Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76579	Azd-5438	GSE92742	MCF10A	Human	6h	10uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	214	GATA3; TRPS1; NAB2; PCGF3; SOX2; SIX6; ESR1; MNDA; AR; ZIC3; ERBB4; ZMIZ1; ZNF273; HES1; MED12; TEAD3; NEUROD1; CBX4; KDM5C; ZEB1; NR4A2; ZFPM2; NR2F1; E4F1; ATF3; TFAP2C; CEBPE; MEIS2; GATA6; EMX1; TCF7L2; STAT5A; INSM1; SHOX2; CSDC2; TBX3; SMARCA1; ST18; ELK4; ZNF219; WNT4; RING1; ZBED1; CERS4; ZNF350; NHLH1; HDAC6; SMAD3; MYT1; SOHLH2; CBFA2T3; ZNF264; CAMTA1; ZNF701; NFKB2; LIN28A; HDAC5; ZNF141; NEUROG1; HSF1; ZBTB17; HMX1; PRRX1; ZNF623; ZNF91; MED14; ZNF74; SP140L; NR2C1; FOXF2; TFDP2; ARID3A; ZXDC; NR5A2; TAF6L; ARID5B; THRA; KLF13; INSR; ZSCAN31; RORA; GRHL2; PIAS4; PAX6; LHX2; CHD2; JAK2; TCF7L1; FOXF1; HBP1; KLF11; IRF1; TFAP2A; PGR; HDAC4; CDC5L; IRF6; DLX2; NFE2L2; TAF1C; ACTL6B; TERF1; BHLHE41; SNAI1; ZNF816; MECOM; HOXD3; HIRA; HOXD1; ZNF394; ZNF44; ETS1; COPS2; REL; ZNF331; SSBP3; THAP10; AFF2; E2F8; ZNF136; SOX3; CAMTA2; ZNF544; NR4A1; ZNF512B; ZNF75D; TLE2; CALCOCO1; DLX5; PFDN5; SREBF2; ZNF93; OVOL2; PRDM2; NR0B2; ZNF268; NR4A3; PSMC3; CD3D; EMX2; ING4; ZNF117; ID4; SPDEF; ARNT2; ZNF22; NR2F6; DACH1; CDK2; BARX1; ELF4; CUX2; ZNF195; KLF9; FOXM1; ZIC1; TGFB1I1; MYCL; SOX17; ESRRG; SMARCD3; MYRF; CDIP1; OSR2; NFE2L3; ZNF239; SALL1; FOXA2; SALL2; CREM; PHIP; IRF9; JUN; BRD4; SSX1; ZNF430; POLR3C; ZNF12; ZNF423; EGR3; TAL1; NHLH2; TRIM22; TCEA2; SSBP2; MTA1; HOXB5; WT1; RBBP8; MAF; JUP; VPS72; ZFP36L1; ZNF665; NCOA1; ZNF43; PEG3; RB1; HHEX; CITED2; AEBP1; TCF21; PBXIP1; TOX3; ELF5; NR1H2; EYA2; MYB; FOXN3; DAXX; HIC2; MLXIP; FOSL2; TCF4
Down-regulation	295	PARP1; RBBP4; NFKBIA; CTR9; EZH2; SIX2; E2F5; DNAJC2; TBP; CCNA2; RBBP5; ZNF146; ZBTB24; ELK3; EYA1; LITAF; TSC22D2; BASP1; MLX; UIMC1; TRIP6; ZBTB11; BRD8; CEBPZ; BCL10; CDYL; RBM14; SOX15; MSL3; MYC; CTBP2; PTTG1; EED; RNF141; CRK; SFPQ; ADRB2; HNRNPD; UBE2I; LOXL2; SUZ12; ARL2BP; CCNC; LPIN2; ZNF764; NR2F2; NUP62; MED1; HSF2; SAP30; THRAP3; ZBTB25; MDFI; FHL2; ETS2; TCERG1; ZNF468; BLM; SETD2; HCFC2; CTNNB1; TSC22D3; BAZ1A; PATZ1; ZBTB7A; SMAD5; RNF14; TSC22D1; TRIM32; ZSCAN12; SUV39H1; ADNP; ASH2L; SMARCA5; USP22; NFIL3; VGLL4; ZNF14; ZFHX4; DDX5; ENO1; TAF10; DPF2; UBE2B; SAFB2; ASXL1; PIAS2; GTF2A1; CDK7; GATAD2A; E2F3; TBL1XR1; REST; RYBP; TRIM27; SMARCE1; PSMC3IP; XBP1; EWSR1; ECD; RFX7; SNW1; CLOCK; KDM2A; TAF1D; PURA; ELK1; PIAS3; HIPK3; PMF1; ELF2; BAZ1B; WDHD1; RUVBL2; SIX1; MTF2; MAGED1; ZMIZ2; TLE4; BMI1; MED6; BCOR; BRCA1; MTDH; TLE1; RFX5; PCBD1; LYL1; CENPF; TGIF2; FOXO3; RUNX1; SFMBT1; RHOA; GABPA; HDAC1; TFAM; HTATIP2; CBFB; YAF2; E2F6; ZNF672; CEBPG; ZNF131; ING3; ZNF384; CARM1; HMG20B; ZNF614; RUNX3; CHD1; ZNF302; FOXJ3; CRYM; TFEC; HMBOX1; USF2; BIRC2; ATF4; ZBTB38; TAF9B; ZBED4; NEDD8; AFF4; KAT7; DDX17; KDM5B; TBPL1; AATF; CHD9; FOXO1; PSMD9; MED7; PCGF2; VDR; BRPF1; ARID4B; TSC22D4; CBX3; RFC1; MAZ; RNF4; ARNTL; SCAND1; ZMYND11; BCL11B; ZNF432; ERF; CEBPB; ALX1; HOXC6; SOX11; SMAD1; ZNF23; ZNF266; EGR1; ETV4; PPARG; ZBTB1; ZNF281; RBM39; NFE2L1; SPEN; THAP1; ZNF419; CREBZF; XRCC6; RRN3; VEZF1; BATF3; THAP11; CRY1; KAT8; LIMD1; TXNIP; ZNF267; HOXA10; DR1; AHR; FOXD1; TP53; ZNF473; POLR2A; GABPB1; BATF; NFAT5; YBX1; UBP1; ZNF200; ERBB2; NPM1; TFCP2L1; NRBF2; TEAD1; BRD2; SMARCA4; MED17; HOXA11; MED23; NKX3-1; KLF5; RBPMS; HEY1; HOXC10; RNF6; KLF2; BTG1; PHF20; NCOA6; BRIP1; PIR; ING2; SOX9; SMARCA2; TRIM28; ZBTB18; ORC2; ELF1; TWIST1; RNF10; MAFB; TRRAP; ZNF532; TMF1; TOB1; RCOR1; ZNF143; CCDC59; YWHAB; SATB1; DDIT3; MEOX1; NPAS2; MNAT1; ATF1; HMGN3; IRF4; STAT3; HLTF; ZBED2; ABL1; CDK9; MNT; CCNH; MSX1; CREG1; TRIM29; MYCBP; AFF1; BACH2; ID1; ZNF226; ID3; LEF1; NFATC3