Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76602	Chir-99021	GSE92742	MCF10A	Human	6h	10uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	ZMIZ1; HES1; LOXL2; TCF3; ESR1; PSMC3; FOXF2; ST18; PCGF3; NKX2-2; MNDA; SRF; CBFA2T3; HOXD11; ZXDC; TCF7; ZNF74; ZIC1; ZNF12; HHEX; COPS2; ZFHX3; NOC2L; ZNF281; TFAP2C; HLX; NR5A2; EMX2; ZEB1; HOXD1; ELF4; EGR2; CENPB; SHOX2; PAWR; EN1; ARNT2; KAT2B; BHLHE41; TCF7L2; ZSCAN31; NFE2L2; HOXB2; POU4F1; HOXB7; HOXB13; NR4A2; MTA1; LEF1; MYRF; PEG3; AR; DLX5; NHLH2; AHR; IRF1; CUX2; ATF3; ILF2; KLF10; SOX17; HOXB6; TCEA1; ZNF232; FOXF1; PAX5; NR4A3; KLF13; ETS2; IRF9; TOX3; ZFPM2; KLF4; CALR; PAX6; PHIP; JUN; ZFP36L2; HIC2; NRIP1; STAT1; ZNF331; ARID5B; TGFB1; ID3; ATF5; ZFP36L1; CREB1; MYBL1; NR1H2; BASP1; ZNF91; POU2AF1
Down-regulation	91	MYC; SIX2; UBE2B; ETV1; ELK1; YBX2; DNMT3B; ZNF580; UBE2I; ADRB2; NFIL3; TAF10; NELFB; MXI1; GATAD2A; ZMIZ2; SIX1; LZTS1; ZNF24; TSC22D3; TRIP6; SLC2A4RG; RBPMS; LITAF; KDM5A; TRIM28; MED14; ZEB2; BRD8; HMGN3; SMARCC1; HMBOX1; BAZ2B; HTATIP2; KAT8; RFX7; EZH2; STAT6; ZMYND8; TFAP2A; GLI3; TFCP2L1; PMF1; JARID2; HIPK3; SMAD5; NRBF2; RFX5; CBX3; CARHSP1; PBX3; MNT; PIAS2; POLR2A; CBX5; YEATS4; SMAD2; ZNF267; TBL1X; ATF1; TP53; CREB5; DNAJC1; PTTG1; NFIB; SIAH2; KLF2; GTF3A; KDM5D; IRX5; TEAD1; LMCD1; FOXC1; SATB1; MITF; DAXX; HOXC6; ELF1; PDLIM1; ATF7IP; WWTR1; SOX9; HOXC10; ZMYM2; ERBB2; ABL1; SPEN; NR1D2; KAT6B; NFATC3; TCFL5