Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76585	Afatinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	ZNF536; ZNF623; TRIM24; NR4A2; THAP10; GATA6; ZNF16; DACH1; MXI1; SSBP2; HAND1; ZEB1; TSC22D3; TCF7L2; WNT4; ST18; BRCA2; ZNF227; HLX; GFI1B; ZXDC; ZBTB43; NFIL3; PITX2; MED12; NHLH2; RING1; HOXD1; ZSCAN31; ZNF264; ZNF551; MYT1; TAF5L; INSM1; NFKB2; ZNF345; SOX11; ARID5B; GRHL2; NEUROD1; ACTL6B; OSR2; HMG20A; PAX6; ZNF148; PROX1; ZNF180; KLF11; PNRC1; TCF7L1; NCOA2; NKX2-1; URI1; ZNF124; RAD21; CSDC2; FUBP1; ZBED1; ZFPM2; CHD4; MYRF; TBX3; ZNF12; E2F8; ZNF331; EN1; FOXE1; TOX3; NFE2L2; INSR; LMCD1; KLF13; TLE2; PBX3; ZNF33B; WT1; BRD4; ELF5; NR2F1; NFE2L1; ZNF22; ZIC1; CREM; PSMC3; MEIS2; ENY2; CD3D; IRF9; STAT1; ZNF423; NR4A1; NR2F2; IRF6; ZNF117; ATF3; IRF7; MEIS1; FOXN3; CITED2; AES; ZBTB16; TXNIP; DAXX; JUN; MYBL1; TLE1; NR1D2; HIRA; ZNF131; TRIM22; PSIP1; RB1; HIC2; FOSL2
Down-regulation	113	FOSL1; MYC; LITAF; HIVEP2; TRIP6; TSC22D2; FOXG1; ZNF671; STAT6; TFEB; POU5F1B; FOSB; BCL10; TAF10; ELK3; ADRB2; HES1; MYCBP; SOX15; EGR1; YWHAB; PA2G4; UBE2I; ZNF528; RBPMS; ING3; MLX; TSC22D4; NUP62; SF1; E2F3; NFIX; NPAT; THAP11; NKX3-1; TCERG1; CEBPZ; ESR1; EMX2; SMAD3; ZNF83; TFE3; PPRC1; GATAD2A; DDX5; NANOG; RERE; GLI3; EGR3; NRIP1; KDM5D; ASH2L; CALR; CTNNB1; LPIN2; PDLIM1; SOX9; BTAF1; HDAC9; ZNF432; RBM14; CCDC59; SMARCA4; MSX1; NFATC1; GABPB1; REST; MAFF; FOXO1; TFAP2A; ZNF143; LIN28A; SATB2; BCL11B; NPAS2; CBFB; TAF1D; CHD3; SMAD7; RFX5; NEDD8; ZNF165; VDR; ORC2; ZFP36L1; SOX17; ZSCAN18; BAZ1A; BHLHE41; MAFG; MEOX1; MNT; CRY1; IRF8; ZMYND8; SATB1; NR0B1; ZBED2; KAT6B; XBP1; CARM1; CRK; PITX1; KLF2; JARID2; TP53; MAFB; HOXA10; FOXF1; HOXA5; RBBP8; ZNF589; SCAND1