; ZBTB17; PIAS4; ZBTB38; ZNF507; TCF7L1; MYBL1; BARX1; POU6F1; PAX2; MYOD1; ZIM2; FOXJ1; LIN28A; NFIL3; THAP7; PBXIP1; MKL2; VENTX; RBL1; KLF11; DAXX; ZNF701; GATA2; POU2F2; SAP130; WNT4; ZBTB25; RUNX3; KAT7; DLX2; NCOA2; IKBKAP; BANP; FOSL2; BRD2; ZNF562; VGLL1; ZNF202; WWTR1; TAF1C; REPIN1; ZNF506; HSF4; OVOL2; TRIM33; HMGXB4; MNX1; KLF9; SMARCC2; NCOR2; SOX3; ING1; CBFA2T3; STAT3; DYRK1B; YBX2; ZNF331; GATA6; INSR; CREB1; TAF4B; HOXC10; NR0B1; CREB3L1; SPDEF; ZFHX3; ZNF16; ERCC2; ZNF217; MYB; BBX; SNAPC4; MLXIP; RARA; MEIS2; OLIG2; CBX4; TRPS1; BLM; HAND1; NFYC; TRIM27; HOXD11; NKRF; RBPMS; ZNF76; ZZZ3; WWC1; BACH1; ZKSCAN7; SP140; ZNF512B; FOXN3; ZNF215; PSIP1; ZNF200; PRDM14; POU3F1; ANKRD1; MYRF; ZSCAN16; RARB; TCFL5; HMBOX1; PGR; POU5F1B; BCL11B; EBF2; LZTR1; DLX5; ARID5B; SOX13; ERG; HHEX; ZNF195; NR3C2; SREBF2; KLF2; KAT6B; NR5A2; MTF2; POU2AF1; ZNF257; ZBTB20; ZNF93; MED7; THAP10; SALL1; DEAF1; NKX2-1; ZNF180; PURA; SMARCA2; HSF1; BCL3; TRIM16; HOXA10; SSBP3; IKZF5; POU4F1; SATB1; ABL1; KAT2A; KLF4; PIAS3; IRF9; ZMYND8; EPAS1; MEN1; URI1; SIX3; HOXC4; NR1D2; ZNF654; THAP11; KLF6; ARID4A; CARM1; ZNF33B; ZNF267; PLAG1; BRD3; BMI1; JARID2; NR2F1; SIX1; ZNF117; ERBB2; ELF5; TP53; EYA2; PRDM1; HOXA1; FOXF2; KLF13; HTATIP2; PEX2; ASCL1; TGIF1; ID4; AHR; IRX5; ELK3; JUN; SCAND1; HOXC6
Down-regulation	356	PCBD1; RAN; HDAC2; PSMD9; STAT6; CCNC; RBBP5; COPS5; MED6; KAT8; CEBPG; SMAD4; CREB3; RNF138; ARID4B; GTF2IRD1; PLAGL2; MSL3; CTNNB1; TTF1; MED17; ZBED4; ARHGAP35; CTR9; RHOA; NFIC; CCNT1; MED23; EED; KDM5B; L3MBTL1; FOXA1; FOSL1; ZBTB7A; XRCC6; KAT6A; IRX4; RYBP; CRK; UBE2I; EMX2; CERS6; BRF2; C1QBP; TBL1XR1; FUBP1; BAZ1A; TFAM; TSC22D3; DNAJC2; ECD; HIRA; ZBTB43; BAZ1B; CCDC59; ZNF410; PPRC1; IFI16; NCOR1; ZNF32; ILF2; TAF1A; ZNF426; ZNF394; PITX1; MLXIPL; PSMC3; ARL2BP; TBPL1; BTAF1; ZFP30; MYBL2; MED24; ZBTB11; CCNH; ZKSCAN1; CAPN15; POLR3F; NCOA4; SOX15; APEX1; GFI1B; GATAD2A; CBX3; ZNF83; TSC22D1; RBM14; ATF3; SAFB; UBTF; CBFB; CALR; UBE3A; MMS19; TCEA1; REXO4; SMARCC1; LMO1; ZNF667; TRIM29; TERF2; ETS1; SFPQ; MLX; UBE2L3; MAX; ZNF140; COPS2; PRKDC; GTF2A1; SCMH1; LDB1; ZNF532; RBBP4; TSHZ2; DDX5; TRIP6; MAZ; VPS72; SIRT2; ZNF135; CENPF; TRIP4; HOXB2; CDX1; MED15; ZFX; RFXANK; AES; ZNF669; ZNF432; SSRP1; TFAP2A; TBP; ZNF652; NUP62; SMAD5; KAT5; ZNF146; MEF2D; HBP1; ATF2; RNF111; UBE2B; TRIM22; TCF12; SREBF1; SETDB1; HIPK3; HLX; BLZF1; SMARCE1; BRD7; HDAC9; ZNF468; EZH2; ZNF10; HIVEP2; GATA4; RSF1; CDK8; SUMO1; HDGF; BRD8; YWHAB; NFIB; CITED2; PRDM4; TAF10; PCGF2; ZNF430; MBD4; ZFP36L2; ADRB2; CCNA2; MAFF; ENO1; ZHX3; ADNP2; RFXAP; TAF11; ZSCAN12; PBRM1; ZNF573; ZNF302; CREG1; PSMC3IP; PTRF; ZNF177; CHD4; ATF1; IRF8; ZNF576; NONO; KLF1; ZNF12; TSG101; PBX1; ZNF175; JUP; RNF10; CCNE1; NELFB; SAP18; SETD3; NR1H2; PHF8; SMAD3; ATF4; NR4A1; ZNF239; GABPB1; DEK; SMARCA4; ZNF274; VGLL4; NFYB; ASH2L; MED27; KLF7; SMARCD2; ZNF529; CDK7; ID3; NFX1; HR; SNAI2; TP63; TOB1; JUND; ERF; MED16; ZNF551; TAL1; HOXB6; NFE2L1; RRN3; NRIP1; NFE2; AGO2; HMGB2; PEX14; AIP; FLNA; MED4; VDR; PEG3; TEAD1; SMAD1; SCAI; RFX7; SOX11; ZNF672; ZNF189; MEOX2; BACH2; NKX3-1; HDAC5; UIMC1; MTDH; MED20; CDK2; BASP1; CITED1; ZNF143; ZNF593; ZNF84; SUV39H1; FHL2; DDIT3; CNOT2; TFCP2; PNRC1; TCERG1; CDIP1; TMF1; KLF5; TCF4; SRCAP; ZMYND11; HOXB13; TGS1; NPM1; ISL1; PQBP1; HMGA1; CTBP1; YBX3; ZNF304; NR1H4; HMGB1; TRRAP; MYNN; MITF; RBBP8; PMF1; ZNF131; PFDN5; SPIB; KDM5D; SP100; SIAH2; HMG20A; LEF1; ID1; ZNF23; CHD9; STAT1; MXI1; NFAT5; ZNF112; RCOR3; NHLH2; SPEN; SOX9; CSDE1; MAFG; ZNF124; ORC2; NFKB1; TFE3; IRF1; YAF2; YEATS4; HOXB5; SSBP2; FOXK2; AATF; RCOR1; USP22; GLI3; MEIS1; ZBED2; TCF21; NR4A3; EHF; FOXJ3; SAP30; BCLAF1; NEDD8; FOXO1; ZNF665; CRY1; NFATC3; PHF20; ZNF91; HOXA5; ST18; DDX17; PDLIM1; ATF7IP; SERTAD2; HOXB7; HIC2; SOX17; ZNF589