Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76569	Veliparib	GSE92742	MCF10A	Human	6h	0.4uM	EID0440

Response Information :

Types	Number	Response transcription factors
Up-regulation	227	GATA3; TBX2; TRPS1; ZNF623; RORA; PCGF3; BHLHE41; ZNF44; ZXDC; NFKB2; ARNTL2; SALL1; MAF; PLAGL1; CBX4; NAB2; WNT4; ID4; CREB3L2; SMAD6; EN1; HES1; SKIL; NR5A1; RARG; EPAS1; PITX2; E4F1; ELF5; HSF4; SNAI1; SP140; ETV5; THAP10; ZNF696; GATA6; HSF1; SOX18; ZNF14; TCF7L1; GRHL2; HABP4; TBX3; USP16; TEAD3; HIC1; SHOX; YAP1; SOX3; FOXF2; ETV6; MBD1; MEIS2; MECOM; FOXG1; PAWR; HOXA3; ZNF423; FOXJ2; NFE2L3; SOX4; TCF25; ZNF701; ZNF266; NCOA2; E2F8; ZBTB17; FOXC1; HOXA11; IRF9; DYRK1B; WWP1; ZNF16; IRF4; OSR2; NR4A2; HOXD10; PEG3; TCF7; CERS4; SMARCA1; ARID5B; PIR; ZNF331; ZNF250; E2F2; TULP4; MXI1; ZNF148; ADNP; NFATC1; TFDP2; TBX21; ZNF12; TBL1X; DAXX; NCOA1; ERCC3; ENY2; BRCA2; ZNF215; ZNF7; PRMT2; IRF5; TFCP2L1; ERBB4; CREB1; MYBL1; HOXD11; TERF1; PAX6; ZNF587; ZNF235; DLX4; ZNF492; MED14; SHOX2; CSDC2; GCFC2; ZFHX3; CBX7; CCNE1; HOXD3; NR0B1; PRDM2; ZNF195; VGLL1; CAMTA1; POU4F1; FOXF1; MED15; NR2F1; TFAP2C; DLX5; SOX17; NFE2L2; TGFB1I1; HIRA; HOXA10; ID1; WT1; KLF4; SP140L; BARX1; STAT1; KAT2B; ACTL6B; HEY2; ZNF160; RBFOX2; HDAC5; FOXM1; NR4A1; HOXB7; TP63; HDAC4; SMARCD3; KLF10; ZSCAN31; ZNF611; ZNF124; CUX1; ZBED1; ELF3; ZNF33B; NR5A2; SREBF2; SOX10; RBPJ; MED17; KLF7; ZBTB16; SP3; CALCOCO1; LIN28A; PFDN5; PRDM1; KLF13; BCL6; NEUROD1; TCF4; CREBL2; BRD2; KLF6; PNRC1; HOXB5; NR4A3; HOXB6; ZNF721; KLF5; ZBTB1; PLAG1; BCL11A; MYCL; PHIP; WWTR1; FOXL2; ZBTB38; ESR1; EGR2; ZNF131; FOXJ3; ZNF93; ZNF512B; HOXA5; SATB2; ZNF117; ZNF264; TOX; NR2F6; KAT6B; MAGED1; ATF4; BTG1; TRIM22; TCEA2; JUN; HOXB2; SAP18; NR1D2; ING2; ZIC1; RB1; HMGN3; POU2AF1; NFATC3; ZFPM2
Down-regulation	300	PARP1; ARID4B; LITAF; DDX5; JUND; RAN; C1QBP; HDAC6; RHOA; ZNF672; MLX; CCNC; FOXA1; SUZ12; PATZ1; MAZ; UBE2I; VPS72; ASH2L; FOSL1; TCF12; RNF138; MLXIPL; PCGF2; ZNF652; ETV1; ELK1; CTR9; SPDEF; USP21; RBM14; BLM; SOX15; WDR77; CTNNB1; SMAD1; TSC22D2; CRY1; RBBP5; BRD8; FOXO3; TBP; BAZ1A; MED1; NELFB; KDM5B; ZMYND11; TFEB; SREBF1; CSDE1; REST; ZBTB11; USP22; CALR; MTF2; DEK; PHF8; TAF10; MED20; ELK3; ZNF24; NKX3-1; SETDB1; SMARCA5; SFPQ; ZBTB18; ZNF32; MYCBP; SFMBT1; PMF1; MDM4; SMARCD1; AATF; NFYB; SP1; BRCA1; HMGB3; ZNF212; BAZ2B; PCBD1; BMI1; HIPK3; POLR3F; SAFB2; EWSR1; PHF2; ZNF692; STAT6; SMARCA4; SP2; ZNF146; ECD; HSBP1; DRAP1; FUBP1; PRKDC; CCDC59; ADRB2; CLOCK; MDFI; ACTL6A; ELF2; PMS1; TRIP4; RBPMS; CENPB; SNW1; TADA3; SETD2; ZBTB7A; TERF2; VEZF1; PTTG1; RFX7; HNRNPD; MTA1; ZNF764; RBBP4; SMARCE1; SMAD3; GTF2A1; THRAP3; THAP11; MEOX2; WWC1; PSMD9; ZNF140; ZNF337; HIVEP2; RUVBL2; ZNF302; PREB; ING3; KAT7; DR1; NFKBIB; VDR; TCERG1; SUV39H1; FOXN2; EGR1; TSC22D4; RNF111; ZNF8; REPIN1; HMG20A; E2F6; EZH2; CTBP2; TLE1; TFAM; ATF1; NRF1; JUNB; PRDM4; TAF4; BCL10; BRF2; NR2C1; REXO4; CHD9; RBL2; NR0B2; NFIB; HCFC2; NUP62; MYC; TAF7; GMEB2; RUVBL1; RYBP; SMAD5; EED; CREB3; NONO; YWHAB; HR; RFC1; PPRC1; CUX2; NCOR2; BCOR; ZNF576; CRK; BIRC2; BRPF1; RNF141; ILF2; ZNF143; LEF1; NFX1; PAX5; CEBPZ; HDGF; FOXO4; PPARG; TRIP6; MED7; CHD1; TADA2A; UIMC1; PSIP1; TOB1; THAP1; ZNF84; CCNA2; SAP30; ABL1; ARID1A; SMARCA2; SIX2; POU3F2; XRCC6; ZFP36L2; ZMYND8; NCOA3; ZBED2; ETS2; IRF2; SPEN; NLK; CHD7; TAF9B; TAF11; VGLL4; INSM1; HSF2; DPF2; SCAND1; ZMYM2; ASCL1; CNOT6; MED6; TMF1; NFKBIA; LYL1; TSC22D1; ANKRD1; BCL3; ZNF410; NCOR1; ZKSCAN1; HLTF; ZNF274; PIAS2; CDK8; NAB1; ISL1; ORC2; AES; BASP1; SIX1; ZNF281; RUNX1; ZNF165; NEDD8; BHLHE40; TRIM28; USF2; CBFB; TXNIP; PHF20; STAT3; HTATIP2; YEATS4; PIAS3; RCOR1; MGA; UBE2L3; TBL1XR1; NCOA6; MED23; HDAC9; BRD3; BATF3; COPS5; ENO1; TSC22D3; ZNF532; ERG; PEX2; PBX3; CERS6; TP53; DDX17; MED24; TLE4; AFF1; ERBB2; TCFL5; SNAI2; CEBPB; TOX3; FOXO1; SSBP3; ZNF589; FLNA; SALL2; SATB1; KDM5D