Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76581	Azd-5438	GSE92742	MCF10A	Human	6h	0.08uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	132	GATA3; TRPS1; FOXG1; HINFP; ZNF623; CNBP; ST18; HAND1; TCF7; SMAD3; GATA6; MECOM; KLF9; IRF6; HIRA; CDX1; ZNF22; ZNF74; RNF138; ZNF141; NEUROD1; HOXD1; ZNF536; ERBB4; FOXF1; EYA1; PRMT2; ZNF33B; ARID5B; TDP2; TBX21; PEX14; ZNF721; PNRC1; WWP1; MNDA; PHOX2B; THRA; THAP10; ZFPM2; CAMTA1; TCF7L1; ZNF133; KLF3; RBM39; ZNF611; ZNF816; FOXF2; ZSCAN31; KAT2B; ZIC3; THAP7; ESR1; KLF13; ACTL6B; DLX2; PAX6; NFATC4; ZNF232; AHR; MXI1; EMX2; ZNF160; NR4A2; CRYM; GRHL2; RORA; PFDN5; AR; NFE2; ZNF124; ATF3; HOXB5; NFE2L3; RAD21; PRDM1; HOXB2; ZNF331; ZNF423; TOX3; NR0B2; E2F8; ZNF652; CHD4; JUP; MEIS2; INSM1; MAF; PIR; CUX2; ZNF136; CD3D; SUPT3H; ISL1; CREBL2; MYCL; SOX2; SOX17; ZNF264; ID4; RB1; TBX3; NR2F6; NFKB2; ZFP36L2; TGFB1I1; NFE2L2; OSR2; IRF9; MEOX2; ILF2; CCNE1; FOXD1; PRRX1; HDAC9; ZNF467; JUN; CREB1; BNC2; VGLL4; IRF7; NR2F1; ZIC1; KLF5; HOXB6; FOXJ3; IRF8; TCF21; MYBL1; BTG1; MEIS1; ZNF91
Down-regulation	207	FOS; NFKBIA; TSC22D2; CTR9; ZNF107; SAFB2; FOSB; ASH2L; DDX5; CHD9; TAF10; ELK1; BRD8; PPP1R13L; ETV1; EZH2; CCNA2; HDAC6; STAT6; NELFB; UIMC1; DNAJC2; RUNX1; CCNC; BAZ1B; NFIB; TSC22D3; PSMD9; NCOR2; HCFC1; RBBP5; CENPF; SMARCA4; RBPMS; NFYB; TFE3; UBE2B; DNMT3B; MED20; BRF2; NFIL3; FOXO4; ZNF783; ERCC2; RBM14; SND1; POLR2A; TRIP6; PTTG1; RNF10; CEBPA; PURA; TAF1A; UBE2I; HTATIP2; TDRD3; NUP62; ELK3; FHL2; HES1; CNOT1; MBD2; CRK; NKX3-1; ARID4B; LITAF; PRKDC; ZBTB24; DDX54; YWHAB; MITF; EP400; SIM2; MED6; E2F3; BTAF1; WWC1; TCERG1; BAZ1A; PITX1; JARID2; PPARG; SETD2; BASP1; REST; ZBED2; NRBF2; HMBOX1; MTF2; NFIC; GATAD2A; RBBP4; BRPF1; CBFB; AFF1; NPAS2; JUND; FOXO3; SIN3B; HOXC6; RNF4; TBL1XR1; TCF15; RNF141; PHF8; KLF2; ECD; MAFG; TRIM28; CARHSP1; SMARCA5; IKBKAP; HMG20A; SMAD1; TRIM16; ZMYND8; HDAC1; LPIN2; ZNF23; KAT7; PA2G4; RFX5; ELF1; RNF14; SIX1; SIX2; AATF; KMT2B; TSC22D4; KLF6; SMARCA2; CARM1; SUV39H1; RUVBL2; TRIM29; USF2; LOXL2; CRY1; TBP; NCOA4; BATF3; PMF1; CCDC59; ZNF267; KAT5; BCL11B; ZBTB11; RNF6; TRRAP; BIRC2; DPF2; PLAGL1; BAZ2B; VEZF1; IL16; IFI16; CHD7; TP53; NR0B1; SMARCD3; ZNF410; TBL1X; PDLIM1; HOXA11; XBP1; NFATC3; DNAJC1; ZMYM2; USP22; TLE4; TMF1; MLXIP; HLTF; ZBTB38; FOXC1; VDR; MED1; ORC2; SATB1; SMARCE1; HMGN3; FOXO1; PREB; SPEN; FOSL2; NEDD8; ERBB2; RFX7; PIAS2; MNAT1; MEOX1; HOXC10; PAX5; ING2; GABPB1; ID1; ID3; SIAH2; TCFL5; TOB1; SOX11; KDM5D; BHLHE41; ATF1; MSX1; ABL1; KAT6B