Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76580	Azd-5438	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	ATOH1; PSMC3; TFAP2C; KLF9; FOXA2; ZNF3; FOXJ1; TERF2; HOXD1; RNF138; INSM1; MYRF; ZNF195; SNAI2; NR5A2; TRPS1; ZNF721; SOX10; ZFHX3; ILF2; KLF13; IL16; PEG3; EMX2; TCF21; TDP2; COPS2; BHLHE41; TULP4; HIPK2; SOX2; ATF3; UBE2L3; MAF; MDM2; SMAD7; ZNF12; PDLIM1; ZEB1; NFATC4; CREB3L2; ZNF544; ZNF160; THRA; NEUROD1; ID4; ZIC1; IRF9; POU4F1; SMAD1; FOXF2; DEK; MNDA; ZNF136; FOXF1; PRRX1; BNC2; EHF; TXNIP; HMGA1; HEY1; CERS6; ZBTB16; SSX1; KLF10; SMARCB1; TBX3; PFDN5; HMGA2; ZSCAN18; SOX17; RBPJ; LMCD1; PBX1; ELF5; EGR2; ZNF331; CREBL2; LEF1; ZKSCAN1; PEX2; BCL11A; GATA6; AEBP1; JUN; ABL1; ZNF652; TOX3; STAT1; ZNF589; ZNF91; NRIP1; ZFPM2; CREB1; WT1; SALL2; MED1; NR2F1; SOX11; ARID5B; HOXB2
Down-regulation	166	TRIB3; IKBKAP; SOX12; BRD8; CIC; RBBP5; CTR9; TRIP6; BPTF; NELFB; LPIN2; NKX3-1; SAFB2; TCF3; UBE2I; BLM; AFF1; ZSCAN32; TTF1; ZBTB11; BRD3; CENPF; ERF; TRIM32; CARHSP1; DDX5; UBE2B; ZNF45; HDAC3; SETD2; RBPMS; RCOR1; GTF2IRD1; ZNF468; NFIB; TBPL1; SMARCD1; PPP1R13L; ELF2; RFX5; NFIL3; SMAD3; PHF2; MAZ; HOXC6; ZBTB43; TLE4; NRBF2; MAML1; HOXC10; NFKBIA; HMG20B; DNMT3B; CIZ1; ZNF184; JARID2; TRIM28; EGR1; ARID4A; CBX3; ADRB2; BAZ2B; BCL6; ZNF200; PSPC1; CEBPB; HTATIP2; RBBP4; MXI1; ZNF189; MYCN; STAT6; ING1; POLR2A; MNT; GATAD2A; ZNF217; RNF111; RNF10; CDK9; RFX7; CHD9; REST; SIX1; CTBP2; PATZ1; SMAD5; ATF7IP; ZMYND8; DNAJC1; PNRC1; PPARG; PITX1; BCOR; RNF4; HMG20A; RXRA; PMF1; BMI1; SMARCA5; ARID4B; HMGN3; TBL1X; CITED2; SLC2A4RG; IRX5; TAF10; TGIF1; HLTF; GABPB1; JUNB; BAZ1A; HNRNPD; CHD3; TGFB1; TBL1XR1; ZBTB18; ELF1; ZNF532; YWHAB; BCL3; MAFB; FOSL2; ATF1; SREBF1; ZNF131; FOXC1; ATF5; TMF1; TRIM16; CRY1; NCOR2; HSF2; TEAD1; SPEN; GTF3A; NCOA6; ELK3; FLNA; ORC2; HOXA1; KLF2; CARM1; VEZF1; PIAS3; CCNA2; YAF2; NR2F2; NR1H2; NFATC3; PIAS2; MTF2; ZMYM2; ATF4; TSC22D3; ELF3; FOXJ3; TFCP2; ZBTB38; ZNF226; BTG1; MSX1; TOB1; SOX9; BASP1; TCFL5