Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76611	Celastrol	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	324	IKZF1; TRPS1; GATA3; ZNF701; ID2; STAT5B; KDM5A; ZNF623; ZBTB20; NFKB2; ZBTB6; WWP1; SOHLH2; FOXG1; PCGF3; GATA6; PAWR; ZNF695; NR6A1; ZNF571; KDM4C; TCF25; CREM; GRHL2; KDM5C; SATB2; MEF2C; HOXC11; ZMIZ1; RARG; ZNF835; NEUROD1; MAF; NKX2-2; SSBP2; KDM4A; CHD2; ERBB4; OVOL2; ELF3; DMTF1; ADRB2; ERF; ZXDC; SCAI; ZNF682; ZNF671; CAMTA1; ZNF217; ZNF148; FOXF1; NR1H4; ZNF329; ZNF214; STAT4; RORA; ZNF157; HLF; LIMD1; HNF4G; SHOX; ZSCAN31; ZNF674; ZSCAN32; ZNF234; CARF; NR5A2; TCF7; ZNF442; ZNF254; SP140; ZNF124; ZBTB38; ZBTB3; SOX3; ZNF253; SUPT5H; ZNF770; SSX7; TOX; ZNF184; ZNF331; ZNF225; DBP; CIC; ZNF44; NR1I3; NHLH1; ZNF80; CAMTA2; PAX4; TRIM24; CERS4; NR3C2; ZNF446; NR5A1; ZNF613; SOX18; TULP4; SOX5; MYT1L; CBX4; STAT5A; ZNF391; TXNIP; PBXIP1; POU1F1; CBFA2T3; GFI1; IRF4; CNOT3; ZNF443; STAT2; ZNF14; VHL; ZNF493; ZKSCAN4; ZNF816; ZNF500; THAP10; E2F2; DNAJC1; SALL1; PITX2; NFAT5; CSDC2; HMGXB3; RELB; ZNF506; TFAP2C; PKNOX1; ZNF536; TAF9B; HOXD3; BRDT; DNMT3B; RBBP5; PHIP; ZNF141; ZNF227; MNDA; ZNF239; ZFP64; ZNF175; TGIF1; ZNF362; ELF5; ZNF257; RBL1; ZNF117; GTF3A; IKZF3; ZNF286A; PHF20; ZNF721; HMGB2; E2F5; LZTS1; CBX8; ATOH1; SPIB; DAXX; ZNF512B; BRCA2; ZNF264; AFF2; BPTF; PHOX2B; ZNF345; ZKSCAN3; SRY; BATF; ZNF492; ZNF557; JUND; PDLIM1; RBPMS; ZNF93; HINFP; NANOG; ZNF136; YBX2; TAF6; SMARCA1; TEAD4; ZNF430; IRF7; CENPB; PRDM10; ZNF160; OLIG2; TRIP11; ARID4A; IL16; ZNF224; HHEX; ZNF107; DCC; ZNF180; PHF1; FOXJ2; ZNF573; ZNF813; ETV5; LHX2; RING1; ZNF165; E2F8; FOXL2; ZNF665; CHD4; BANP; EPAS1; PAX6; ZNF74; EGR4; MYCN; KLF10; UBTF; ZMYND8; NPM1; MTA1; HMGA1; PSPC1; TBL1X; SOX11; CALCOCO1; NFYA; CNOT2; NFATC1; WNT4; ZFPM2; KDM5D; SP3; FOXM1; ZHX2; ZNF85; MXD4; ZZZ3; ZSCAN9; NKX2-1; ZNF112; MEN1; EHMT2; CTNNB1; KAT2B; IRF3; NR0B1; ZKSCAN7; ZNF562; MYBL1; ARID5B; FOXE1; URI1; FOXJ3; GTF2I; AEBP1; HOXD1; TAF1; MYT1; FOXN3; PROX1; JUP; TGIF2; VGLL1; IRF9; SOX10; TERF1; IRX5; CBX3; PRDM2; CERS6; ZNF415; ELF1; TBPL1; ZNF43; WWTR1; ZNF611; ACTL6A; CREB3L2; KLF9; ZNF91; ZNF304; NR4A3; WT1; ZNF200; TRIM16; HMGN3; RUNX1; PLAGL1; NR4A2; BRD2; RXRA; STAT3; NCOA1; ABL1; TGFB1; NRIP1; CITED2; BCL3; ATF5; NFE2L2; NR2F6; BHLHE41; ZNF226; TRIM22; HEY2; BTG1; DLX5; POU2AF1; NFE2L3; AHR; NR1H2; STAT1; SMARCA2; ST18; NR1D2; HOXC10; ING2; SAP18; ZMYM2; JUN; BASP1; OSR2
Down-regulation	413	CCNC; HDAC6; TCERG1; PSMD9; MDFI; SIX2; FOSL1; C1QBP; MBD2; CRK; SOX15; CEBPZ; CSDE1; IKBKAP; NFKBIA; STAT6; FOXP3; ZBTB7A; MLXIPL; CEBPG; UBE2I; HMGB3; PCGF2; ARID4B; ATF2; TFEB; KAT8; ATF6; HCFC1; FOS; RLF; BRD4; MLX; SSRP1; TULP3; MTF1; YBX3; CRY1; ZBED4; MED25; POLR3F; ZNF771; ASH2L; EED; MED21; CLOCK; ADNP2; GABPA; BRF2; HOXB3; EP400; KLF7; C1D; NELFB; ZNF205; GTF2A1; TCF7L1; PPRC1; CHD9; L3MBTL1; PAX8; MYBBP1A; HDAC3; KMT5A; YWHAB; IFI16; MED13; KAT6A; ECD; MMS19; PLAGL2; TBP; PRKDC; IRX4; GTF2IRD1; TAF7; VSX1; MED17; MED24; ZNF692; PBX3; ZNF432; HDAC9; SREBF2; CCDC59; SREBF1; MAZ; USP22; GLI3; RAN; RNF138; FOSB; MEF2A; KDM5B; TAF10; ETS1; PITX3; ZNF140; SIX1; SPI1; MYCBP; SMARCC2; NFIX; ATF3; KLF13; ATF6B; KLF6; MYBL2; VEZF1; FOXN2; ZBTB11; YY1; PSMC3IP; TP63; EMX2; NSD1; BTAF1; USP21; CDX4; RAX; TRAK1; FOXA1; SMAD7; MECP2; HOXB6; NFIL3; ITGB3BP; SUB1; TOB1; SF1; MED20; MTF2; TFAM; HOXA6; SRF; SUZ12; LOXL2; NCOR1; KLF1; TRIM29; ETV4; KAT5; SIX5; SP1; SUPT4H1; ETV1; PAX9; ZNF84; VPS72; HOXB2; ZNF143; ATN1; KLF15; MEOX1; NKX3-1; SMAD3; NCOR2; PAXBP1; BAZ1B; TSG101; KMT2B; HSF2; ZNF12; HOXA7; HES1; SIM2; MZF1; PNRC1; FOXO3; RBPJL; GBX2; BCL6; SPDEF; NR2F2; DEK; CCNH; THRAP3; ZNF783; SMARCA5; ZNF281; TAF11; CBX6; RFC1; ZNF282; CRYM; UTF1; ZNF131; HTATIP2; SIRT7; ATF1; CEBPA; ZNF32; CREBZF; PTTG1; SMAD4; NFIC; HOXB7; NFKBIB; ZNF614; PHF8; TRIM27; GCFC2; ZNF646; ZBTB43; PATZ1; TAL1; HDAC1; MED1; NKX2-5; BRD8; SNAI2; SMARCD3; SMARCA4; HOXB1; VGLL4; THRA; CHD7; MSX1; ZNF276; LHX5; SMARCD2; SMAD1; NCOA3; RNF10; TCF3; LEF1; HOXD10; SHOX2; RFX5; PBX1; HDAC2; TBX10; PITX1; CUX1; SUPT7L; PSIP1; TSC22D2; MAFG; VDR; SPEN; CIR1; MAFF; HEY1; TLE2; DR1; RELA; PIAS3; ZNF787; PHF2; RCOR3; THAP11; TFCP2; POU5F1B; TAF4; EZH2; CREG1; DDX54; HBP1; POU2F2; ID3; MECOM; AGO2; UIMC1; TRIM33; SUV39H1; ZBTB16; PPP1R13L; RERE; NEDD8; CREB3; TOX3; SMARCD1; CENPF; PFDN5; ELK1; TFCP2L1; DDIT3; PMF1; HOXA11; MED15; ZNF8; NFYB; CEBPB; WDR77; GMEB2; MLLT10; LHX1; UBE2L3; REXO4; FHL2; ZFHX3; ZNF274; ZNF593; USF2; E2F3; DEAF1; RRN3; YAF2; IRF8; HOXB5; ZBTB39; NR2C1; HIPK2; KAT2A; SOX13; HIC2; PCGF1; CREB5; TRIP6; MED27; LITAF; SAP30; WHSC1; SETD2; MITF; TFE3; FUBP1; HOXB13; KAT7; RBBP8; RSF1; ZFX; BRD7; TFAP2A; IRF2; CCNA2; MEOX2; NUP62; ELK3; CTBP2; CHD8; BIRC2; PTRF; HIPK3; TTF2; PA2G4; MNT; MNAT1; ZFHX4; NFIB; EGR1; ZNF516; KDM2A; TBX3; XRCC6; RYBP; RBM14; SIN3B; DPF2; KLF4; RFX7; FLNA; FOXO1; SIX3; KAT6B; PBRM1; HOXB9; ZNF337; LYL1; TLE1; RBL2; TLE4; MXD1; ZFP36L2; ERBB2; TCEA1; HLTF; JUNB; ZBTB18; CIZ1; PREB; RHOA; YEATS4; AIP; SSBP3; IRF1; CCNE1; NR0B2; MTDH; NFATC4; TCF7L2; HNRNPD; RBPJ; ZNF423; NPAS2; ZNF654; SIAH2; DACH1; BAZ1A; ZBED2; NFE2L1; SMARCE1; HOXC6; ZNF589; ID1; PIAS2; TCEB2; CBFB; CITED1; AES; CREB1; NR2F1; SALL2; MLXIP; BATF3; MAFB; MEIS2; ASCL1; KLF2; SERTAD2; TCFL5; FOXC1; TFDP1