Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76572	Nvp-aew541	GSE92742	MCF10A	Human	6h	2uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	188	IKZF1; TRPS1; TBP; HBP1; GATA6; HES1; HAND1; SSBP2; TCF7L2; TCF7L1; EN1; KLF9; TSHZ2; HAND2; CERS4; ZNF623; MNDA; ST18; HMX1; FOXF1; ATOH1; HSF4; ELK4; TCF7; WWP1; ZNF107; TULP4; ZNF688; PIAS1; TFAP2C; CIR1; NR5A2; SOHLH2; PEX14; PNRC1; NHLH1; NR2F1; THAP10; PROP1; HHEX; LEF1; DLX2; TRIM24; ZNF721; CEBPD; ZEB1; ZNF91; MAF; ZNF701; NKX3-2; CITED2; ZNF93; PAX6; TSC22D3; ZNF536; SHOX2; ZNF415; FOXG1; ZBTB16; PRRX1; FOXN3; IRF6; ZNF253; CBFA2T3; DBP; ATF3; ZNF227; TBX3; MYCN; GRHL2; JUP; TDRD3; RORC; KDM5B; HDAC5; EVX1; LDB1; HEY1; ZSCAN9; FUBP1; CSDC2; FOXE1; ZNF350; ZNF611; ING4; SPDEF; HIPK2; COPS2; KLF13; NR1H3; SOX2; TOX; ERBB4; EZH1; ZNF711; SOX3; ZNF573; TERF1; INSR; PSMC3; GATA1; ZNF665; ZNF160; CDIP1; ZNF34; ZFPM2; SMAD6; TWIST1; PRDM2; FOXF2; INSM1; MAFB; HSF1; ZNF302; CBFA2T2; IRF9; SOX11; PFDN5; MEIS2; VPS72; ZNF85; SUPT3H; ESRRG; ZNF22; CUX2; NR0B2; ZNF239; LOXL2; ZNF250; NFATC4; TCEB2; NEUROD1; ZNF232; ZNF532; E2F8; ZNF33B; HOXA4; ARID4A; TGFB1I1; CD3D; SSX1; MYCL; TOX3; ARNT2; LIN28A; SOX13; ZNF654; ZNF83; TCF21; KLF7; CITED1; THRA; ZNF117; VGLL4; MYBL1; ID4; SNAI2; ZNF268; HIRA; AEBP1; CREBL2; ELF5; PBX3; MYB; PBX1; ZNF467; HOXB6; CCNH; KLF5; ZNF423; HOXB2; ZKSCAN1; ARID5B; TCEA2; ZFP36L1; TXNIP; AHR; ATF5; JUN; SMARCA1; FOXD1; THAP11; ID3; KAT6B; ZSCAN18; SOX9; ASCL1; ZIC1
Down-regulation	217	PSMD9; BTF3; TRIP6; CTR9; FOSL1; TSC22D2; EZH2; CDYL; RBBP4; CCNA2; ABT1; TRIM28; RBBP5; MYCBP; LITAF; CEBPZ; STAT6; SIX2; ELK1; CCDC59; GATAD2A; HIPK3; YWHAB; KAT7; SETD2; DRAP1; NR1I2; PRKDC; SMARCD1; RBM14; SMARCA4; RNF10; NUP62; ETS2; TFEB; TRIM25; BAZ1A; UIMC1; HDAC1; CRK; SMARCA5; TOPORS; TAF9; SAFB2; MYC; MED13; SP2; NKX3-1; ZBTB11; UBTF; SMARCD2; SUPT4H1; MLX; PURA; HDAC2; PBX2; ZFY; ZNF614; CEBPG; VEZF1; EMX2; FOSB; CCNT1; NELFB; PLAGL1; SUV39H1; CRY1; HNRNPD; NFKB1; GABPA; MSX1; DDX54; ZNF672; RNF141; MED1; CHD1; CARM1; TTF1; RHOA; ADRB2; TGIF2; TCERG1; ZBTB24; TAF10; E2F6; YBX1; NCOR1; DNMT3B; RFX7; MDM4; GTF2IRD1; ZBTB38; PMF1; ELK3; KDM5D; ORC2; ZBED4; URI1; KLF10; ERF; E2F5; XBP1; TLE1; REST; RNF14; BAZ1B; BMI1; PATZ1; FOXO3; PSIP1; WHSC1; PTTG1; BCL3; PPRC1; FOXJ3; NFYA; RFX5; TRIM16; CSDE1; KDM5A; NCOA6; ZNF266; ZNF576; LIMD1; CLOCK; CDK8; BIRC2; RNF6; ARID4B; SMARCC2; RCOR1; BRD2; PHF2; PA2G4; TAF1D; BRD8; ABL1; ZNF143; CARHSP1; ECD; POLR2A; MTDH; MAGED1; NRBF2; TP53; ZNF148; ING2; BBX; TFCP2; RBL2; SMARCA2; RUNX1; TEAD1; NEDD8; TRRAP; DR1; ASH2L; ELF3; FOSL2; AATF; ZBTB1; ZNF23; FOXL2; CREB5; PREB; FLNA; TMF1; KLF6; PIR; ID1; MXD1; HOXC10; CBX3; NCOA4; TFCP2L1; SIAH2; ELF1; SATB1; MED24; PIAS2; SMAD7; SCAND1; USP22; CBX5; HOXA11; POU4F1; NCOR2; C1D; JARID2; BASP1; CCNE1; DAXX; HOXA10; AFF1; ZNF512B; HTATIP2; SMAD5; IRF7; MTA1; SATB2; SMAD2; GABPB1; TCFL5; ATF7IP; SIX1; ENO1; HMGA2; HMGN3; ERBB2; ATF1; NR1D2; TLE4; TBL1X; POU2AF1; RUNX3; FOXC1; PITX1