Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76583	Afatinib	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	166	L3MBTL1; TRPS1; ZNF623; E2F8; ST18; ESR1; CERS4; TFAP2C; ZSCAN31; NEUROD1; DMTF1; TULP3; ZNF557; NR2F1; ZNF350; POU1F1; MED14; ZNF141; ZNF157; ZNF770; TDRD3; ZNF695; SIM1; ZNF107; ZNF175; CARF; EMX2; FOXA1; ZFPM2; ZNF135; PBX1; ZNF205; FOXG1; SALL1; ZNF248; AR; ZFX; NAB2; NR3C2; TBX1; SSBP2; PFDN5; ZNF646; ZNF682; AFF2; BRDT; ZNF536; CREM; TCF21; TBX3; FOXL2; ZNF329; AEBP1; ERBB4; TFEC; FOXE1; SOX12; ATF2; ZBTB16; ZNF551; E4F1; NANOG; ZNF345; ZEB1; LIN28A; NR5A2; TERF1; ZNF34; ZNF250; TEAD3; OSR2; NKX2-1; SOX3; MEIS2; SPIB; BLZF1; FOXF2; CIR1; NR0B1; TGFB1I1; ZNF606; ZNF74; BHLHE41; TTF2; BNC2; CEBPD; PNRC1; PEG3; GATA6; SCAI; ZNF768; JUP; MECOM; TOX; TCEB2; TSC22D3; PGR; CEBPA; ZNF667; NR4A2; STAT1; NR2C1; WT1; ATF3; CREBL2; INSM1; ZNF33B; PKNOX2; GTF2F1; ZIC3; COPS2; ZNF331; MYBL1; EYA2; HOXB6; THAP10; REL; HEY1; LZTR1; SALL2; TFAP2A; ID4; CD3D; PRRX1; POU4F1; KLF9; SOX17; HOXA4; JUN; ARNT2; ZNF112; TCEA2; FLI1; ZHX2; ZBED2; TCF7L2; EGR2; SNAI2; MNDA; PRDM2; RB1; MYCL; CITED2; CALCOCO1; MAF; ZNF117; RAD21; PHIP; SUPT3H; FOXF1; IRF9; NFE2L3; SMARCC2; TCEA1; HOXB5; TLE2; ZSCAN18; ZKSCAN1; CREB1; FOXN3; SSBP3; IRF6; TCF4; ARID5B; KAT6B; POU2AF1
Down-regulation	251	FOSL1; MYC; TSC22D2; NELFB; TRIP6; ELK3; ERF; VPS72; GTF2IRD1; ZNF408; CTR9; TAF10; IKBKAP; EYA1; BCL10; CENPF; HIPK3; HLTF; CCNT1; CBX3; NFRKB; ZNF783; REXO4; CHD1; MED27; RELA; RNF4; CIC; RBM14; BASP1; TCERG1; RNF141; GATAD2A; UIMC1; GON4L; MYCBP; ADNP; FHL2; ZNF146; TRIM32; TFEB; BAZ1A; CRK; CAPN15; PML; HNRNPD; ZNF672; ARID3B; ZBTB7A; SP2; KDM5D; EWSR1; ADRB2; NKX3-1; NUP62; SETDB1; SETD2; AFF4; TSG101; SIRT7; SIX2; NSD1; PHOX2A; TTF1; HIF1A; PHF2; RERE; ZBTB18; KLF7; RNF138; ETS2; CBFB; ZNF222; KMT2B; PARP1; YAP1; ZNF24; SMAD1; KLF3; PPP1R13L; CRY1; MTF2; GATA3; CHD9; SMARCA4; ZFHX4; TRIM25; PHF20; NPAT; ZBTB38; MAFG; SOX4; CEBPB; CARHSP1; SUV39H1; NFIB; TRIM33; CHD7; BRD3; MTF1; NRBF2; TAF1D; FOXO3; TERF2; CARM1; RNF14; VEZF1; SMARCA5; CEBPZ; PPARG; JARID2; MNT; NFATC1; ZNF282; NR3C1; ZMYND8; RUNX1; HMGB3; RBPJ; ETV4; KDM5B; DEAF1; SOX9; ZEB2; SFMBT1; NFKB1; SPEN; ZNF45; ZNF143; PREB; ABL1; RNF111; ZBTB11; ARID4B; HIVEP2; LITAF; GABPA; BRPF1; SNIP1; ZBTB40; XBP1; ELF4; FOXK2; NFIL3; ZNF131; TLE1; LIMD1; TRRAP; YWHAB; RBBP4; SREBF1; TBP; PTRF; ZFP36L2; NCOA4; EGR1; TP53; NR2F2; USF2; PATZ1; ZZZ3; RNF6; SIN3B; NR1H3; CCNE1; ARNTL; PAXBP1; SMAD5; HDGF; BCL11B; NR1H2; RHOA; FOXD1; HOXC6; MED1; PIAS2; IRF2; SMAD3; CXXC1; CSDE1; PDLIM1; BTAF1; RYBP; DPF2; JUNB; GMEB2; CAMTA1; TGFB1; E2F3; BIRC2; HMBOX1; TFAM; REST; SMAD7; SERTAD2; CREB5; ZNF629; CDK9; PIAS3; NCOR2; KDM2A; BMI1; ECD; KLF2; ZMYM2; USP22; SOX11; BCLAF1; SMARCE1; BCL3; CTBP1; NFKBIA; BRD8; FOXJ3; ELF1; DR1; MSX1; ERBB2; RFX7; MXD1; HOXA10; C1D; EGR3; YAF2; TBL1X; NCOA6; MED24; SIX1; SCAND1; PTTG1; PSPC1; HSF2; ENO1; VGLL4; SMAD2; ID1; DAXX; MTA1; ATF4; HTATIP2; HOXC10; SUB1; SIAH2; FLNA; ATF1; TOX3; ZNF226; TRIM29; ID3; FOXO1; FOXC1