Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76613	Celastrol	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	IKZF1; TRPS1; ETV5; NAB2; ARID3A; CD3D; CCNE1; TCF7; CBX4; EN1; MDM2; ZNF512B; ARID5A; TFAP2C; PHIP; PAX6; SP140L; REPIN1; ZNF768; NEUROD1; RORA; HMGA1; CREB3L2; NLK; FOXJ2; MYT1L; FOXF1; TAF5L; NFKB2; CBFA2T3; CITED2; YEATS2; ZNF586; SSX1; RBL2; CIZ1; MAML1; BRD4; ZNF652; PBX1; MBD4; ELF5; KLF9; ZNF224; JUP; NR0B2; IRF1; IRF6; CHD3; PDLIM1; ARID5B; PEG3; FOXC1; NFE2L2; SP100; FOXK2; POU4F1; NR2F1; TOX3; MEIS2; INSM1; TCEA2; IRF4; MED23; CNOT6; ZNF160; NKX2-2; PRRX1; PNRC1; RAD21; ASCL1; ZBTB16; JUNB; FOXF2; NR4A2; ITGB3BP; TGFB1; TLE2; NFAT5; ZFP36L2; SMARCA1; STAT1; MNDA; BCLAF1; ZIC1; ZNF611; NFE2L3; MYCL; AES; TRIM22; CREBL2; POU2AF1; CREB1; HLF; RB1; ZNF331; DLX5; NRIP1; TXNIP; ERBB4; ID4; SOX9; FLNA; HOXB2; MYBL1; ZFPM2
Down-regulation	145	FOS; CTBP2; ZBTB18; ASH2L; ING3; HOXD10; TCF12; WHSC1; MXI1; HSBP1; RFC1; TAF10; CCNT1; KLF6; EGR3; ZNF432; CTNNB1; SIRT2; HAND1; ZNF175; RNF4; EYA1; PUF60; GTF2IRD1; UBE3A; TCF7L2; BBX; RBBP4; TAF1A; TAF1D; CNOT1; TBL1XR1; PSMD9; RNF14; LMCD1; AGO2; KAT5; RNF10; MAFB; ELK3; ZMYND8; ZBED2; ZNF532; BCL10; VEZF1; MLX; CARM1; RBM39; BRF2; TRIP6; USP22; PMF1; COPS5; ZNF165; NCOR2; PRKDC; YWHAB; RUVBL2; APEX1; TCEA1; MED13; RCOR1; MXD4; ZNF189; TRIM16; BCL6; ZBTB11; AIP; TP53; CCDC59; ETS2; CBX5; HOXB7; RBPJ; MAF; TFCP2L1; PEX2; ZNF266; ATF3; CITED1; NFKBIA; ATF1; TSC22D2; HOXA11; DACH1; HOXD1; PATZ1; CHD1; MEOX2; ZNF143; SMAD7; ORC2; TLE1; ANKRD1; MAFG; RYBP; PCGF2; EGR2; RCOR3; EHF; PBRM1; RARA; ZSCAN18; ZNF131; TBX3; C1D; BAZ2B; CRK; NR0B1; ERG; MAGED1; SREBF1; MTA1; IFI16; TSC22D1; MNT; BCL11A; TEAD1; HMGB3; RFX5; PIAS2; NR1H2; ZMYM2; BHLHE41; BIRC2; TCFL5; SMAD2; YAF2; ELF1; NEDD8; SMARCA2; VDR; TWIST1; FOSL2; HOXC6; HOXC10; ERBB2; SATB1; HEY1; KDM5D; HOXB6; IRX5; ID1; SCAND1; ABL1